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General Paediatric Collection

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12 papers 0 to 25 followers
By Ayat Al-Safar Senior Registerer General Paediatrics
https://www.readbyqxmd.com/read/23449856/low-fat-yoghurt-intake-in-pregnancy-associated-with-increased-child-asthma-and-allergic-rhinitis-risk-a-prospective-cohort-study
#1
Ekaterina Maslova, Thorhallur I Halldorsson, Marin Strøm, Sjurdur F Olsen
Dairy products are important sources of micronutrients, fatty acids and probiotics which could modify the risk of child asthma and allergy development. To examine the association of dairy product intake during pregnancy with child asthma and allergic rhinitis at 18 months and 7 years in the Danish National Birth Cohort, data on milk and yoghurt consumption were collected in mid-pregnancy (25th week of gestation) using a validated FFQ (n 61 909). At 18 months, we evaluated asthma and wheeze using interview data...
July 6, 2012: Journal of Nutritional Science
https://www.readbyqxmd.com/read/23592105/association-between-childhood-migraine-and-history-of-infantile-colic
#2
MULTICENTER STUDY
Silvia Romanello, Daniele Spiri, Elena Marcuzzi, Anna Zanin, Priscilla Boizeau, Simon Riviere, Audrey Vizeneux, Raffaella Moretti, Ricardo Carbajal, Jean-Christophe Mercier, Chantal Wood, Gian Vincenzo Zuccotti, Giovanni Crichiutti, Corinne Alberti, Luigi Titomanlio
IMPORTANCE: Infantile colic is a common cause of inconsolable crying during the first months of life and has been thought to be a pain syndrome. Migraine is a common cause of headache pain in childhood. Whether there is an association between these 2 types of pain in unknown. OBJECTIVE: To investigate a possible association between infantile colic and migraines in childhood. DESIGN, SETTING, AND PARTICIPANTS: A case-control study of 208 consecutive children aged 6 to 18 years presenting to the emergency department and diagnosed as having migraines in 3 European tertiary care hospitals between April 2012 and June 2012...
April 17, 2013: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/16917115/sildenafil-prevents-rebound-pulmonary-hypertension-after-withdrawal-of-nitric-oxide-in-children
#3
RANDOMIZED CONTROLLED TRIAL
Poongundran Namachivayam, Ulf Theilen, Warwick W Butt, Sian M Cooper, Daniel J Penny, Lara S Shekerdemian
RATIONALE: Rebound pulmonary hypertension (PHT) can complicate the weaning of nitric oxide (NO), and is in part related to transient depletion of intrinsic cyclic guanosine monophosphate. Rebound is characterized by increased pulmonary arterial (PA) pressure, cardiopulmonary instability, and in some cases, the need to continue NO beyond the intended period of use. There is anecdotal evidence that sildenafil, a phosphodiesterase-5 inhibitor, may prevent recurrence of rebound. OBJECTIVES: We investigated the role of sildenafil in preventing rebound (an increase in PA pressure of 20% or greater, or failure to discontinue NO) in patients in whom previous attempts had not been made to wean from NO...
November 1, 2006: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/23642047/oxygen-saturation-and-outcomes-in-preterm-infants
#4
RANDOMIZED CONTROLLED TRIAL
Ben J Stenson, William O Tarnow-Mordi, Brian A Darlow, John Simes, Edmund Juszczak, Lisa Askie, Malcolm Battin, Ursula Bowler, Roland Broadbent, Pamela Cairns, Peter Graham Davis, Sanjeev Deshpande, Mark Donoghoe, Lex Doyle, Brian W Fleck, Alpana Ghadge, Wendy Hague, Henry L Halliday, Michael Hewson, Andrew King, Adrienne Kirby, Neil Marlow, Michael Meyer, Colin Morley, Karen Simmer, Win Tin, Stephen P Wardle, Peter Brocklehurst
BACKGROUND: The clinically appropriate range for oxygen saturation in preterm infants is unknown. Previous studies have shown that infants had reduced rates of retinopathy of prematurity when lower targets of oxygen saturation were used. METHODS: In three international randomized, controlled trials, we evaluated the effects of targeting an oxygen saturation of 85 to 89%, as compared with a range of 91 to 95%, on disability-free survival at 2 years in infants born before 28 weeks' gestation...
May 30, 2013: New England Journal of Medicine
https://www.readbyqxmd.com/read/25941311/early-psychosocial-exposures-hair-cortisol-levels-and-disease-risk
#5
Jerker Karlén, Johnny Ludvigsson, Max Hedmark, Åshild Faresjö, Elvar Theodorsson, Tomas Faresjö
BACKGROUND: Early psychosocial exposures are increasingly recognized as being crucial to health throughout life. A possible mechanism could be physiologic dysregulation due to stress. Cortisol in hair is a new biomarker assessing long-term hypothalamic-pituitary-adrenal axis activity. The objective was to investigate whether early-life adverse psychosocial circumstances influence infant cortisol levels in hair and health outcomes in children prospectively until age 10. METHODS: A cohort study in the general community using a questionnaire covering 11 psychosocial items in the family during pregnancy and the cumulative incidence of diagnoses until age 10 years in 1876 children...
