collection
https://read.qxmd.com/read/21543672/comparison-of-nerve-transfers-and-nerve-grafting-for-traumatic-upper-plexus-palsy-a-systematic-review-and-analysis
#21
REVIEW
Rohit Garg, Gregory A Merrell, Howard J Hillstrom, Scott W Wolfe
BACKGROUND: In treating patients with brachial plexus injury, there are no comparative data on the outcomes of nerve grafts or nerve transfers for isolated upper trunk or C5-C6-C7 root injuries. The purpose of our study was to compare, with systematic review, the outcomes for modern intraplexal nerve transfers for shoulder and elbow function with autogenous nerve grafting for upper brachial plexus traumatic injuries. METHODS: PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were searched for studies in which patients had surgery for traumatic upper brachial plexus palsy within one year of injury and with a minimum follow-up of twelve months...
May 4, 2011: Journal of Bone and Joint Surgery. American Volume
https://read.qxmd.com/read/25690271/controversies-in-bariatric-surgery
#22
REVIEW
P E O'Brien
BACKGROUND: There are many controversies related to bariatric surgery. This review explores selected areas. METHODS: A combination of randomized clinical trials (RCTs), systematic reviews and expert opinion have been brought together to highlight areas of importance or conflict. RESULTS AND CONCLUSION: Metabolic surgery is an increasingly preferred term rather than bariatric or obesity surgery. Reporting should be standardized to include appropriate weight measures, valid disease measures and data on loss to follow-up...
May 2015: British Journal of Surgery
https://read.qxmd.com/read/25867111/screening-for-type-2-diabetes-mellitus-a-systematic-review-for-the-u-s-preventive-services-task-force
#23
REVIEW
Shelley Selph, Tracy Dana, Ian Blazina, Christina Bougatsos, Hetal Patel, Roger Chou
BACKGROUND: Screening for type 2 diabetes mellitus could lead to earlier identification and treatment of asymptomatic diabetes, impaired fasting glucose (IFG), or impaired glucose tolerance (IGT), potentially resulting in improved outcomes. PURPOSE: To update the 2008 U.S. Preventive Services Task Force review on diabetes screening in adults. DATA SOURCES: Cochrane databases and MEDLINE (2007 through October 2014) and relevant studies from previous Task Force reviews...
June 2, 2015: Annals of Internal Medicine
https://read.qxmd.com/read/24567149/top-10-mobile-apps-in-emergency-medicine
#24
REVIEW
Michelle Lin, Salim Rezaie, Iltifat Husain
Mobile apps are increasingly being used at the bedside as a part of clinical care. With almost 300 emergency medicine-related apps available in the Apple App Store, it can be overwhelming deciding which are most useful for emergency department providers. A Top 10 list of apps is highlighted which illustrate the many ways that quality apps can positively impact the care of emergency department patients.
May 2014: Emergency Medicine Journal: EMJ
https://read.qxmd.com/read/25856281/effect-of-facial-rejuvenation-surgery-on-perceived-attractiveness-femininity-and-personality
#25
JOURNAL ARTICLE
Michael J Reilly, Jaclyn A Tomsic, Stephen J Fernandez, Steven P Davison
IMPORTANCE: To date, the conversation about facial rejuvenation surgery has focused on one goal: youthfulness. However, human beings are judged throughout life based on many other characteristics and personal qualities conveyed by their faces. The term facial profiling has been used to describe this act of determining personality attributes through visual observation. OBJECTIVES: To introduce the concept of facial profiling to the surgical literature and to evaluate and quantify the changes in personality perception that occur with facial rejuvenation surgery...
May 2015: JAMA Facial Plastic Surgery
https://read.qxmd.com/read/25840767/nebulized-fentanyl-vs-intravenous-morphine-for-ed-patients-with-acute-abdominal-pain-a-randomized-double-blinded-placebo-controlled-clinical-trial
#26
RANDOMIZED CONTROLLED TRIAL
Travis Deaton, Jonathan D Auten, Michael A Darracq
Patients with acute abdominal pain commonly present to emergency departments. The safe and effective relief of discomfort is a concern to patients and physicians. Intravenous opioids are the traditional method used to provide pain relief in this setting, but intravenous access is time consuming and not always achievable. Alternative methods of pain control may therefore be necessary for the acute management of painful conditions without adding to the overall physical or psychological discomfort. The purpose of this study was to evaluate the feasibility of nebulized fentanyl (NF) in the alleviation of acute and undifferentiated abdominal pain...
