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Endométrio

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7 papers 25 to 100 followers
By Alessandro Franciscon doctor
https://www.readbyqxmd.com/read/19574776/intravaginal-brachytherapy-in-figo-stage-i-low-risk-endometrial-cancer-a-controlled-randomized-study
#1
RANDOMIZED CONTROLLED TRIAL
Bengt Sorbe, Britta Nordström, Johanna Mäenpää, Janez Kuhelj, Dimitrij Kuhelj, Sait Okkan, Jean-Francois Delaloye, B Frankendal
The purpose of the study was to compare postoperative vaginal irradiation with surgery alone in low-risk International Federation of Gynecology and Obstetrics (FIGO) stage IA-IB endometrial carcinoma. The study was a prospective, randomized trial of 645 evaluable low-risk endometrial carcinoma patients from 6 European gynecologic cancer centers. All tumors were in FIGO stage IA-IB, of endometrioid histological type, and FIGO grade 1-2. High-dose-rate afterloading equipments (iridium [Ir] 192 or cobalt [co] 60) were used at 5 centers, and low-dose-rate (LDR) afterloading equipment (cesium [Cs] 137) at 1 center...
July 2009: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/26634381/esmo-esgo-estro-consensus-conference-on-endometrial-cancer-diagnosis-treatment-and-follow-up
#2
N Colombo, C Creutzberg, F Amant, T Bosse, A González-Martín, J Ledermann, C Marth, R Nout, D Querleu, M R Mirza, C Sessa
The first joint European Society for Medical Oncology (ESMO), European SocieTy for Radiotherapy & Oncology (ESTRO) and European Society of Gynaecological Oncology (ESGO) consensus conference on endometrial cancer was held on 11-13 December 2014 in Milan, Italy, and comprised a multidisciplinary panel of 40 leading experts in the management of endometrial cancer. Before the conference, the expert panel prepared three clinically relevant questions about endometrial cancer relating to the following four areas: prevention and screening, surgery, adjuvant treatment and advanced and recurrent disease...
January 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/26683800/esmo-esgo-estro-consensus-conference-on-endometrial-cancer-diagnosis-treatment-and-follow-up
#3
Nicoletta Colombo, Carien Creutzberg, Frederic Amant, Tjalling Bosse, Antonio González-Martín, Jonathan Ledermann, Christian Marth, Remi Nout, Denis Querleu, Mansoor Raza Mirza, Cristiana Sessa
The first joint European Society for Medical Oncology (ESMO), European SocieTy for Radiotherapy & Oncology (ESTRO) and European Society of Gynaecological Oncology (ESGO) consensus conference on endometrial cancer was held on 11-13 December 2014 in Milan, Italy, and comprised a multidisciplinary panel of 40 leading experts in the management of endometrial cancer. Before the conference, the expert panel prepared three clinically-relevant questions about endometrial cancer relating to the following four areas: Prevention and screening, surgery, adjuvant treatment and advanced and recurrent disease...
December 2015: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/24766678/the-role-of-postoperative-radiation-therapy-for-endometrial-cancer-executive-summary-of-an-american-society-for-radiation-oncology-evidence-based-guideline
#4
Ann Klopp, Benjamin D Smith, Kaled Alektiar, Alvin Cabrera, Antonio L Damato, Beth Erickson, Gini Fleming, David Gaffney, Kathryn Greven, Karen Lu, David Miller, David Moore, Daniel Petereit, Tracey Schefter, William Small, Catheryn Yashar, Akila N Viswanathan
PURPOSE: To present evidence-based guidelines for adjuvant radiation in the treatment of endometrial cancer. METHODS AND MATERIALS: Key clinical questions to be addressed in this evidence-based guideline on endometrial cancer were identified. A comprehensive literature review was performed to identify studies that included no adjuvant therapy, or pelvic radiation or vaginal brachytherapy with or without systemic chemotherapy. Outcomes included local control, survival rates, and overall assessment of quality of life...
May 2014: Practical Radiation Oncology
https://www.readbyqxmd.com/read/20206777/vaginal-brachytherapy-versus-pelvic-external-beam-radiotherapy-for-patients-with-endometrial-cancer-of-high-intermediate-risk-portec-2-an-open-label-non-inferiority-randomised-trial
#5
RANDOMIZED CONTROLLED TRIAL
R A Nout, V T H B M Smit, H Putter, I M Jürgenliemk-Schulz, J J Jobsen, L C H W Lutgens, E M van der Steen-Banasik, J W M Mens, A Slot, M C Stenfert Kroese, B N F M van Bunningen, A C Ansink, W L J van Putten, C L Creutzberg
BACKGROUND: After surgery for intermediate-risk endometrial carcinoma, the vagina is the most frequent site of recurrence. This study established whether vaginal brachytherapy (VBT) is as effective as pelvic external beam radiotherapy (EBRT) in prevention of vaginal recurrence, with fewer adverse effects and improved quality of life. METHODS: In this open-label, non-inferiority, randomised trial undertaken in 19 Dutch radiation oncology centres, 427 patients with stage I or IIA endometrial carcinoma with features of high-intermediate risk were randomly assigned by a computer-generated, biased coin minimisation procedure to pelvic EBRT (46 Gy in 23 fractions; n=214) or VBT (21 Gy high-dose rate in three fractions, or 30 Gy low-dose rate; n=213)...
March 6, 2010: Lancet
https://www.readbyqxmd.com/read/26150442/postoperative-radiation-therapy-for-endometrial-cancer-american-society-of-clinical-oncology-clinical-practice-guideline-endorsement-of-the-american-society-for-radiation-oncology-evidence-based-guideline
#6
Larissa A Meyer, Kari Bohlke, Matthew A Powell, Amanda N Fader, Gregg E Franklin, Larissa J Lee, Daniela Matei, Lourie Coallier, Alexi A Wright
PURPOSE: To provide guidance on the role of adjuvant radiation therapy in the treatment of endometrial cancer. METHODS: "The Role of Postoperative Radiation Therapy for Endometrial Cancer: An ASTRO Evidence-Based Guideline" by Klopp et al, published in 2014 in Practical Radiation Oncology, was reviewed for developmental rigor by methodologists. The American Society for Radiation Oncology (ASTRO) guideline content and recommendations were further reviewed by the American Society of Clinical Oncology (ASCO) Endorsement Panel...
September 10, 2015: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/21676554/external-pelvic-and-vaginal-irradiation-versus-vaginal-irradiation-alone-as-postoperative-therapy-in-medium-risk-endometrial-carcinoma-a-prospective-randomized-study
#7
RANDOMIZED CONTROLLED TRIAL
Bengt Sorbe, György Horvath, Håkan Andersson, Karin Boman, Caroline Lundgren, Birgitta Pettersson
PURPOSE: To evaluate the value of adjuvant external beam pelvic radiotherapy as adjunct to vaginal brachytherapy (VBT) in medium-risk endometrial carcinoma, with regard to locoregional tumor control, recurrences, survival, and toxicity. METHODS AND MATERIALS: Consecutive series of 527 evaluable patients were included in this randomized trial. Median follow-up for patients alive was 62 months. The primary study endpoints were locoregional recurrences and overall survival...
March 1, 2012: International Journal of Radiation Oncology, Biology, Physics
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