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38 papers 25 to 100 followers Some dietary supplements to cope with Life
By Hugo Silva Pinto Sports medicine MD, neuromuscular pain and dysfunctions private practice
https://www.readbyqxmd.com/read/30176650/assortment-of-herbal-medicines-of-the-treatment-of-cardiovascular-diseases
#1
Ivanna V Sakhanda, Kostyantyn L Kosyachenko
OBJECTIVE: Introduction: Medicinal plants are an effective means of prevention of many cardiovascular diseases in high-risk groups. Also, they are often used as a means of adjuvant therapy. Centuries of experience in the use of medicinal plants in folk medicine is the result of their relatively high efficiency and their wide distribution in natural ecosystems, and sometimes close to human habitation. The aim of this work is to study the assortment of herbal medicinal products and to consider examples of the basic methods of treatment of cardiovascular diseases with medicinal plants...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/18500378/pharmacology-of-anabolic-steroids
#2
REVIEW
A T Kicman
Athletes and bodybuilders have recognized for several decades that the use of anabolic steroids can promote muscle growth and strength but it is only relatively recently that these agents are being revisited for clinical purposes. Anabolic steroids are being considered for the treatment of cachexia associated with chronic disease states, and to address loss of muscle mass in the elderly, but nevertheless their efficacy still needs to be demonstrated in terms of improved physical function and quality of life...
June 2008: British Journal of Pharmacology
https://www.readbyqxmd.com/read/23124786/effect-of-oral-anabolic-steroid-on-muscle-strength-and-muscle-growth-in-hemodialysis-patients
#3
RANDOMIZED CONTROLLED TRIAL
Ouppatham Supasyndh, Bancha Satirapoj, Pornanong Aramwit, Duangkamol Viroonudomphol, Amnart Chaiprasert, Vipa Thanachatwej, Supat Vanichakarn, Joel D Kopple
BACKGROUND AND OBJECTIVES: Sarcopenia is common in hemodialysis patients. This study examined whether the anabolic steroid oxymetholone improves muscle mass and handgrip strength in hemodialysis patients and possible mechanisms that might engender such changes. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Forty-three eligible hemodialysis patients were randomly assigned to ingest oxymetholone or placebo for 24 weeks. Body composition, handgrip strength, and quality of life were measured during the study...
February 2013: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/21575947/persistent-primary-hypogonadism-associated-with-anabolic-steroid-abuse
#4
Kusuma Boregowda, Lisa Joels, Jeffrey W Stephens, David E Price
OBJECTIVE: To report a case of primary gonadal failure due to the chronic abuse of anabolic steroids used for bodybuilding. DESIGN: Case report. SETTING: Department of Diabetes and Endocrinology, Morriston Hospital, Swansea, Wales, United Kingdom. PATIENT(S): A 40-year-old man. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Clinical symptoms, levels of serum T, FSH, and LH...
July 2011: Fertility and Sterility
https://www.readbyqxmd.com/read/21818626/the-anabolic-steroid-methandienone-targets-the-hypothalamic-pituitary-testicular-axis-and-myostatin-signaling-in-a-rat-training-model
#5
Stephanie Mosler, Carlos Pankratz, Alexis Seyfried, Marion Piechotta, Patrick Diel
There is increasing evidence that the biological activity of myostatin (MSTN), a negative regulator of muscle growth, is affected by training but also anabolic steroids. In this study, we analyzed the effects of the frequently abused anabolic steroid methandienone (Md) on the hypothalamic-pituitary-testicular axis and androgen-sensitive tissues in intact rats performing a treadmill training to simulate the situation of abusing athletes. The anabolic effects were correlated with the expression of members of the MSTN signaling cascade...
January 2012: Archives of Toxicology
https://www.readbyqxmd.com/read/29994823/physical-effects-of-anabolic-androgenic-steroids-in-healthy-exercising-adults-a-systematic-review-and-meta-analysis
#6
REVIEW
Mary A Andrews, Charles D Magee, Travis M Combest, Rhonda J Allard, Kevin M Douglas
Many athletes use anabolic-androgenic steroids (AAS) for physical enhancement but the magnitude of these gains and associated adverse effects has not been rigorously quantified. MEDLINE, EMBASE, Cochrane, SPORTDiscus, and PsycINFO were searched to identify randomized placebo-controlled trials of AAS in healthy exercising adults that reported one of the following outcomes: muscular strength, body composition, cardiovascular endurance, or power. Two authors appraised abstracts to identify studies for full-text retrieval; these were reviewed in duplicate to identify included studies...
July 2018: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29603319/role-of-melatonin-in-blood-pressure-regulation-an-adjunct-anti-hypertensive-agent
#7
REVIEW
Jacquie Baker, Kurt Kimpinski
Cardiovascular diseases account for approximately one-third of all deaths each year. Of this, hypertension accounts for approximately 9.4 million deaths. Melatonin, the primary circadian hormone, has been substantiated as an effective and safe adjunct anti-hypertensive agent. In support of this, melatonin receptors have been identified within the central and peripheral nervous system, as well as the cardiovascular system, including various vascular tissues. Therefore, it is not surprising that recent research has emerged highlighting a key role of melatonin in autonomic regulation of blood pressure...
