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By Vicente Bebia OB/GYN Residente Hospital 12 de Octubre, Madrid
https://www.readbyqxmd.com/read/26363481/transvaginal-cervical-length-scans-to-prevent-prematurity-in-twins-a-randomized-controlled-trial
#1
RANDOMIZED CONTROLLED TRIAL
Michael C Gordon, David S McKenna, Theresa L Stewart, Bobby C Howard, Kimberly F Foster, Kenneth Higby, Rebecca L Cypher, William H Barth
BACKGROUND: Twin pregnancies are associated with an increased risk of perinatal morbidity and mortality primarily due to spontaneous preterm deliveries. The mean gestational age for delivery is 35.3 weeks and twins account for 23% of preterm births <32 weeks. A number of strategies have been proposed to prevent preterm deliveries: tocolytics, bed rest, hospitalization, home uterine activity monitoring, cerclage, and most recently, progesterone. Unfortunately, none have proven effective...
February 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/25797233/vaginal-progesterone-for-maintenance-tocolysis-a-systematic-review-and-metaanalysis-of-randomized-trials
#2
REVIEW
Anju Suhag, Gabriele Saccone, Vincenzo Berghella
OBJECTIVE: We sought to evaluate the efficacy of maintenance tocolysis with vaginal progesterone compared to control (placebo or no treatment) in singleton gestations with arrested preterm labor (PTL) in a metaanalysis of randomized controlled trials. STUDY DESIGN: Searches were performed in MEDLINE, OVID, Scopus, ClinicalTrials.gov, and the Cochrane Central Register of Controlled Trials with the use of a combination of key words and text words related to "progesterone," "tocolysis," and "preterm labor" from 1966 through November 2014...
October 2015: American Journal of Obstetrics and Gynecology
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