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Fibromyalgia

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2 papers 0 to 25 followers
https://www.readbyqxmd.com/read/25841257/neuropathic-pain-principles-of-diagnosis-and-treatment
#1
REVIEW
Ian Gilron, Ralf Baron, Troels Jensen
Neuropathic pain is caused by disease or injury of the nervous system and includes various chronic conditions that, together, affect up to 8% of the population. A substantial body of neuropathic pain research points to several important contributory mechanisms including aberrant ectopic activity in nociceptive nerves, peripheral and central sensitization, impaired inhibitory modulation, and pathological activation of microglia. Clinical evaluation of neuropathic pain requires a thorough history and physical examination to identify characteristic signs and symptoms...
April 2015: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/24737367/fibromyalgia-a-clinical-review
#2
REVIEW
Daniel J Clauw
IMPORTANCE: Fibromyalgia is present in as much as 2% to 8% of the population, is characterized by widespread pain, and is often accompanied by fatigue, memory problems, and sleep disturbances. OBJECTIVE: To review the epidemiology, pathophysiology, diagnosis, and treatment of fibromyalgia. EVIDENCE REVIEW: The medical literature on fibromyalgia was reviewed from 1955 to March 2014 via MEDLINE and the Cochrane Central Registry of Controlled Trials, with an emphasis on meta-analyses and contemporary evidence-based treatment guidelines...
April 16, 2014: JAMA: the Journal of the American Medical Association
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