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Stroke therapies

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Yi Luo, Yongqin Zhou, Wei Xiao, Zhihui Liang, Jiapei Dai, Xiufang Weng, Xiongwen Wu
Ischemic stroke causes brain injury with activation of an inflammatory response that can contribute to clinical impairment. As a novel cytokine of the interleukin-1 (IL-1) family, IL-33 has been suggested to be involved in regulating pathophysiology and inflammatory responses in the central nervous system (CNS). However, the role and underlying mechanisms of IL-33 in ischemic stroke remain poorly understood. Here, adult male C57BL/6 mice were subjected to middle cerebral artery occlusion (MCAO) for stroke induction...
February 9, 2015: Brain Research
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