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Propofol for EA

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Sophia L van Hoff, Elizabeth S O'Neill, Lianna C Cohen, Brian A Collins
INTRODUCTION: Emergence agitation (EA) is common after sevoflurane anesthesia in children, and can lead to distressing inconsolability, agitation, crying, and injury. Use of a single dose of the short-acting sedative-hypnotic agent propofol at the end of a procedure has shown promise for preventing EA, but evidence evaluating the efficacy and safety of this approach has not been formally summarized. OBJECTIVE: The objective of this review was to assess the effects of a prophylactic dose of propofol vs placebo on the incidence and severity of EA in children age 0-13 years receiving general inhalational anesthesia...
July 2015: Paediatric Anaesthesia
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