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By Jason Mann No BS pulmonary critical care fellow
https://www.readbyqxmd.com/read/27589411/permissive-underfeeding-or-standard-enteral-feeding-in-high-and-low-nutritional-risk-critically-ill-adults-post-hoc-analysis-of-the-permit-trial
#1
Yaseen M Arabi, Abdulaziz S Aldawood, Hasan M Al-Dorzi, Hani M Tamim, Samir H Haddad, Gwynne Jones, Lauralyn McIntyre, Othman Solaiman, Maram H Sakkijha, Musharaf Sadat, Shihab Mundekkadan, Anand Kumar, Sean M Bagshaw, Sangeeta Mehta
RATIONALE: The optimal nutritional strategy for critically ill adults at high nutritional risk is unclear. OBJECTIVE: In patients with different baseline nutritional risk, we examined the effect of permissive underfeeding with full protein intake compared to standard feeding on 90-day mortality. METHODS: This is a post-hoc analysis of the PermiT (Permissive Underfeeding versus Target Enteral Feeding in Adult Critically Ill Patients) trial...
September 2, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/25992505/permissive-underfeeding-or-standard-enteral-feeding-in-critically-ill-adults
#2
RANDOMIZED CONTROLLED TRIAL
Yaseen M Arabi, Abdulaziz S Aldawood, Samir H Haddad, Hasan M Al-Dorzi, Hani M Tamim, Gwynne Jones, Sangeeta Mehta, Lauralyn McIntyre, Othman Solaiman, Maram H Sakkijha, Musharaf Sadat, Lara Afesh
BACKGROUND: The appropriate caloric goal for critically ill adults is unclear. We evaluated the effect of restriction of nonprotein calories (permissive underfeeding), as compared with standard enteral feeding, on 90-day mortality among critically ill adults, with maintenance of the full recommended amount of protein in both groups. METHODS: At seven centers, we randomly assigned 894 critically ill adults with a medical, surgical, or trauma admission category to permissive underfeeding (40 to 60% of calculated caloric requirements) or standard enteral feeding (70 to 100%) for up to 14 days while maintaining a similar protein intake in the two groups...
June 18, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/25271389/trial-of-the-route-of-early-nutritional-support-in-critically-ill-adults
#3
RANDOMIZED CONTROLLED TRIAL
Sheila E Harvey, Francesca Parrott, David A Harrison, Danielle E Bear, Ella Segaran, Richard Beale, Geoff Bellingan, Richard Leonard, Michael G Mythen, Kathryn M Rowan
BACKGROUND: Uncertainty exists about the most effective route for delivery of early nutritional support in critically ill adults. We hypothesized that delivery through the parenteral route is superior to that through the enteral route. METHODS: We conducted a pragmatic, randomized trial involving adults with an unplanned admission to one of 33 English intensive care units. We randomly assigned patients who could be fed through either the parenteral or the enteral route to a delivery route, with nutritional support initiated within 36 hours after admission and continued for up to 5 days...
October 30, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/25251763/feeding-the-critically-ill-patient
#4
REVIEW
Stephen A McClave, Robert G Martindale, Todd W Rice, Daren K Heyland
OBJECTIVE: Critically ill patients are usually unable to maintain adequate volitional intake to meet their metabolic demands. As such, provision of nutrition is part of the medical care of these patients. This review provides detail and interpretation of current data on specialized nutrition therapy in critically ill patients, with focus on recently published studies. DATA SOURCES: The authors used literature searches, personal contact with critical care nutrition experts, and knowledge of unpublished data for this review...
December 2014: Critical Care Medicine
https://www.readbyqxmd.com/read/24296860/enteral-nutrition-in-the-critically-ill-myths-and-misconceptions
#5
REVIEW
Paul E Marik
BACKGROUND: Nutritional support is an essential component of the management of critically ill and injured ICU patients. Optimal provision of calories and protein has been demonstrated to reduce morbidity, mortally, and length of ICU and hospital stay. Yet, a large proportion of ICU patients receive inadequate nutrition. OBJECTIVE: To provide an evidence-base assessment of factors leading to inadequate enteral nutrition support in critically ill patients. DATA SOURCE: Search of PubMed database and manual review of bibliographies from selected articles...
April 2014: Critical Care Medicine
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