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JOURNAL ARTICLE
C Adam Banks, Juliet Blakeslee-Carter, Veronica Nkie, Emily L Spangler, Shasha A Still, Kyle W Eudailey, Samuel K McElwee, Margaret S Blood, Zdenek Novak, Adam W Beck
BACKGROUND: Vascular complications (VC) associated with Extracorporeal Membrane Oxygenation (ECMO) during index hospitalization are prevalent and associated with increased mortality. Few studies have evaluated late VC following ECMO; this study aims to assess occurrence and management practices of late VC following discharge. METHODS: A retrospective single-institution review was performed of all patients surviving initial hospitalization after being cannulated for central or peripheral veno-venous (VV) or veno-arterial (VA) ECMO between January 1st 2019 and December 31st 2020...
April 22, 2024: Journal of Vascular Surgery
#2
JOURNAL ARTICLE
Kaiyi Peng, Linhui Hu, Xiangwei Huang, Yuemei He, Xinxin Wu, Huihua Li, Wentao Zhang, Hengling Zhu, Zheng Wang, Chunbo Chen
No previous studies have reported the use of a percutaneous suture technique performed by bedside intensivists for site closure during decannulation without direct artery repair in venoarterial extracorporeal membrane oxygenation (VA-ECMO) cases. Thus, the objective of this study was to evaluate the safety and effectiveness of this alternative approach. This retrospective study included 26 consecutive patients who underwent percutaneous VA-ECMO decannulation at Maoming People's Hospital. Bedside percutaneous suture technique performed by intensivists facilitated cannula site closure...
April 5, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
#3
JOURNAL ARTICLE
D Ramzy, F Esmailian, D Emerson, D Megna, R Levine, R Cole, E Passano, C Runyan, A Velleca, J Kobashigawa, J Moriguchi
PURPOSE: October 2018 saw a change in the UNOS heart allocation which prioritized the sickest patients especially those of temporary devices. The main driver of the change was to reduce wait list mortality. We aim to examine whether the new allocation benefits come at a cost of reduced post-transplant survival. METHODS: A retrospective UNOS database review of all heart transplants performed between April 2018 and April 2019 (n=3431). These patients divided according to their allocation status and whether they were done prior (n=2143) or after the allocation change (n=1288)...
April 2020: Journal of Heart and Lung Transplantation
#4
JOURNAL ARTICLE
Guillaume Coutance, Nicolas Jacob, Pierre Demondion, Lee S Nguyen, Adrien Bouglé, Nicolas Bréchot, Shaida Varnous, Pascal Leprince, Alain Combes, Guillaume Lebreton
OBJECTIVES: Heart transplantation in patients supported by venoarterial extracorporeal membrane oxygenation has been associated with poor prognosis. A specific protocol for extracorporeal membrane oxygenation management encompassing patient selection, implantation strategy, and preoperative and perioperative treatment is applied at our institution. Our aim was to compare posttransplant outcomes of patients supported or not by extracorporeal membrane oxygenation at the time of heart transplantation...
December 23, 2019: Critical Care Medicine
#5
JOURNAL ARTICLE
Raquel López-Vilella, Ignacio Sánchez-Lázaro, Azucena Pajares Moncho, Mónica Talavera Peregrina, Manuel Pérez Guillén, Iratxe Zarragoikoetxea Jáuregui, Ricardo Gimeno Costa, Víctor Donoso Trenado, Luis Martínez Dolz, Salvador Torregrosa Puerta, Luis Almenar Bonet
BACKGROUND: The purpose of this study was to compare early and late survival among patients who have undergone heart transplantation (HTx) with a short-term mechanical assist device. METHODS: This was an ambispective, single-center, consecutive study of patients undergoing urgent HTx for 5 years. Pediatric transplants, retransplants, and combined transplants were excluded. Forty-five patients were included. Four groups were analyzed: those with venoarterial extracorporeal membrane oxygenation (ECMO) implanted <10 days before HTx; those with ECMO implanted for >10 days; patients classified as INTERMACS 2 to 3 with Levitronix Centrimag implanted; and those classified as INTERMACS 2 with Levitronix Centrimag implanted...
November 2021: Transplantation Proceedings
#6
JOURNAL ARTICLE
M Kawabori, A C Critsinelis, T Nordan, F Y Chen, A Vest, M S Kiernan, D DeNofrio, G S Couper
PURPOSE: Preoptimizing the hemodynamics and volume status prior to heart transplant is essential for the outcome. Temporary mechanical circulatory support (MCS) has been expanding especially after recent changes to the UNOS donor heart allocation criteria. The aim of our study is to evaluate the incidence of various MCS device use and outcomes of preoperative MCS to heart transplantation. METHODS: We performed a retrospective analysis using the UNOS Resistry of all adult heart transplant recipients from 1997 to 2017 comparing various MCS device regarding days to discharge, hospital survival and 2 year survival rates...
