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Gastroenterology

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476 papers 1000+ followers
By Jeff Bank Internal Medicine R2 at the University of Utah
https://www.readbyqxmd.com/read/29134968/-weekend-effect-in-patients-with-upper-gastrointestinal-hemorrhage-a-systematic-review-and-meta-analysis
#1
REVIEW
Ashutosh Gupta, Rajender Agarwal, Ashwin N Ananthakrishnan
OBJECTIVES: "Weekend effect" refers to worse outcomes among patients presenting to the hospital on weekends or holidays. We performed a systematic review and meta-analysis of observational studies assessing the impact of the "weekend effect" in patients with upper gastrointestinal hemorrhage (UGIH). METHODS: We searched key bibliographic databases using keywords and MeSH terms related to gastrointestinal hemorrhage and "weekend effect". Our primary analysis evaluated mortality in patients with UGIH who were hospitalized on the weekend or after-hours compared with a weekday...
November 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29134969/the-prevalence-and-impact-of-overlapping-rome-iv-diagnosed-functional-gastrointestinal-disorders-on-somatization-quality-of-life-and-healthcare-utilization-a-cross-sectional-general-population-study-in-three-countries
#2
Imran Aziz, Olafur S Palsson, Hans Törnblom, Ami D Sperber, William E Whitehead, Magnus Simrén
OBJECTIVES: The population prevalence of Rome IV-diagnosed functional gastrointestinal disorders (FGIDs) and their cumulative effect on health impairment is unknown. METHODS: An internet-based cross-sectional health survey was completed by 5,931 of 6,300 general population adults from three English-speaking countries (2100 each from USA, Canada, and UK). Quota-based sampling was used to generate demographically balanced and population representative samples with regards to age, sex, and education level...
November 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29112202/adherence-to-a-healthy-lifestyle-is-associated-with-a-lower-risk-of-diverticulitis-among-men
#3
Po-Hong Liu, Yin Cao, Brieze R Keeley, Idy Tam, Kana Wu, Lisa L Strate, Edward L Giovannucci, Andrew T Chan
OBJECTIVES: Diverticulitis is a common disease with high clinical burden. We evaluated the joint contribution of multiple lifestyle factors to risks of incident diverticulitis. We also estimated the proportion of diverticulitis preventable by lifestyle modifications. METHODS: We prospectively examined the association between lifestyle factors (red meat, dietary fiber intake, vigorous physical activity (activity with metabolic equivalent ≥6), body mass index (BMI), and smoking) and risk of diverticulitis among participants in the Health Professionals Follow-Up Study...
November 7, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29100852/-spending-your-life-wisely-how-to-create-an-asset-management-plan
#4
Megan A Adams, John I Allen
No abstract text is available yet for this article.
October 31, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29087398/risk-of-clostridium-difficile-infection-in-patients-with-celiac-disease-a-population-based-study
#5
Benjamin Lebwohl, Yael R Nobel, Peter H R Green, Martin J Blaser, Jonas F Ludvigsson
OBJECTIVES: Patients with celiac disease are at increased risk for infections such as tuberculosis, influenza, and pneumococcal pneumonia. However, little is known about the incidence of Clostridium difficile infection (CDI) in patients with celiac disease. METHODS: We identified patients with celiac disease based on intestinal biopsies submitted to all pathology departments in Sweden over a 39-year period (from July 1969 through February 2008). We compared risk of CDI (based on stratified Cox proportional hazards models) among patients with celiac disease vs...
October 31, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29087399/proton-pump-inhibitor-therapy-for-eosinophilic-esophagitis-a-paradigm-shift
#6
Javier Molina-Infante, Alfredo J Lucendo
No abstract text is available yet for this article.
October 31, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29087400/colorectal-cancer-screening-in-the-non-syndromic-familial-risk-population-is-it-time-to-revise-the-clinical-guidelines
#7
Enrique Quintero, Antonio Z Gimeno-García
No abstract text is available yet for this article.