June 2015: Pediatrics
https://www.readbyqxmd.com/read/17101711/vitamin-k-prophylaxis-for-preterm-infants-a-randomized-controlled-trial-of-3-regimens
#6
RANDOMIZED CONTROLLED TRIAL
Paul Clarke, Simon J Mitchell, Robert Wynn, Shanmuga Sundaram, Valerie Speed, Elizabeth Gardener, Donna Roeves, Martin J Shearer
OBJECTIVE: Preterm infants may be at particular risk from either inadequate or excessive vitamin K prophylaxis. Our goal was to assess vitamin K status and metabolism in preterm infants after 3 regimens of prophylaxis. METHODS: Infants <32 weeks' gestation were randomized to receive 0.5 mg (control) or 0.2 mg of vitamin K1 intramuscularly or 0.2 mg intravenously after delivery. Primary outcome measures were serum vitamin K1, its epoxide metabolite (vitamin K1 2,3-epoxide), and undercarboxylated prothrombin assessed at birth, 5 days, and after 2 weeks of full enteral feeds...
December 2006: Pediatrics
https://www.readbyqxmd.com/read/25919999/imprinting-latchment-and-displacement-a-mini-review-of-early-instinctual-behaviour-in-newborn-infants-influencing-breastfeeding-success
#7
REVIEW
Elsie J Mobbs, George A Mobbs, Anthony E D Mobbs
UNLABELLED: Instinctive behaviours have evolved favouring the mother-infant dyad based on fundamental processes of neurological development, including oral tactile imprinting and latchment. Latchment is the first stage of emotional development based on the successful achievement of biological imprinting. The mechanisms underpinning imprinting are identified and the evolutionary benefits discussed. CONCLUSION: It is proposed that the oral tactile imprint to the breast is a keystone for optimal latchment and breastfeeding, promoting evolutionary success...
January 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/21746729/room-air-versus-oxygen-administration-for-resuscitation-of-preterm-infants-the-roar-study
#8
RANDOMIZED CONTROLLED TRIAL
Yacov Rabi, Nalini Singhal, Alberto Nettel-Aguirre
OBJECTIVE: We conducted a blinded, prospective, randomized control trial to determine which oxygen-titration strategy was most effective at achieving and maintaining oxygen saturations of 85% to 92% during delivery-room resuscitation. METHODS: Infants born at 32 weeks' gestation or less were resuscitated either with a static concentration of 100% oxygen (high-oxygen group) or using an oxygen-titration strategy starting from a concentration of 100% (moderate-oxygen group), or 21% oxygen (low-oxygen group)...
August 2011: Pediatrics
https://www.readbyqxmd.com/read/25896845/neonatal-intensive-care-unit-antibiotic-use
#9
Joseph Schulman, Robert J Dimand, Henry C Lee, Grace V Duenas, Mihoko V Bennett, Jeffrey B Gould
BACKGROUND AND OBJECTIVES: Treatment of suspected infection is a mainstay of the daily work in the NICU. We hypothesized that NICU antibiotic prescribing practice variation correlates with rates of proven infection, necrotizing enterocolitis (NEC), mortality, inborn admission, and with NICU surgical volume and average length of stay. METHODS: In a retrospective cohort study of 52,061 infants in 127 NICUs across California during 2013, we compared sample means and explored linear and nonparametric correlations, stratified by NICU level of care and lowest/highest antibiotic use rate quartiles...
May 2015: Pediatrics
https://www.readbyqxmd.com/read/25838786/time-needed-to-achieve-changes-in-oxygen-concentration-at-the-t-piece-resuscitator-during-respiratory-support-in-preterm-infants-in-the-delivery-room
#10
Graeme Follett, Po-Yin Cheung, Gerhard Pichler, Khalid Aziz, Georg M Schmölzer
OBJECTIVE: To measure the time needed to achieve changes in fraction of inspired oxygen concentration (FiO2) from the oxygen blender to the facemask during simulated neonatal resuscitation. METHOD: Two oxygen analyzers were placed at each end of the T-Piece. During simulated ventilation, the duration to achieve the set oxygen concentration at the facemask was measured. This was repeated at different gas flow rates (5 L/min, 8 L/min or 10 L/min) and different FiO2 changes (0...
March 2015: Paediatrics & Child Health
https://www.readbyqxmd.com/read/25900322/prenatal-acquired-cytomegalovirus-infection-should-be-considered-in-children-with-autism
#11
Mona-Lisa Engman, Mikael Sundin, Carmela Miniscalco, Joakim Westerlund, Ilona Lewensohn-Fuchs, Christopher Gillberg, Elisabeth Fernell
AIM: The aim of the study was to evaluate the prevalence of congenital cytomegalovirus infection (CMV) in a representative sample of children with autism spectrum disorder. METHODS: In a representative group of 115 preschool children with autism spectrum disorder, of whom 33 also had intellectual disability, the dried blood spots from the newborn metabolic screening were analysed for CMV DNA using TaqMan polymerase chain reaction. RESULTS: One of the 33 children with autism spectrum disorder and intellectual disability - 3% of that group - had congenital CMV infection...
August 2015: Acta Paediatrica
https://www.readbyqxmd.com/read/25907848/teaching-reading-to-children-with-neurofibromatosis-type-1-a-clinical-trial-with-random-assignment-to-different-approaches
#12
RANDOMIZED CONTROLLED TRIAL
Laura A Barquero, Angela M Sefcik, Laurie E Cutting, Sheryl L Rimrodt
AIM: Neurofibromatosis type 1 (NF1) is a genetic disorder with a cognitive profile that includes visual-spatial perception deficits and a high incidence of reading disability. There is a paucity of information about how this cognitively complex population responds to mainstream reading interventions. The clinical trial goals were to determine whether children and adolescents with NF1 and reading deficits (NF+RD) benefit from mainstream remedial reading programs and whether responsiveness varies with differences in program-related visual-spatial demands...
December 2015: Developmental Medicine and Child Neurology
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