April 2020: Journal of Heart and Lung Transplantation
#7
REVIEW
Kevin John John, Christoph G S Nabzdyk, Haval Chweich, Ajay Kumar Mishra, Amos Lal
The ProtekDuo (LivaNova, London, UK) cannula is a dual-lumen device, typically inserted into the right internal jugular (IJ) vein through a percutaneous approach, with fluoroscopy or ultrasound guidance. When connected to a pump, such as the TandemHeart (LivaNova, London, UK) or CentriMag (Abbott, Pleasanton, CA, USA), it can function as a right ventricular (RV) mechanical circulatory support (MCS). When an oxygenator is also added [veno-pulmonary (V-P)], it can provide extracorporeal membrane oxygenation (ECMO) support...
February 1, 2024: Annals of Translational Medicine
#8
JOURNAL ARTICLE
Sophie Paddock, James Meng, Nicholas Johnson, Rahul Chattopadhyay, Vasiliki Tsampasian, Vassilios Vassiliou
AIMS: Cardiogenic shock remains the leading cause of death in patients hospitalized with acute myocardial infarction. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used in the treatment of infarct-related cardiogenic shock. However, there is limited evidence regarding its beneficial impact on mortality. The aim of this study was to systematically review studies reporting the impact of VA-ECMO on mortality in patients with acute myocardial infarction complicated by cardiogenic shock...
January 2024: Eur Heart J Open
#9
JOURNAL ARTICLE
John Kuckelman, Phil Coffey, Musa Sharkawi, Caryl Bailey, Evan Hiner, Vijay Patel
Left ventricular (LV) unloading has been shown to improve survival for patients requiring veno-arterial extracorporeal membrane oxygenation (VA ECMO) support for cardiogenic shock. A mortality benefit has been shown for ECMO and concomitant placement of a transcatheter unloading LV pump such as an Impella device (colloquially referred to as ECPELLA or ECMELLA) for patients resuscitated with VA ECMO after a short period of cardiac arrest. Despite the described benefit of LV unloading with VA ECMO for cardiopulmonary resuscitation, it remains unclear as to what criteria should be used and what other diagnostic and therapeutic adjuncts may be useful...
January 25, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
#10
JOURNAL ARTICLE
Alexander M Bernhardt, Evgenij Potapov, Christophe Vandenbriele, Carsten Skurk, Letizia F Bertoldi, Federico Pappalardo
Cardiogenic shock (CS) is a life-threatening condition characterized by a state of inadequate systemic tissue perfusion caused by cardiac dysfunction. When to implement, change, or remove the use of a temporary mechanical circulatory support (tMCS) in patients with CS is dependent on the aetiology and severity. Here, patient scenarios underlying the need to escalate, de-escalate, wean, or bridge from tMCS devices are taken into consideration by interdisciplinary heart failure and CS teams. This includes a comprehensive review of and focus on the rationale for specific device escalation and de-escalation strategies, device selection, and general management...
December 2023: European Heart Journal Supplements: Journal of the European Society of Cardiology
#11
JOURNAL ARTICLE
Paolo Meani, Giacomo Veronese, Serena Todaro, Giuseppe Marchese, Giulio M Mondellini, Ilaria Protti, Blanca Martinez-Lopez de Arroyabe, Francesco Epis, Federico Pappalardo, Giovanna Pedrazzini, Christopher Munch, Vito Margari, Lorenzo Grazioli, Ferdinando Luca Lorini, Sergio Cattaneo, Andrea Montisci, Andrea Ballotta, Giuseppe Maria Raffa, Pietro Carboni, Matteo Lucchelli, Leonello Avalli, Luciano Babuin, Mirko Belliato, Pietro Bertini, Fabio Guarracino, Gianluca Paternoster, Valentina Ajello, Emanuele Catena, Sabino Scolletta, Federico Franchi, Andrea Musazzi, Davide Pacini, Fabio Sangalli, Matteo Attisani, Mauro Rinaldi, Giacomo Grasselli, Michele Mondino, Marco Ranucci, Roberto Lorusso
No abstract text is available yet for this article.