October 31, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29063908/adherence-to-mediterranean-diet-and-non-alcoholic-fatty-liver-disease-effect-on-insulin-resistance
#8
Francesco Baratta, Daniele Pastori, Licia Polimeni, Tommaso Bucci, Fabrizio Ceci, Cinzia Calabrese, Ilaria Ernesti, Gaetano Pannitteri, Francesco Violi, Francesco Angelico, Maria Del Ben
OBJECTIVES: The prevalence of cardiometabolic disorders, including non-alcoholic fatty liver disease (NAFLD), is increasing in western countries, because of changes in lifestyle and dietary habits. Mediterranean Diet (Med-Diet) is effective for cardiovascular prevention, but its relationship with NAFLD has been scarcely investigated. METHODS: We included 584 consecutive outpatients presenting with one or more cardiovascular risk factor such as type 2 diabetes mellitus (T2DM), arterial hypertension, overweight/obesity, and dyslipidemia...
October 24, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29039850/systematic-review-disease-activity-indices-in-eosinophilic-esophagitis
#9
REVIEW
Marijn J Warners, Pieter Hindryckx, Barrett G Levesque, Claire E Parker, Lisa M Shackelton, Reena Khanna, William J Sandborn, Geert R D'Haens, Brian G Feagan, Albert J Bredenoord, Vipul Jairath
OBJECTIVES: There is no clear consensus regarding the most appropriate measure(s) of eosinophilic esophagitis (EoE) disease activity. We aimed to identify all scoring indices used for the measurement of disease activity in EoE, appraise their operating properties, and discuss their value as outcome measures. METHODS: MEDLINE, EMBASE, and CENTRAL (The Cochrane library) were searched from inception to 11 May 2016. Randomized controlled trials (RCTs), cohort, case-control, and cross-sectional studies that reported outcomes to measure EoE disease activity or response to treatment were eligible...
November 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29016565/colonoscopy-vs-fecal-immunochemical-test-in-reducing-mortality-from-colorectal-cancer-confirm-rationale-for-study-design
#10
Jason A Dominitz, Douglas J Robertson, Dennis J Ahnen, James E Allison, Margaret Antonelli, Kathy D Boardman, Maria Ciarleglio, Barbara J Del Curto, Grant D Huang, Thomas F Imperiale, Meaghan F Larson, David Lieberman, Theresa O'Connor, Timothy J O'Leary, Peter Peduzzi, Dawn Provenzale, Aasma Shaukat, Shahnaz Sultan, Amy Voorhees, Robert Wallace, Peter D Guarino
RATIONALE: Colorectal cancer (CRC) is preventable through screening, with colonoscopy and fecal occult blood testing comprising the two most commonly used screening tests. Given the differences in complexity, risk, and cost, it is important to understand these tests' comparative effectiveness. STUDY DESIGN: The CONFIRM Study is a large, pragmatic, multicenter, randomized, parallel group trial to compare screening with colonoscopy vs. the annual fecal immunochemical test (FIT) in 50,000 average risk individuals...
November 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29031502/low-rates-of-gastrointestinal-and-non-gastrointestinal-complications-for-screening-or-surveillance-colonoscopies-in-a-population-based-study
#11
Wang Louise, Mannalithara Ajitha, Singh Gurkirpal, Ladabaum Uri
BACKGROUND: The full spectrum of serious non-gastrointestinal (non-GI) post-colonoscopy complications has not been well characterized. We analyzed rates of and factors associated with adverse post-colonoscopy GI and non-GI events (cardiovascular, pulmonary, or infectious) attributable to screening or surveillance colonoscopy (S-colo) and non-screening or non-surveillance colonoscopy (NS-colo). METHODS: We performed a population-based study of colonoscopy complications using databases from California hospital-owned and nonhospital-owned ambulatory facilities, emergency departments, and hospitals from January 1, 2005 through December 31, 2011...
October 11, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29031793/the-role-of-anchoring-in-working-up-diarrhea-a-practical-teaching-case
#12
Claire L Jansson-Knodell, Sahil Khanna
No abstract text is available yet for this article.
October 12, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28972596/population-based-paternity-rate-and-partner-birth-outcomes-among-utah-men-with-inflammatory-bowel-disease
#13
Luke Martin, William Peche, Kathryn Peterson, Yuan Wan, Stephanie Chan, Ryan Morton, Chong Zhang, Angela P Presson, James Hotaling
OBJECTIVES: Crohn's disease (CD) and ulcerative colitis (UC) impact an estimated 350,000 reproductive age men in the United States. The reproductive consequences are largely unknown. The objective of this study was to evaluate the effects of CD and UC on reproductive outcomes. METHODS: From the Utah Population Database, we identified a cohort of male patients with CD (1,245) and UC (1,368). Male-sibling controls were identified, and birth outcome data from offspring were obtained...