August 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29019089/exercise-and-the-cortisol-awakening-response-a-systematic-review
#8
REVIEW
Travis Anderson, Laurie Wideman
BACKGROUND: The cortisol awakening response (CAR) has been used as a biomarker of stress response in a multitude of psychological investigations. While a myriad of biochemical responses have been proposed to monitor responses to exercise training, the use of CAR within the exercise and sports sciences is currently limited and is a potentially underutilized variable. Therefore, the purpose of this review was to collate studies that incorporate both exercise and CAR, in an effort to better understand (a) whether CAR is a useful marker for monitoring exercise stress and (b) how CAR may be most appropriately used in future research...
October 10, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/29077022/effects-of-creatine-supplementation-on-muscle-strength-and-optimal-individual-post-activation-potentiation-time-of-the-upper-body-in-canoeists
#9
RANDOMIZED CONTROLLED TRIAL
Chia-Chi Wang, Shu-Cheng Lin, Shu-Ching Hsu, Ming-Ta Yang, Kuei-Hui Chan
Creatine supplementation reduces the impact of muscle fatigue on post-activation potentiation (PAP) of the lower body, but its effects on the upper body remain unknown. This study examined the effects of creatine supplementation on muscle strength, explosive power, and optimal individual PAP time of the upper body during a set of complex training bouts in canoeists. Seventeen male high school canoeists performed a bench row for one repetition at maximum strength and conducted complex training bouts to determine the optimal individual timing of PAP and distance of overhead medicine ball throw before and after the supplementation...
October 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28978542/consumption-of-whole-eggs-promotes-greater-stimulation-of-postexercise-muscle-protein-synthesis-than-consumption-of-isonitrogenous-amounts-of-egg-whites-in-young-men
#10
RANDOMIZED CONTROLLED TRIAL
Stephan van Vliet, Evan L Shy, Sidney Abou Sawan, Joseph W Beals, Daniel Wd West, Sarah K Skinner, Alexander V Ulanov, Zhong Li, Scott A Paluska, Carl M Parsons, Daniel R Moore, Nicholas A Burd
Background: Protein in the diet is commonly ingested from whole foods that contain various macro- and micronutrients. However, the effect of consuming protein within its natural whole-food matrix on postprandial protein metabolism remains understudied in humans. Objective: We aimed to compare the whole-body and muscle protein metabolic responses after the consumption of whole eggs with egg whites during exercise recovery in young men. Design: In crossover trials, 10 resistance-trained men [aged 21 ± 1 y; 88 ± 3 kg; body fat: 16% ± 1% (means ± SEMs)] received primed continuous l-[ ring -2 H5 ]phenylalanine and l-[1-13 C]leucine infusions and performed a single bout of resistance exercise...
December 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28776086/the-mechanisms-of-action-of-metformin
#11
REVIEW
Graham Rena, D Grahame Hardie, Ewan R Pearson
Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and diabetes-related complications. The mechanisms underlying these benefits are complex and still not fully understood. Physiologically, metformin has been shown to reduce hepatic glucose production, yet not all of its effects can be explained by this mechanism and there is increasing evidence of a key role for the gut. At the molecular level the findings vary depending on the doses of metformin used and duration of treatment, with clear differences between acute and chronic administration...
September 2017: Diabetologia
https://www.readbyqxmd.com/read/28615996/international-society-of-sports-nutrition-position-stand-safety-and-efficacy-of-creatine-supplementation-in-exercise-sport-and-medicine
#12
REVIEW
Richard B Kreider, Douglas S Kalman, Jose Antonio, Tim N Ziegenfuss, Robert Wildman, Rick Collins, Darren G Candow, Susan M Kleiner, Anthony L Almada, Hector L Lopez
Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have consistently shown that creatine supplementation increases intramuscular creatine concentrations which may help explain the observed improvements in high intensity exercise performance leading to greater training adaptations. In addition to athletic and exercise improvement, research has shown that creatine supplementation may enhance post-exercise recovery, injury prevention, thermoregulation, rehabilitation, and concussion and/or spinal cord neuroprotection...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28489931/cortical-involvement-in-celiac-disease-before-and-after-long-term-gluten-free-diet-a-transcranial-magnetic-stimulation-study
#13
Manuela Pennisi, Giuseppe Lanza, Mariagiovanna Cantone, Riccardo Ricceri, Raffaele Ferri, Carmela Cinzia D'Agate, Giovanni Pennisi, Vincenzo Di Lazzaro, Rita Bella
OBJECTIVE: Transcranial Magnetic Stimulation in de novo patients with Celiac Disease previously revealed an imbalance in the excitability of cortical facilitatory and inhibitory circuits. After a median period of 16 months of gluten-free diet, a global increase of cortical excitability was reported, suggesting a glutamate-mediated compensation for disease progression. We have now evaluated cross-sectionally the changes of cortical excitability to TMS after a much longer gluten-free diet...
