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Distal pancreatectomty

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3 papers 0 to 25 followers
Linda W Ma, Ismael Dominguez-Rosado, Renee L Gennarelli, Peter B Bach, Mithat Gonen, Michael I D'Angelica, Ronald P DeMatteo, T Peter Kingham, Murray F Brennan, William R Jarnagin, Peter J Allen
OBJECTIVE: The objective of this study was to determine the costs of clinically significant postoperative pancreatic fistula (POPF) and to evaluate the cost-effectiveness of routine pasireotide use. SUMMARY OF BACKGROUND DATA: We recently completed a prospective randomized trial that demonstrated an 11.7% absolute risk reduction of clinically significant POPF with use of perioperative pasireotide in patients undergoing pancreaticoduodenectomy or distal pancreatectomy [POPF: pasireotide (n = 152), 9% vs placebo (n = 148), 21%; P = 0...
July 15, 2016: Annals of Surgery
Manabu Kawai, Seiko Hirono, Ken-Ichi Okada, Masayuki Sho, Yoshiyuki Nakajima, Hidetoshi Eguchi, Hiroaki Nagano, Hisashi Ikoma, Ryou Morimura, Yutaka Takeda, Shin Nakahira, Kazuhiro Suzumura, Jiro Fujimoto, Hiroki Yamaue
OBJECTIVES: The aim of this study was to evaluate in a multicenter randomized controlled trial (RCT) whether pancreaticojejunostomy (PJ) of pancreatic stump decreases the incidence of pancreatic fistula after distal pancreatectomy (DP) compared with stapler closure. BACKGROUND: Several studies reported that PJ of pancreatic stump reduces the incidence of pancreatic fistula after DP. However, no RCT has confirmed the efficacy of PJ of pancreatic stump. METHODS: One hundred thirty-six patients scheduled for DP were enrolled in this study between June 2011 and March 2014 at 6 high-volume surgical centers in Japan...
July 2016: Annals of Surgery
Eugene P Ceppa, Robert M McCurdy, David C Becerra, E Molly Kilbane, Nicholas J Zyromski, Attila Nakeeb, C Max Schmidt, Keith D Lillemoe, Henry A Pitt, Michael G House
BACKGROUND: Pancreatic fistula remains the primary source of morbidity following distal pancreatectomy. Previous studies have reported specific methods of parenchymal transection/stump sealing in an effort to decrease the pancreatic fistula rate with highly variable results. The aim of this study was to determine postoperative outcomes following various pancreatic stump-sealing methods. STUDY DESIGN: All cases of distal pancreatectomy were reviewed at a single institution between January 2008 and June 2011 and were monitored with complete 30-day outcomes through ACS-NSQIP...
August 2015: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
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