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https://www.readbyqxmd.com/read/27749484/postoperative-nonsteroidal-anti-inflammatory-drug-use-and-intestinal-anastomotic-dehiscence-a-systematic-review-and-meta-analysis
#1
Stephen A Smith, Derek J Roberts, Mark E Lipson, W Donald Buie, Anthony R MacLean
BACKGROUND: Nonsteroidal anti-inflammatory drugs are commonly used analgesics in colorectal surgery. Controversy exists regarding the potential association between these drugs and anastomotic dehiscence. OBJECTIVE: This study aimed to determine whether postoperative nonsteroidal anti-inflammatory drug use is associated with intestinal anastomotic dehiscence. DATA SOURCES: PubMed, EMBASE, CENTRAL, and references of included articles were searched without date or language restriction...
November 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/25482469/effect-of-intraoperative-infiltration-with-local-anesthesia-on-the-development-of-chronic-pain-after-inguinal-hernia-repair-a-randomized-triple-blinded-placebo-controlled-trial
#2
RANDOMIZED CONTROLLED TRIAL
Anita Kurmann, Henning Fischer, Salome Dell-Kuster, Rachel Rosenthal, Laurent Audigé, Guido Schüpfer, Jürg Metzger, Philipp Honigmann
BACKGROUND: Chronic pain is a common complication after inguinal hernia repair. The objective of this randomized trial was to assess the effect of intraoperative infiltration with local anesthetic versus placebo on the development of chronic pain after inguinal hernia repair. METHODS: Patients with single- or double-sided inguinal hernia were enrolled in a randomized, controlled, triple-blinded trial with a sequential adaptive design. Hernias were randomized to 1 of 2 treatment groups...
January 2015: Surgery
https://www.readbyqxmd.com/read/21254041/randomized-clinical-trial-comparing-polypropylene-or-polydioxanone-for-midline-abdominal-wall-closure
#3
RANDOMIZED CONTROLLED TRIAL
A Bloemen, P van Dooren, B F Huizinga, A G M Hoofwijk
BACKGROUND: Incisional hernia is a frequent complication of abdominal surgery, often requiring surgical intervention. This prospective randomized trial compared suture materials for closure of the fascia after abdominal surgery. METHODS: In 456 patients the abdominal fascia was closed with either non-absorbable (polypropylene; Prolene(®)) or absorbable (polydioxanone; PDS(®)) suture material. Follow-up was by clinical examination and ultrasonography at 6-month intervals...
May 2011: British Journal of Surgery
https://www.readbyqxmd.com/read/21964681/randomized-clinical-trial-of-fibrin-sealant-versus-titanium-tacks-for-mesh-fixation-in-laparoscopic-umbilical-hernia-repair
#4
RANDOMIZED CONTROLLED TRIAL
J R Eriksen, T Bisgaard, S Assaadzadeh, L Nannestad Jorgensen, J Rosenberg
BACKGROUND: The use of tacks for mesh fixation may induce pain after surgery for ventral hernia. The aim of this study was to compare postoperative pain after laparoscopic ventral hernia repair (LVHR) with conventional mesh fixation using titanium tacks versus fibrin sealant (FS). METHODS: This randomized clinical trial included patients with an umbilical hernia defect ranging from 1·5 to 5 cm at three Danish hernia centres. Participants were assigned randomly to FS or titanium tack fixation...
November 2011: British Journal of Surgery
https://www.readbyqxmd.com/read/24663481/prevention-of-incisional-hernia-in-midline-laparotomy-with-an-onlay-mesh-a-randomized-clinical-trial
#5
RANDOMIZED CONTROLLED TRIAL
A Caro-Tarrago, C Olona Casas, A Jimenez Salido, E Duque Guilera, F Moreno Fernandez, V Vicente Guillen
OBJECTIVE: Our objective was to evaluate the prevention of incisional hernia (IH) during the postoperative period of a midline laparotomy during elective surgery. MATERIAL AND METHODS: A controlled, prospective, randomized, and blind study was carried out. The patients in group A (mesh) were fitted with a polypropylene mesh, to reinforce the standard abdominal wall closure. The patients in group B (non-mesh) underwent a standard abdominal wall closure and were not fitted with the mesh...
