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Anti-platelete in HD

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4 papers 0 to 25 followers
https://www.readbyqxmd.com/read/30042225/drug-coated-balloon-angioplasty-in-failing-av-fistulas-a-randomized-controlled-trial
#1
Scott O Trerotola, Jeffrey Lawson, Prabir Roy-Chaudhury, Theodore F Saad
BACKGROUND: Restenosis remains a problem in hemodialysis access interventions. Paclitaxel-coated balloons have shown promise in reducing access-related restenosis in small trials. The primary hypotheses for our multicenter trial were superior effectiveness at 180 days and noninferior safety at 30 days of a drug-coated balloon compared with conventional angioplasty for treatment of dysfunctional arteriovenous fistulas. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This randomized trial enrolled 285 patients with dysfunctional arteriovenous fistulas at 23 centers...
August 7, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/30010473/diabetes-decreases-patency-of-tunneled-catheters-in-hemodialysis-patients-after-first-effective-thrombolysis-with-urokinase
#2
Dominika Wójtowicz, Dominika Cholewa, Anna M Faba, Beata Domańska, Joanna Kokoszka, Konrad Kopacz, Rafał Ficek, Tomasz Irzyniec, Sylwia E Rotkegel, Jerzy Chudek
INTRODUCTION: Fibrinolysis is one of the methods extending the use of vascular access in patients with tunneled venous catheters thrombosis. The aim of this study was to assess one-year maintenance of tunneled catheters patency after first effective thrombolysis with urokinase and identify its predictors. METHODS: Retrospective analysis included 85 patients (age 69 ± 13 years) with permanent venous catheter thrombosis treated with urokinase at one center in the period 2010-2016...
November 2018: Renal Failure
https://www.readbyqxmd.com/read/25913603/anticoagulation-in-chronic-hemodialysis-progress-toward-an-optimal-approach
#3
REVIEW
Michèle Kessler, Frédérique Moureau, Philippe Nguyen
Appropriate anticoagulation for hemodialysis (HD) requires a subtle balance between under- and over-heparinization to prevent extracorporeal circuit (ECC) clotting and bleeding, respectively. We discuss five key issues relating to anticoagulation therapy for chronic HD in adults following a review of relevant literature published since 2002: (i) options for standardization of anticoagulation in HD settings. The major nephrology societies have issued low evidence level recommendations on this subject. Interventional studies have generally investigated novel low-molecular weight heparins and provided data on safety of dosing regimens that cannot readily be extrapolated to clinical practice; (ii) identification of clinical and biological parameters to aid individualization of anticoagulation treatment...
September 2015: Seminars in Dialysis
https://www.readbyqxmd.com/read/22431677/effects-of-antiplatelet-therapy-on-mortality-and-cardiovascular-and-bleeding-outcomes-in-persons-with-chronic-kidney-disease-a-systematic-review-and-meta-analysis
#4
REVIEW
Suetonia C Palmer, Lucia Di Micco, Mona Razavian, Jonathan C Craig, Vlado Perkovic, Fabio Pellegrini, Massimiliano Copetti, Giusi Graziano, Gianni Tognoni, Meg Jardine, Angela Webster, Antonio Nicolucci, Sophia Zoungas, Giovanni F M Strippoli
BACKGROUND: Antiplatelet agents are used to prevent cardiovascular events; however, treatment effects may differ in persons with chronic kidney disease (CKD) because atherosclerotic disease is less prevalent, whereas bleeding hazards may be increased in this population. PURPOSE: To summarize the effects of antiplatelet treatment on cardiovascular events, mortality, and bleeding in persons with CKD. DATA SOURCES: Embase and Cochrane databases through November 2011 without language restriction...
March 20, 2012: Annals of Internal Medicine
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