June 2015: American Journal of Emergency Medicine
https://read.qxmd.com/read/25160843/time-based-physical-activity-interventions-for-weight-loss-a-randomized-trial
#27
RANDOMIZED CONTROLLED TRIAL
John M Jakicic, Amy D Rickman, Wei Lang, Kelliann K Davis, Bethany Barone Gibbs, Rebecca Neiberg, Marsha D Marcus
PURPOSE: This study aims to examine whether enhancing standard behavioral weight loss interventions (standard behavioral weight loss program (SBWP)) with additional strategies at the initiation of intervention (ADOPT) or providing the additional strategies at predetermined times over the intervention period (MAINTAIN) enhances 18-month weight loss. METHODS: This was a clinical trial of participants (N = 195; mean ± SEM: age, 43.2 ± 8.6 yr; body mass index, 33...
May 2015: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/25846899/progressive-fat-necrosis-after-breast-augmentation-with-autologous-lipotransfer-a-cause-of-long-lasting-high-fever-and-axillary-lymph-node-enlargement
#28
REVIEW
XiuQi Li, Xin Guo
UNLABELLED: Breast augmentation with autologous fat transfer has been widely practiced. However, this procedure is not exempt from complications even after technique refinement. This article aims to describe a case of long-lasting high fever, axillary node enlargement, and upper extremity dysfunction caused by liponecrosis after breast fat injection. Radiological and histological examination confirmed liponecrosis in bilateral breasts. Aspiration, drainage, and irrigation were performed along with empirical antibiotic treatment...
June 2015: Aesthetic Plastic Surgery
https://read.qxmd.com/read/25837246/effects-of-swimming-on-the-inflammatory-and-redox-response-in-a-model-of-allergic-asthma
#29
JOURNAL ARTICLE
T R Brüggemann, L C M Ávila, B Fortkamp, F R Greiffo, F Bobinski, L Mazzardo-Martins, D F Martins, M M M F Duarte, A Dafre, A R S Santos, M D Silva, L F Souza, R P Vieira, D C Hizume-Kunzler
In this study we hypothesized that swimming during sensitization phase could result in a preventive effect in mice with allergic asthma. Swiss mice were divided into 4 groups: Control and Swimming (non-sensitized), OVA and OVA+Swimming (sensitized). The allergic inflammation was induced by 2 intraperitoneal injections and 4 aerosol challenges using ovalbumin. Swimming sessions were performed at high intensity over 3 weeks. 48 h after the last challenge mice were euthanized. Swimming decreased OVA-increased total IgE, IL-1, IL-4, IL-5 and IL-6 levels, as well as the number of total cells, lymphocytes and eosinophils in bronchoalveolar lavage fluid, (p<0...
June 2015: International Journal of Sports Medicine
https://read.qxmd.com/read/25399275/association-of-inpatient-vs-outpatient-onset-of-st-elevation-myocardial-infarction-with-treatment-and-clinical-outcomes
#30
MULTICENTER STUDY
Prashant Kaul, Jerome J Federspiel, Xuming Dai, Sally C Stearns, Sidney C Smith, Michael Yeung, Hadi Beyhaghi, Lei Zhou, George A Stouffer
IMPORTANCE: Reperfusion times for ST-elevation myocardial infarction (STEMI) occurring in outpatients have improved significantly, but quality improvement efforts have largely ignored STEMI occurring in hospitalized patients (inpatient-onset STEMI). OBJECTIVE: To define the incidence and variables associated with treatment and outcomes of patients who develop STEMI during hospitalization for conditions other than acute coronary syndromes (ACS). DESIGN, SETTING, AND PARTICIPANTS: Retrospective observational analysis of STEMIs occurring between 2008 and 2011 as identified in the California State Inpatient Database...
