Sunil H Patel, Robert G Uzzo, Alessandro Larcher, Benoit Peyronnet, Brian R Lane, Deepak Pruthi, Madhumitha Reddy, Umberto Capitanio, Shreyas Joshi, Sabrina Noyes, Ahmed Eldefrawy, Fady Ghali, Margaret F Meagher, Zachary A Hamilton, Kendrick Yim, Ryan Nasseri, Aaron W Bradshaw, Sumi Dey, Samer Kirmiz, Fang Wan, Michael A Liss, Karim Bensalah, Francesco Montorsi, Ithaar H Derweesh
BACKGROUND: The efficacy of partial nephrectomy (PN) in setting of pT3a pathologic-upstaged renal cell carcinoma (RCC) is controversial. We compared oncologic and functional outcomes of radical nephrectomy (RN) and PN in patients with upstaged pT3a RCC. PATIENTS AND METHODS: This was a multicenter retrospective analysis of patients with cT1-2N0M0 RCC upstaged to pT3a postoperatively. The primary outcome was recurrence-free survival, with secondary outcomes of overall survival and de novo estimated glomular filtration rate (eGFR) < 60...
December 2020: Clinical Genitourinary Cancer