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Steroid in viral wheeze of preschool children

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By Dr Faisal Aijaz Emergency medicine Registrar.
Jayachandran Panickar, Monica Lakhanpaul, Paul C Lambert, Priti Kenia, Terence Stephenson, Alan Smyth, Jonathan Grigg
BACKGROUND: Attacks of wheezing induced by upper respiratory viral infections are common in preschool children between the ages of 10 months and 6 years. A short course of oral prednisolone is widely used to treat preschool children with wheezing who present to a hospital, but there is conflicting evidence regarding its efficacy in this age group. METHODS: We conducted a randomized, double-blind, placebo-controlled trial comparing a 5-day course of oral prednisolone (10 mg once a day for children 10 to 24 months of age and 20 mg once a day for older children) with placebo in 700 children between the ages of 10 months and 60 months...
January 22, 2009: New England Journal of Medicine
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