Frédéric D Broccard, Tim Mullen, Yu Mike Chi, David Peterson, John R Iversen, Mike Arnold, Kenneth Kreutz-Delgado, Tzyy-Ping Jung, Scott Makeig, Howard Poizner, Terrence Sejnowski, Gert Cauwenberghs
Traditional approaches for neurological rehabilitation of patients affected with movement disorders, such as Parkinson's disease (PD), dystonia, and essential tremor (ET) consist mainly of oral medication, physical therapy, and botulinum toxin injections. Recently, the more invasive method of deep brain stimulation (DBS) showed significant improvement of the physical symptoms associated with these disorders. In the past several years, the adoption of feedback control theory helped DBS protocols to take into account the progressive and dynamic nature of these neurological movement disorders that had largely been ignored so far...
August 2014: Annals of Biomedical Engineering