September 2014: World Journal of Surgery
https://www.readbyqxmd.com/read/25384994/use-of-a-pathway-quality-improvement-care-bundle-to-reduce-mortality-after-emergency-laparotomy
#6
MULTICENTER STUDY
S Huddart, C J Peden, M Swart, B McCormick, M Dickinson, M A Mohammed, N Quiney
BACKGROUND: Emergency laparotomies in the U.K., U.S.A. and Denmark are known to have a high risk of death, with accompanying evidence of suboptimal care. The emergency laparotomy pathway quality improvement care (ELPQuiC) bundle is an evidence-based care bundle for patients undergoing emergency laparotomy, consisting of: initial assessment with early warning scores, early antibiotics, interval between decision and operation less than 6 h, goal-directed fluid therapy and postoperative intensive care...
January 2015: British Journal of Surgery
https://www.readbyqxmd.com/read/23903454/impact-of-wound-edge-protection-devices-on-surgical-site-infection-after-laparotomy-multicentre-randomised-controlled-trial-rossini-trial
#7
RANDOMIZED CONTROLLED TRIAL
Thomas D Pinkney, Melanie Calvert, David C Bartlett, Adrian Gheorghe, Val Redman, George Dowswell, William Hawkins, Tony Mak, Haney Youssef, Caroline Richardson, Steven Hornby, Laura Magill, Richard Haslop, Sue Wilson, Dion Morton
OBJECTIVE: To determine the clinical effectiveness of wound edge protection devices in reducing surgical site infection after abdominal surgery. DESIGN: Multicentre observer blinded randomised controlled trial. PARTICIPANTS: Patients undergoing laparotomy at 21 UK hospitals. INTERVENTIONS: Standard care or the use of a wound edge protection device during surgery. MAIN OUTCOME MEASURES: Surgical site infection within 30 days of surgery, assessed by blinded clinicians at seven and 30 days and by patient's self report for the intervening period...
July 31, 2013: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/16252314/systematic-review-and-meta-analysis-of-the-effectiveness-of-antibiotic-prophylaxis-in-prevention-of-wound-infection-after-mesh-repair-of-abdominal-wall-hernia
#8
REVIEW
T J Aufenacker, M J W Koelemay, D J Gouma, M P Simons
BACKGROUND: The aim was to determine whether systemic antibiotic prophylaxis prevented wound infection after repair of abdominal wall hernia with mesh. METHODS: This was a systematic review of the available literature identified from multiple databases using the terms 'hernia' and 'antibiotic prophylaxis'. Randomized placebo-controlled trials of antibiotic prophylaxis in abdominal wall mesh hernia repair with explicitly defined wound infection criteria and a minimum follow-up of 1 month were included...
January 2006: British Journal of Surgery
https://www.readbyqxmd.com/read/16930145/the-role-of-antibiotic-prophylaxis-in-elective-tension-free-mesh-inguinal-hernia-repair-results-of-a-single-centre-prospective-randomised-trial
#9
RANDOMIZED CONTROLLED TRIAL
G Tzovaras, S Delikoukos, G Christodoulides, M Spyridakis, F Mantzos, K Tepetes, E Athanassiou, C Hatzitheofilou
Hernia repair is one of the so-called clean operations. Many surgeons, however, use antibiotics, especially in the mesh repair era, without strong evidence to support this policy. We conducted a single-centre prospective randomised trial with a view to clarify this issue on a scientific basis. From January 2000 all patients undergoing elective inguinal hernia repair using a tension-free polypropylene mesh technique, provided they fulfilled predetermined criteria, were randomised to have a single dose of amoxicillin and clavoulanic acid or placebo in a double-blind manner...
February 2007: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/17178958/povidone-iodine-vs-sodium-hypochlorite-enema-for-mechanical-preparation-before-elective-open-colonic-or-rectal-resection-with-primary-anastomosis-a-multicenter-randomized-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Alain Valverde, Simon Msika, Reza Kianmanesh, Jean-Marie Hay, Anne-Cécile Couchard, Yves Flamant, Abe Fingerhut, Pierre-Louis Fagniez
HYPOTHESIS: The anti-infective actions of povidone-iodine (PVI) and sodium hypochlorite enemas are different. DESIGN: Prospective, randomized, single-blind study. SETTING: Multicenter. PATIENTS: Five hundred seventeen consecutive patients with colorectal carcinoma or sigmoid diverticular disease undergoing elective open colorectal resection, followed by primary anastomosis. INTERVENTION: All patients received senna (1-2 packages diluted in a glass of water) at 6 pm the evening before surgery...