2017: PloS One
https://www.readbyqxmd.com/read/28018095/gastrointestinal-neuromuscular-apparatus-an-underestimated-target-of-gut-microbiota
#14
REVIEW
Michele Pier Luca Guarino, Michele Cicala, Lorenza Putignani, Carola Severi
Over the last few years, the importance of the resident intestinal microbiota in the pathogenesis of several gastro-intestinal diseases has been largely investigated. Growing evidence suggest that microbiota can influence gastro-intestinal motility. The current working hypothesis is that dysbiosis-driven mucosal alterations induce the production of several inflammatory/immune mediators which affect gut neuro-muscular functions. Besides these indirect mucosal-mediated effects, the present review highlights that recent evidence suggests that microbiota can directly affect enteric nerves and smooth muscle cells functions through its metabolic products or bacterial molecular components translocated from the intestinal lumen...
December 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27649242/a-systematic-review-of-athletes-and-coaches-nutrition-knowledge-and-reflections-on-the-quality-of-current-nutrition-knowledge-measures
#15
REVIEW
Gina L Trakman, Adrienne Forsyth, Brooke L Devlin, Regina Belski
CONTEXT: Nutrition knowledge can influence dietary choices and impact on athletic performance. Valid and reliable measures are needed to assess the nutrition knowledge of athletes and coaches. OBJECTIVES: (1) To systematically review the published literature on nutrition knowledge of adult athletes and coaches and (2) to assess the quality of measures used to assess nutrition knowledge. DATA SOURCES: MEDLINE, CINAHL, SPORTDiscuss, Web of Science, and SCOPUS...
September 16, 2016: Nutrients
https://www.readbyqxmd.com/read/27560446/mechanisms-by-which-cocoa-flavanols-improve-metabolic-syndrome-and-related-disorders
#16
REVIEW
Karen M Strat, Thomas J Rowley, Andrew T Smithson, Jeffery S Tessem, Matthew W Hulver, Dongmin Liu, Brenda M Davy, Kevin P Davy, Andrew P Neilson
Dietary administration of cocoa flavanols may be an effective complementary strategy for alleviation or prevention of metabolic syndrome, particularly glucose intolerance. The complex flavanol composition of cocoa provides the ability to interact with a variety of molecules, thus allowing numerous opportunities to ameliorate metabolic diseases. These interactions likely occur primarily in the gastrointestinal tract, where native cocoa flavanol concentration is high. Flavanols may antagonize digestive enzymes and glucose transporters, causing a reduction in glucose excursion, which helps patients with metabolic disorders maintain glucose homeostasis...
September 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/24681572/nitrate-supplementation-enhances-the-contractile-properties-of-human-skeletal-muscle
#17
RANDOMIZED CONTROLLED TRIAL
Georg Haider, Jonathan P Folland
PURPOSE: Dietary nitrate supplementation positively affects cardiovascular function at rest and energy metabolism during exercise in humans and has recently also been reported to markedly enhance the in vitro contractile properties of mouse fast-twitch muscle. The aim of this study was to investigate the effects of short-term nitrate supplementation on the in vivo contractile properties of the skeletal muscle and voluntary muscle function of humans. METHODS: In a double-blind, randomized, crossover design, 19 healthy untrained men (21 ± 3 yr) ingested a nitrate-rich concentrated beetroot juice (NIT; nitrate dosage, approximately 9...
December 2014: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/26497149/can-doping-be-a-good-thing-using-psychoactive-drugs-to-facilitate-physical-activity-behaviour
#18
REVIEW
Samuele Marcora
No abstract text is available yet for this article.
January 2016: Sports Medicine
https://www.readbyqxmd.com/read/27432852/the-female-athlete-triad
#19
Amanda K Weiss Kelly, Suzanne Hecht
The number of girls participating in sports has increased significantly since the introduction of Title XI in 1972. As a result, more girls have been able to experience the social, educational, and health-related benefits of sports participation. However, there are risks associated with sports participation, including the female athlete triad. The triad was originally recognized as the interrelationship of amenorrhea, osteoporosis, and disordered eating, but our understanding has evolved to recognize that each of the components of the triad exists on a spectrum from optimal health to disease...
August 2016: Pediatrics
https://www.readbyqxmd.com/read/27466609/serum-zinc-is-a-major-predictor-of-anemia-and-mediates-the-effect-of-selenium-on-hemoglobin-in-school-aged-children-in-a-nationally-representative-survey-in-new-zealand
#20
Lisa A Houghton, Winsome R Parnell, Christine D Thomson, Timothy J Green, Rosalind S Gibson
BACKGROUND: Zinc, selenium, and vitamin D status of New Zealand (NZ) school-aged children was examined in a national survey in 2002. To our knowledge, however, the role of these micronutrients as predictors of hemoglobin has not been explored despite plausible mechanisms for such relations. OBJECTIVE: We examined the relations of iron, zinc, selenium, and vitamin D status with hemoglobin and anemia in children of New Zealand European and other (NZEO) ethnicity enrolled in the 2002 Children's Nutrition Survey and explored whether zinc mediated the relation between selenium and hemoglobin...
September 2016: Journal of Nutrition
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