November 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28886962/endoscopy-in-inflammatory-bowel-disease-advances-in-disease%C3%A2-management
#14
REVIEW
Elizabeth A Scoville, David A Schwartz
No abstract text is available yet for this article.
December 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28925988/how-i-approach-it-care-of-the-post-ablation-barrett-s-esophagus-patient
#15
Shervin Shafa, Nicholas J Shaheen
No abstract text is available yet for this article.
October 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28925989/development-of-a-symptom-focused-patient-reported-outcome-measure-for-functional-dyspepsia-the-functional-dyspepsia-symptom-diary-fdsd
#16
Fiona Taylor, Sophie Higgins, Robyn T Carson, Sonya Eremenco, Catherine Foley, Brian E Lacy, Henry P Parkman, David S Reasner, Alan L Shields, Jan Tack, Nicholas J Talley
OBJECTIVES: The Functional Dyspepsia Symptom Diary (FDSD) was developed to address the lack of symptom-focused, patient-reported outcome (PRO) measures designed for use in functional dyspepsia (FD) patients and meeting Food and Drug Administration recommendations for PRO instrument development. METHODS: Concept elicitation interviews were conducted with FD participants to identify symptoms important and relevant to FD patients. A preliminary version of the FDSD was constructed, then completed by FD participants on an electronic device in cognitive interviews to evaluate the readability, comprehensibility, relevance, and comprehensiveness of the FDSD, and to preliminarily evaluate its measurement properties...
September 19, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28838972/acute-pancreatitis-recent-advances-through-randomised-trials
#17
REVIEW
Sven M van Dijk, Nora D L Hallensleben, Hjalmar C van Santvoort, Paul Fockens, Harry van Goor, Marco J Bruno, Marc G Besselink
Acute pancreatitis is one of the most common GI conditions requiring acute hospitalisation and has a rising incidence. In recent years, important insights on the management of acute pancreatitis have been obtained through numerous randomised controlled trials. Based on this evidence, the treatment of acute pancreatitis has gradually developed towards a tailored, multidisciplinary effort, with distinctive roles for gastroenterologists, radiologists and surgeons. This review summarises how to diagnose, classify and manage patients with acute pancreatitis, emphasising the evidence obtained through randomised controlled trials...
November 2017: Gut
https://www.readbyqxmd.com/read/28847751/effects-of-mongersen-ged-0301-on-endoscopic-and-clinical-outcomes-in-patients-with-active-crohn-s-disease
#18
Brian G Feagan, Bruce E Sands, Guillermo Rossiter, Xiaobin Li, Keith Usiskin, Xiaojiang Zhan, Jean-Frédéric Colombel
GED-0301 is an antisense oligodeoxynucleotide with a sequence complementary to the Smad7 mRNA transcript. Smad7 is a negative regulator of transforming growth factor-β, which is increased in the intestinal mucosa of patients with active Crohn's disease (CD). We randomly assigned 63 CD patients to 4-, 8-, or 12-week treatment groups receiving oral GED-0301 (160 mg/day). The primary objective was to determine GED-0301's effect on endoscopic CD measures; secondary objectives included effects on clinical activity...
August 25, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28802875/primary-sclerosing-cholangitis-a-comprehensive-review
#19
REVIEW
Tom H Karlsen, Trine Folseraas, Douglas Thorburn, Mette Vesterhus
Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct strictures and progressive liver disease. Inflammatory bowel disease is usually present and there is a high risk of cholangiocarcinoma and colorectal cancer. Most patients ultimately require liver transplantation, after which disease recurrence may occur. With limited therapeutic options and a lack of proven surveillance strategies, patients currently have significant unmet needs. In the present seminar, we provide a comprehensive review of the status of the field...
August 10, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28809386/complications-of-bariatric-surgery-what-you-can-expect-to-see-in-your-gi-practice
#20
REVIEW
Allison R Schulman, Christopher C Thompson
Obesity is one of the most significant health problems worldwide. Bariatric surgery has become one of the fastest growing operative procedures and has gained acceptance as the leading option for weight-loss. Despite improvement in the performance of bariatric surgical procedures, complications are not uncommon. There are a number of unique complications that arise in this patient population and require specific knowledge for proper management. Furthermore, conditions unrelated to the altered anatomy typically require a different management strategy...
November 2017: American Journal of Gastroenterology
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