November 30, 2023: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
#12
JOURNAL ARTICLE
Medhat Radwan, Karim Baghdadi, Aron Frederik Popov, Rodrigo Sandoval Boburg, Petar Risteski, Christian Schlensak, Thomas Walter, Rafal Berger, Fabian Emrich
Background and Objectives : To analyze the patient outcome and complication rate of axillary artery cannulation for veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients who could not be weaned from cardiopulmonary bypass after cardiothoracic surgery. Materials and Methods: We analyzed the data of 179 patients who were supported with VA-ECMO with femoral-axillary access (FA VA-ECMO) after cardiothoracic surgery between January 2014 and January 2019 in our department. Patients requiring central aortic cannulation and patients with respiratory failure requiring veno-venous ECMO were excluded...
November 20, 2023: Medicina
#13
JOURNAL ARTICLE
Dirk von Lewinski, Lukas Herold, Eva Bachl, Heiko Bugger, Theresa Glantschnig, Ewald Kolesnik, Nicolas Verheyen, Martin Benedikt, Markus Wallner, Friederike von Lewinski, Albrecht Schmidt, Stefan Harb, Klemens Ablasser, Michael Sacherer, Daniel Scherr, Martin Manninger-Wünscher, Sascha Pätzold, Johannes Gollmer, Andreas Zirlik, Gabor G Toth
BACKGROUND: Cardiogenic shock (CS) exhibits high (~50%) in-hospital mortality. The recently published Extracorporeal life Support in Cardiogenic Shock (ECLS-SHOCK) trial demonstrated the neutral effects of the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) on all-cause death, as well as on all secondary outcomes in subjects presenting with myocardial-infarction (MI)-related CS. Here, we compared ECLS-SHOCK eligibility criteria with a real-world cohort of CS patients...
November 8, 2023: Journal of Clinical Medicine
#14
MULTICENTER STUDY
Joo Hee Jeong, Hyungdon Kook, Seung Hun Lee, Hyung Joon Joo, Jae Hyoung Park, Soon Jun Hong, Mi-Na Kim, Seong-Mi Park, Jae Seung Jung, Jeong Hoon Yang, Hyeon-Cheol Gwon, Chul-Min Ahn, Woo Jin Jang, Hyun-Joong Kim, Jang-Whan Bae, Sung Uk Kwon, Wang Soo Lee, Jin-Ok Jeong, Sang-Don Park, Seong-Hoon Lim, Cheol Woong Yu
Limited knowledge exists regarding the predictors of mortality after successful weaning of venoarterial extracorporeal membrane oxygenation (ECMO). We aimed to identify predictors of in-hospital mortality in patients with cardiogenic shock (CS) after successful weaning from ECMO. Data were obtained from a multicenter registry of CS. Successful ECMO weaning was defined as survival with minimal mean arterial pressure (> 65 mmHg) for > 24 h after ECMO removal. The primary outcome was in-hospital mortality after successful ECMO weaning...
October 16, 2023: Scientific Reports
#15
REVIEW
Shu Tang, Liqing Xu, Hui Li, Zhanshen Wu, Qiang Wen
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is a vital technique for severe respiratory or heart failure patients. Bleeding and thrombotic events are common during ECMO and negatively impact patient outcomes. Unfractionated heparin is the primary anticoagulant, but its adverse effects limit its use, necessitating alternative anticoagulants. OBJECTIVE: Review available alternative anticoagulants for adult ECMO patients. Explore potential novel anticoagulants for future ECMO use...
December 2023: European Journal of Clinical Pharmacology
#16
JOURNAL ARTICLE
Christopher Gaisendrees, Jan-Steffen Pooth, Maximilian Luehr, Anton Sabashnikov, Demetris Yannopoulos, Thorsten Wahlers
BACKGROUND: Around the world, survival rates after cardiac arrest range between <14% for inhospital (IHCA) and <10% for out-of-hospital cardiac arrest (OHCA). This situation could potentially be improved by using extracorporeal membrane oxygenation (ECMO) during cardiopulmonary resuscitation (CPR), i.e. by extracorporeal cardiopulmonary resuscitation (ECPR). METHODS: A selective literature search of Pubmed and Embase using the searching string ((ECMO) OR (ECLS)) AND (ECPR)) was carried out in February 2023 to prepare an up-todate review of published trials comparing the outcomes of ECPR with those of conventional CPR...
