Nader Shaikh, Natalia E Morone, John Lopez, Jennifer Chianese, Shilpa Sangvai, Frank D'Amico, Alejandro Hoberman, Ellen R Wald
CONTEXT: Urinary tract infection (UTI) is a frequently occurring pediatric illness that, if left untreated, can lead to permanent renal injury. Accordingly, accurate diagnosis of UTI is important. OBJECTIVE: To review the diagnostic accuracy of symptoms and signs for the diagnosis of UTI in infants and children. DATA SOURCES: A search of MEDLINE and EMBASE databases was conducted for articles published between 1966 and October 2007, as well as a manual review of bibliographies of all articles meeting inclusion criteria, 1 previously published systematic review, 3 clinical skills textbooks, and 2 experts in the field, yielding 6988 potentially relevant articles...
December 26, 2007: JAMA