December 2006: Archives of Surgery
https://www.readbyqxmd.com/read/22644622/preservation-versus-division-of-ilioinguinal-nerve-on-open-mesh-repair-of-inguinal-hernia-a-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
Wayne Hsu, Ching-Shyang Chen, Hung-Chia Lee, Hung-Hua Liang, Li-Jen Kuo, Po-Li Wei, Ka-Wai Tam
BACKGROUND: Chronic groin pain after inguinal hernia repair, a serious problem, is caused by entrapment of the ilioinguinal nerve either by mesh or development of fibrosis. Division of the ilioinguinal nerve during hernioplasty has been found to reduce the incidence of chronic groin pain. However, the traditional approach favors preservation of the ilioinguinal nerve during open hernia repair. METHODS: We conducted a systematic review and meta-analysis of randomized controlled trials that compared the outcomes of preservation versus division of the ilioinguinal nerve during open mesh repair of inguinal hernia...
October 2012: World Journal of Surgery
https://www.readbyqxmd.com/read/25789827/randomized-multicentre-feasibility-trial-of-intermediate-care-versus-standard-ward-care-after-emergency-abdominal-surgery-incare-trial
#12
RANDOMIZED CONTROLLED TRIAL
M Vester-Andersen, T Waldau, J Wetterslev, M H Møller, J Rosenberg, L N Jørgensen, J C Jakobsen, A M Møller
BACKGROUND: Emergency abdominal surgery carries a considerable risk of death and postoperative complications. Early detection and timely management of complications may reduce mortality. The aim was to evaluate the effect and feasibility of intermediate care compared with standard ward care in patients who had emergency abdominal surgery. METHODS: This was a randomized clinical trial carried out in seven Danish hospitals. Eligible for inclusion were patients with an Acute Physiology And Chronic Health Evaluation (APACHE) II score of at least 10 who were ready to be transferred to the surgical ward within 24 h of emergency abdominal surgery...
May 2015: British Journal of Surgery
https://www.readbyqxmd.com/read/15249409/randomized-controlled-trial-of-preservation-or-elective-division-of-ilioinguinal-nerve-on-open-inguinal-hernia-repair-with-polypropylene-mesh
#13
RANDOMIZED CONTROLLED TRIAL
Marcello Picchio, Domenico Palimento, Ugo Attanasio, Pietro Filippo Matarazzo, Chiara Bambini, Angelo Caliendo
HYPOTHESIS: Our study aimed to evaluate the effect of preservation or elective division of the ilioinguinal nerve on pain and postoperative symptoms after open inguinal hernia repair with mesh. DESIGN: Double-blind, randomized trial. SETTING: Four public, government-financed hospitals in Italy. PATIENTS: From January 1, 1997, to June 30, 2002, 813 patients with primary inguinal hernia were randomly allocated to undergo inguinal hernia repair either with ilioinguinal nerve preservation (408 patients, group A) or elective transection (405 patients, group B)...
July 2004: Archives of Surgery
https://www.readbyqxmd.com/read/25776855/meta-analysis-of-the-predictive-value-of-c-reactive-protein-for-infectious-complications-in-abdominal-surgery
#14
REVIEW
M Adamina, T Steffen, I Tarantino, U Beutner, B M Schmied, R Warschkow
BACKGROUND: The aim of this analysis was to assess the predictive value of C-reactive protein (CRP) for the early detection of postoperative infectious complications after a variety of abdominal operations. METHODS: A meta-analysis of seven cohort studies from a single institution was performed. Laparoscopic gastric bypass and colectomies, as well as open resections of cancer of the colon, rectum, pancreas, stomach and oesophagus, were included. The predictive value of CRP was assessed by the area under the curve (AUC) of the receiver operating characteristic (ROC) curve...
May 2015: British Journal of Surgery
https://www.readbyqxmd.com/read/26023037/value-of-peritoneal-drain-placement-after-total-gastrectomy-for-gastric-adenocarcinoma-a-multi-institutional-analysis-from-the-us-gastric-cancer-collaborative
#15
MULTICENTER STUDY
Gregory C Dann, Malcolm H Squires, Lauren M Postlewait, David A Kooby, George A Poultsides, Sharon M Weber, Mark Bloomston, Ryan C Fields, Timothy M Pawlik, Konstantinos I Votanopoulos, Carl R Schmidt, Aslam Ejaz, Alexandra W Acher, David J Worhunsky, Neil Saunders, Douglas S Swords, Linda X Jin, Clifford S Cho, Emily R Winslow, Maria C Russell, Charles A Staley, Shishir K Maithel, Kenneth Cardona
BACKGROUND: The effect of routine drainage after abdominal surgery with enteric anastomoses is controversial. In particular, the role of peritoneal drain (PD) placement after total gastrectomy for adenocarcinoma is not well established. METHODS: Patients who underwent total gastrectomy for gastric adenocarcinoma (GAC) at seven institutions from the US Gastric Cancer Collaborative, from 2000 to 2012, were identified. The association of PD placement with postoperative outcomes was analyzed...