October 20, 2023: Deutsches Ärzteblatt International
#17
JOURNAL ARTICLE
Atsuyuki Watanabe, Aaqib Malik, Tadao Aikawa, Alexandros Briasoulis, Toshiki Kuno
Extracorporeal membrane oxygenation (ECMO) has been used for COVID-19-associated acute respiratory distress syndrome (ARDS). We aimed to elucidate the association between ECMO and mortality in patients with COVID-19-associated ARDS in the nationwide setting. United States National Inpatient Sample was used to identify mechanically ventilated adults for COVID-19 with ARDS. We divided them into three groups according to the use of ECMO (i.e., no-ECMO, venovenous [VV]-ECMO, and venoarterial [VA]-ECMO). The primary outcome was in-hospital mortality, while the secondary outcomes included the length of hospital stay (LOS) and the total costs during hospitalization...
July 2023: Journal of Medical Virology
#18
MULTICENTER STUDY
Silvia Mariani, Samuel Heuts, Bas C T van Bussel, Michele Di Mauro, Dominik Wiedemann, Diyar Saeed, Matteo Pozzi, Antonio Loforte, Udo Boeken, Robertas Samalavicius, Karl Bounader, Xiaotong Hou, Jeroen J H Bunge, Hergen Buscher, Leonardo Salazar, Bart Meyns, Daniel Herr, Marco L Sacha Matteucci, Sandro Sponga, Graeme MacLaren, Claudio Russo, Francesco Formica, Pranya Sakiyalak, Antonio Fiore, Daniele Camboni, Giuseppe Maria Raffa, Rodrigo Diaz, I-Wen Wang, Jae-Seung Jung, Jan Belohlavek, Vin Pellegrino, Giacomo Bianchi, Matteo Pettinari, Alessandro Barbone, José P Garcia, Kiran Shekar, Glenn J R Whitman, Roberto Lorusso
Background Extracorporeal membrane oxygenation (ECMO) has been increasingly used for postcardiotomy cardiogenic shock, but without a concomitant reduction in observed in-hospital mortality. Long-term outcomes are unknown. This study describes patients' characteristics, in-hospital outcome, and 10-year survival after postcardiotomy ECMO. Variables associated with in-hospital and postdischarge mortality are investigated and reported. Methods and Results The retrospective international multicenter observational PELS-1 (Postcardiotomy Extracorporeal Life Support) study includes data on adults requiring ECMO for postcardiotomy cardiogenic shock between 2000 and 2020 from 34 centers...
July 18, 2023: Journal of the American Heart Association
#19
JOURNAL ARTICLE
Silvia Mariani, Anne-Kristin Schaefer, Bas C T van Bussel, Michele Di Mauro, Luca Conci, Philipp Szalkiewicz, Maria Elena De Piero, Samuel Heuts, Justine Ravaux, Iwan C C van der Horst, Diyar Saeed, Matteo Pozzi, Antonio Loforte, Udo Boeken, Robertas Samalavicius, Karl Bounader, Xiaotong Hou, Jeroen J H Bunge, Hergen Buscher, Leonardo Salazar, Bart Meyns, Daniel Herr, Sacha Matteucci, Sandro Sponga, Graeme MacLaren, Claudio Russo, Francesco Formica, Pranya Sakiyalak, Antonio Fiore, Daniele Camboni, Giuseppe Maria Raffa, Rodrigo Diaz, I-Wen Wang, Jae-Seung Jung, Jan Belohlavek, Vin Pellegrino, Giacomo Bianchi, Matteo Pettinari, Alessandro Barbone, José P Garcia, Glenn Whitman, Kiran Shekar, Dominik Wiedemann, Roberto Lorusso
BACKGROUND: Postcardiotomy venoarterial extracorporeal membrane oxygenation (VA ECMO) is characterized by discrepancies between weaning and survival-to-discharge rates. This study analyzes the differences between postcardiotomy VA ECMO patients who survived, died on ECMO, or died after ECMO weaning. Causes of death and variables associated with mortality at different time points are investigated. METHODS: The retrospective, multicenter, observational Postcardiotomy Extracorporeal Life Support Study (PELS) includes adults requiring postcardiotomy VA ECMO between 2000 and 2020...
November 2023: Annals of Thoracic Surgery
#20
JOURNAL ARTICLE
Natalie Kruit, Changle Song, David Tian, Emily Moylan, Mark Dennis
ObjectiveThe number of out-of-hospital cardiac arrest (OHCA) patients who may benefit from prehospital extracorporeal cardiopulmonary resuscitation (ECPR) is yet to be elucidated. Patient eligibility is determined both by case characteristics and physical proximity to an ECPR service. We applied accessibility principles to historical cardiac arrest data, to identify the number of patients who would have been eligible for prehospital ECPR in Sydney, Australia, and the potential survival benefit had prehospital ECPR been available...
June 26, 2023: Prehospital Emergency Care
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