November 19, 2014: JAMA
https://read.qxmd.com/read/25881930/chronic-performance-of-a-leadless-cardiac-pacemaker-1-year-follow-up-of-the-leadless-trial
#31
MULTICENTER STUDY
Reinoud E Knops, Fleur V Y Tjong, Petr Neuzil, Johannes Sperzel, Marc A Miller, Jan Petru, Jaroslav Simon, Lucie Sediva, Joris R de Groot, Srinivas R Dukkipati, Jacob S Koruth, Arthur A M Wilde, Josef Kautzner, Vivek Y Reddy
BACKGROUND: A leadless cardiac pacemaker (LCP) system was recently introduced to overcome lead-related complications of conventional pacing systems. To date, long-term results of an LCP system are unknown. OBJECTIVES: The aim of this study was to assess the complication incidence, electrical performance, and rate response characteristics within the first year of follow-up of patients implanted with an LCP. METHODS: We retrospectively assessed intermediate-term follow-up data for 31 of 33 patients from the LEADLESS trial cohort who had an indication for single-chamber pacing and received an LCP between December 2012 and April 2013...
April 21, 2015: Journal of the American College of Cardiology
https://read.qxmd.com/read/25892679/efficacy-and-safety-of-very-early-mobilisation-within-24-h-of-stroke-onset-avert-a-randomised-controlled-trial
#32
RANDOMIZED CONTROLLED TRIAL
(no author information available yet)
BACKGROUND: Early mobilisation after stroke is thought to contribute to the effects of stroke-unit care; however, the intervention is poorly defined and not underpinned by strong evidence. We aimed to compare the effectiveness of frequent, higher dose, very early mobilisation with usual care after stroke. METHODS: We did this parallel-group, single-blind, randomised controlled trial at 56 acute stroke units in five countries. Patients (aged ≥18 years) with ischaemic or haemorrhagic stroke, first or recurrent, who met physiological criteria were randomly assigned (1:1), via a web-based computer generated block randomisation procedure (block size of six), to receive usual stroke-unit care alone or very early mobilisation in addition to usual care...
July 4, 2015: Lancet
https://read.qxmd.com/read/25818710/current-and-emerging-rehabilitation-for-concussion-a-review-of-the-evidence
#33
REVIEW
Steven P Broglio, Michael W Collins, Richelle M Williams, Anne Mucha, Anthony P Kontos
Concussion is one of the most hotly debated topics in sports medicine today. Research surrounding concussion has experienced significant growth recently, especially in the areas of incidence, assessment, and recovery. However, there is limited research on the most effective rehabilitation approaches for this injury. This review evaluates the current literature for evidence for and against physical and cognitive rest and the emerging areas targeting vestibular, oculomotor, and pharmacologic interventions for the rehabilitation of sport-related concussion...
April 2015: Clinics in Sports Medicine
https://read.qxmd.com/read/25665067/functional-trajectories-among-older-persons-before-and-after-critical-illness
#34
JOURNAL ARTICLE
Lauren E Ferrante, Margaret A Pisani, Terrence E Murphy, Evelyne A Gahbauer, Linda S Leo-Summers, Thomas M Gill
IMPORTANCE: Little is known about functional trajectories of older persons in the year before and after admission to the intensive care unit (ICU) or how pre-ICU functional trajectories affect post-ICU functional trajectories and death. OBJECTIVES: To characterize functional trajectories in the year before and after ICU admission and to evaluate the associations among pre-ICU functional trajectories and post-ICU functional trajectories, short-term mortality, and long-term mortality...
April 2015: JAMA Internal Medicine
https://read.qxmd.com/read/23992601/saxagliptin-and-cardiovascular-outcomes-in-patients-with-type-2-diabetes-mellitus
#35
RANDOMIZED CONTROLLED TRIAL
Benjamin M Scirica, Deepak L Bhatt, Eugene Braunwald, P Gabriel Steg, Jaime Davidson, Boaz Hirshberg, Peter Ohman, Robert Frederich, Stephen D Wiviott, Elaine B Hoffman, Matthew A Cavender, Jacob A Udell, Nihar R Desai, Ofri Mosenzon, Darren K McGuire, Kausik K Ray, Lawrence A Leiter, Itamar Raz
BACKGROUND: The cardiovascular safety and efficacy of many current antihyperglycemic agents, including saxagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor, are unclear. METHODS: We randomly assigned 16,492 patients with type 2 diabetes who had a history of, or were at risk for, cardiovascular events to receive saxagliptin or placebo and followed them for a median of 2.1 years. Physicians were permitted to adjust other medications, including antihyperglycemic agents...