December 2015: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/25663512/abdominal-drainage-to-prevent-intra-peritoneal-abscess-after-open-appendectomy-for-complicated-appendicitis
#16
Yao Cheng, Shiyi Zhou, Rongxing Zhou, Jiong Lu, Sijia Wu, Xianze Xiong, Hui Ye, Yixin Lin, Taixiang Wu, Nansheng Cheng
BACKGROUND: Appendectomy, the surgical removal of the appendix, is performed primarily for acute appendicitis. Patients who undergo appendectomy for complicated appendicitis, defined as gangrenous or perforated appendicitis, are more likely to suffer from postoperative complications. The routine use of abdominal drainage to reduce postoperative complications after appendectomy for complicated appendicitis is controversial. OBJECTIVES: To assess the safety and efficacy of abdominal drainage to prevent intra-peritoneal abscess after open appendectomy for complicated appendicitis...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/21833971/abdominal-drainage-versus-no-drainage-post-gastrectomy-for-gastric-cancer
#17
REVIEW
Zhen Wang, Junqiang Chen, Ka Su, Zhiyong Dong
BACKGROUND: Gastrectomy remains the primary therapeutic method for resectable gastric cancer. Thought of as an important measure to reduce post-operative complications and mortality, abdominal drainage was used widely after gastrectomy for gastric cancer in previous decades. The benefits of abdominal drainage have been questioned by researchers in recent years. OBJECTIVES: The objectives of this review were to access the benefits and harms of routine abdominal drainage post gastrectomy for gastric cancer...
2011: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/24646528/the-nota-study-non-operative-treatment-for-acute-appendicitis-prospective-study-on-the-efficacy-and-safety-of-antibiotics-amoxicillin-and-clavulanic-acid-for-treating-patients-with-right-lower-quadrant-abdominal-pain-and-long-term-follow-up-of-conservatively
#18
RANDOMIZED CONTROLLED TRIAL
Salomone Di Saverio, Andrea Sibilio, Eleonora Giorgini, Andrea Biscardi, Silvia Villani, Federico Coccolini, Nazareno Smerieri, Michele Pisano, Luca Ansaloni, Massimo Sartelli, Fausto Catena, Gregorio Tugnoli
OBJECTIVES: To assess the safety and efficacy of antibiotics treatment for suspected acute uncomplicated appendicitis and to monitor the long term follow-up of non-operated patients. BACKGROUND: Right lower quadrant abdominal pain is a common cause of emergency department admission. The natural history of acute appendicitis nonoperatively treated with antibiotics remains unclear. METHODS: In 2010, a total of 159 patients [mean AIR (Appendicitis Inflammatory Response) score = 4...
July 2014: Annals of Surgery
https://www.readbyqxmd.com/read/16822992/perioperative-chemotherapy-versus-surgery-alone-for-resectable-gastroesophageal-cancer
#19
RANDOMIZED CONTROLLED TRIAL
David Cunningham, William H Allum, Sally P Stenning, Jeremy N Thompson, Cornelis J H Van de Velde, Marianne Nicolson, J Howard Scarffe, Fiona J Lofts, Stephen J Falk, Timothy J Iveson, David B Smith, Ruth E Langley, Monica Verma, Simon Weeden, Yu Jo Chua, MAGIC Trial Participants
BACKGROUND: A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable locally advanced or metastatic gastric adenocarcinoma. We assessed whether the addition of a perioperative regimen of ECF to surgery improves outcomes among patients with potentially curable gastric cancer. METHODS: We randomly assigned patients with resectable adenocarcinoma of the stomach, esophagogastric junction, or lower esophagus to either perioperative chemotherapy and surgery (250 patients) or surgery alone (253 patients)...
July 6, 2006: New England Journal of Medicine
https://www.readbyqxmd.com/read/24770891/mesh-fixation-at-laparoscopic-inguinal-hernia-repair-a-meta-analysis-comparing-tissue-glue-and-tack-fixation
#20
REVIEW
Nehal S Shah, Catherine Fullwood, Ajith K Siriwardena, Aali J Sheen
BACKGROUND: The aim of this study was to conduct a comprehensive systematic review comparing tissue glue (TG) against tacks/staples for mesh fixation in laparoscopic (totally extra-peritoneal and trans-abdominal pre-peritoneal) groin hernia repair with the incidence of post-operative chronic pain as the primary outcome measure. METHODS: A computerized search of MEDLINE, EMBASE, and Cochrane databases for the period from 1 January 1,990 to 30 June 2013 produced 39 reports...
October 2014: World Journal of Surgery
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