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JOURNAL ARTICLE
Yi Luo, Yongqin Zhou, Wei Xiao, Zhihui Liang, Jiapei Dai, Xiufang Weng, Xiongwen Wu
Ischemic stroke causes brain injury with activation of an inflammatory response that can contribute to clinical impairment. As a novel cytokine of the interleukin-1 (IL-1) family, IL-33 has been suggested to be involved in regulating pathophysiology and inflammatory responses in the central nervous system (CNS). However, the role and underlying mechanisms of IL-33 in ischemic stroke remain poorly understood. Here, adult male C57BL/6 mice were subjected to middle cerebral artery occlusion (MCAO) for stroke induction...
February 9, 2015: Brain Research
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