October 3, 2013: New England Journal of Medicine
https://read.qxmd.com/read/25877491/impact-of-voluntary-fortification-and-supplement-use-on-dietary-intakes-and-biomarker-status-of-folate-and-vitamin-b-12-in-irish-adults
#36
JOURNAL ARTICLE
Sinéad M Hopkins, Michael J Gibney, Anne P Nugent, Helene McNulty, Anne M Molloy, John M Scott, Albert Flynn, J J Strain, Mary Ward, Janette Walton, Breige A McNulty
BACKGROUND: Ireland has traditionally operated a liberal policy of voluntary fortification, but little is known about how this practice, along with supplement use, affects population intakes and status of folate and vitamin B-12. OBJECTIVE: The aim was to examine the relative impact of voluntary fortification and supplement use on dietary intakes and biomarker status of folate and vitamin B-12 in Irish adults. DESIGN: Folic acid and vitamin B-12 from fortified foods and supplements were estimated by using brand information for participants from the cross-sectional National Adult Nutrition Survey 2008-2010...
June 2015: American Journal of Clinical Nutrition
https://read.qxmd.com/read/24879926/risk-of-lymphoma-in-patients-with-inflammatory-bowel-disease-treated-with-azathioprine-and-6-mercaptopurine-a-meta-analysis
#37
JOURNAL ARTICLE
David S Kotlyar, James D Lewis, Laurent Beaugerie, Ann Tierney, Colleen M Brensinger, Javier P Gisbert, Edward V Loftus, Laurent Peyrin-Biroulet, Wojciech C Blonski, Manuel Van Domselaar, Maria Chaparro, Sandipani Sandilya, Meenakshi Bewtra, Florian Beigel, Livia Biancone, Gary R Lichtenstein
BACKGROUND & AIMS: Thiopurine therapy for inflammatory bowel disease (IBD) has been associated with increased risk for lymphoma. We estimated the relative risk of lymphoma in patients with IBD exposed to thiopurines and compared relative risk values derived from population-based studies with those from referral center-based studies. We investigated whether active use increased risk compared with past use, and whether sex, age, or duration of use affects risk of lymphoma. METHODS: We searched MEDLINE, EMBASE, and Cochrane databases, as well as conference abstracts and international publications, for the terms "6-MP and lymphoma," "6-mercaptopurine and lymphoma," "thiopurines and lymphoma," "azathioprine and cancer and IBD," "azathioprine and malignancy and IBD," "azathioprine and lymphoma," and "lymphoproliferative and thiopurines...
May 2015: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/25894530/sport-related-concussion-reporting-and-state-legislative-effects
#38
JOURNAL ARTICLE
Ashley A LaRoche, Lindsay D Nelson, Peter K Connelly, Kevin D Walter, Michael A McCrea
OBJECTIVE: To investigate concussion rates and reporting frequencies in high school and collegiate athletes in 2013, compare results to those obtained from 1999 to 2002, and examine to what extent the 2012 Wisconsin state concussion law affected reporting in 2013. DESIGN: Retrospective 2013 survey compared with prior survey. SETTING: High schools and colleges in the Milwaukee, Wisconsin, area. PARTICIPANTS: Athletes (N = 784) from multiple sports were surveyed in 2013...
January 2016: Clinical Journal of Sport Medicine
https://read.qxmd.com/read/18367735/rapid-disuse-atrophy-of-diaphragm-fibers-in-mechanically-ventilated-humans
#39
JOURNAL ARTICLE
Sanford Levine, Taitan Nguyen, Nyali Taylor, Michael E Friscia, Murat T Budak, Pamela Rothenberg, Jianliang Zhu, Rajeev Sachdeva, Seema Sonnad, Larry R Kaiser, Neal A Rubinstein, Scott K Powers, Joseph B Shrager
BACKGROUND: The combination of complete diaphragm inactivity and mechanical ventilation (for more than 18 hours) elicits disuse atrophy of myofibers in animals. We hypothesized that the same may also occur in the human diaphragm. METHODS: We obtained biopsy specimens from the costal diaphragms of 14 brain-dead organ donors before organ harvest (case subjects) and compared them with intraoperative biopsy specimens from the diaphragms of 8 patients who were undergoing surgery for either benign lesions or localized lung cancer (control subjects)...
March 27, 2008: New England Journal of Medicine
https://read.qxmd.com/read/25895715/intravenous-ketamine-to-facilitate-noninvasive-ventilation-in-a-patient-with-a-severe-asthma-exacerbation
#40
JOURNAL ARTICLE
Emeen Kiureghian, J Michael Kowalski
No abstract text is available yet for this article.
November 2015: American Journal of Emergency Medicine
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