Read by QxMD icon Read

Intervertebral disc

shared collection
9 papers 0 to 25 followers
Julio Urrutia, Tomas Zamora, Carlos Prada
PURPOSE: Several studies using magnetic resonance imaging (MRI) to evaluate the lumbar spine in adults have shown a large prevalence of degenerative changes in asymptomatic subjects; however, studies in pediatric patients are scarce. Those studies have suggested a lower rate of degenerative findings in adolescents than in adults, but the actual prevalence of MRI findings in the pediatric population has not yet been determined. We aimed to determine the prevalence of degenerative changes in the lumbar spine of pediatric patients using abdominal and pelvic MRI as the screening tool...
February 2016: European Spine Journal
Mark J Hancock, Chris M Maher, Peter Petocz, Chung-Wei Christine Lin, Daniel Steffens, Alejandro Luque-Suarez, John S Magnussen
BACKGROUND CONTEXT: The clinical importance of lumbar pathology identified on magnetic resonance imaging (MRI) remains unclear. It is plausible that pathology seen on MRI is a risk factor for a recurrence of low back pain (LBP); however, to our knowledge, this has not been investigated by previous studies. PURPOSE: The aim was to investigate whether lumbar pathology, identifiable on MRI, increases the risk of a recurrence of LBP. STUDY DESIGN: This was a prospective inception cohort study with 1-year follow-up...
November 1, 2015: Spine Journal: Official Journal of the North American Spine Society
Bodil Arnbak, Tue S Jensen, Niels Egund, Anna Zejden, Kim Hørslev-Petersen, Claus Manniche, Anne G Jurik
OBJECTIVE: To estimate the prevalence of degenerative and spondyloarthritis (SpA)-related magnetic resonance imaging (MRI) findings in the spine and sacroiliac joints (SIJs) and analyse their association with gender and age in persistent low back pain (LBP) patients. METHODS: Degenerative and SpA-related MRI findings in the whole spine and SIJs were evaluated in Spine Centre patients aged 18-40 years with LBP. RESULTS: Among the 1,037 patients, the prevalence of disc degeneration, disc contour changes and vertebral endplate signal (Modic) changes were 87 % (±SEM 1...
April 2016: European Radiology
Pierre Boucher, Sébastien Robidoux
The purpose of this review is to expand practitioners' knowledge on areas of liability when treating low back pain patients. Six cases where chiropractors in Canada were sued for allegedly causing or aggravating lumbar disc herniation after spinal manipulative therapy were retrieved using the CANLII search database. The case series involves 4 men and 2 women with an average age of 37.3 years (range, 31-48 years). Trial courts' decisions were rendered between 2000 and 2011. This study highlights the following conclusions from Canadian courts: 1) informed consent is an ongoing process that cannot be entirely delegated to office personnel; 2) when the patient's history reveals risk factors for lumbar disc herniation the chiropractor has the duty to rule out disc pathology as an etiology for the symptoms presented by the patients before beginning anything but conservative palliative treatment; 3) lumbar disc herniation may be triggered by spinal manipulative therapy on vertebral segments distant from the involved herniated disc such as the thoracic spine...
February 2014: Journal of Forensic and Legal Medicine
Thijs Grunhagen, Aboulfazl Shirazi-Adl, Jeremy C T Fairbank, Jill P G Urban
The biomechanical behavior of the intervertebral disk ultimately depends on the viability and activity of a small population of resident cells that make and maintain the disk's extracellular matrix. Nutrients that support these cells are supplied by the blood vessels at the disks' margins and diffuse through the matrix of the avascular disk to the cells. This article reviews pathways of nutrient supply to these cells; examines factors that may interrupt these pathways, and discusses consequences for disk cell survival, disk degeneration, and disk repair...
October 2011: Orthopedic Clinics of North America
S Rajasekaran, J Naresh Babu, R Arun, B Roy Wilson Armstrong, Ajoy Prasad Shetty, Subramaniam Murugan
STUDY DESIGN: An in vivo serial magnetic resonance imaging study of diffusion characteristics in human lumbar discs over 24 hours in healthy volunteers and patients with low back pain. OBJECTIVES: To document the temporal pattern of diffusion in normal human lumbar discs and to study the influence of the vascularity of bone and the status of endplate on diffusion in the normal and degenerate discs. SUMMARY OF BACKGROUND DATA: Diffusion is the only source of nutrition to the discs, but no firm data are available on pattern of diffusion in humans...
December 1, 2004: Spine
A J Freemont, A Watkins, C Le Maitre, P Baird, M Jeziorska, M T N Knight, E R S Ross, J P O'Brien, J A Hoyland
Following a previous description of nociceptive nerve fibre growth into usually aneural inner parts of painful intervertebral disc (IVD), this study has investigated whether nociceptive nerve ingrowth into painful IVD is stimulated by local production of neurotrophins. Immunohistochemistry and in situ hybridization have been used to investigate expression of the candidate neurotrophin, nerve growth factor (NGF), and its high- and low-affinity receptors trk-A and p75, respectively, in painful IVD excised for the management of low back pain...
July 2002: Journal of Pathology
Tiffany Kadow, Gwendolyn Sowa, Nam Vo, James D Kang
BACKGROUND: Intervertebral disc degeneration is a common condition with few inexpensive and effective modes of treatment, but current investigations seek to clarify the underlying process and offer new treatment options. It will be important for physicians to understand the molecular basis for the pathology and how it translates to developing clinical treatments for disc degeneration. In this review, we sought to summarize for clinicians what is known about the molecular processes that causes disc degeneration...
June 2015: Clinical Orthopaedics and related Research
Christopher K Kepler, Ravi K Ponnappan, Chadi A Tannoury, Marakand V Risbud, David G Anderson
BACKGROUND: Intervertebral disc (IVD) degeneration remains a clinically important condition for which treatment is costly and relatively ineffective. The molecular basis of degenerative disc disease has been an intense focus of research recently, which has greatly increased our understanding of the biology underlying this process. PURPOSE: To review the current understanding of the molecular basis of disc degeneration. STUDY DESIGN: Review article...
March 2013: Spine Journal: Official Journal of the North American Spine Society
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"