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Neonatal Ventilation

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9 papers 0 to 25 followers
By Zahid Anwar Consultant Neonatologist
https://www.readbyqxmd.com/read/25669725/real-time-pulmonary-graphics
#1
REVIEW
Mark C Mammel, Steven M Donn
Real-time pulmonary graphics now enable clinicians to view lung mechanics and patient-ventilator interactions on a breath-to-breath basis. Displays of pressure, volume, and flow waveforms, pressure-volume and flow-volume loops, and trend screens enable clinicians to customize ventilator settings based on the underlying pathophysiology and responses of the individual patient. This article reviews the basic concepts of pulmonary graphics and demonstrates how they contribute to our understanding of respiratory physiology and the management of neonatal respiratory failure...
June 2015: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/24846520/changes-in-ventilator-strategies-and-outcomes-in-preterm-infants
#2
MULTICENTER STUDY
Valentina Vendettuoli, Roberto Bellù, Rinaldo Zanini, Fabio Mosca, Luigi Gagliardi
BACKGROUND: Although life-saving, intubation and mechanical ventilation can lead to complications including bronchopulmonary dysplasia (BPD). In order to reduce the incidence of BPD, non-invasive ventilation (NIV) is increasingly used. OBJECTIVE: The aim of our study was to describe changes in ventilator strategies and outcomes between 2006 and 2010 in the Italian Neonatal Network (INN). DESIGN: Multicentre cohort study. SETTINGS: 31 tertiary level neonatal units participating in INN in 2006 and 2010...
July 2014: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/24725582/respiratory-outcomes-of-the-surfactant-positive-pressure-and-oximetry-randomized-trial-support
#3
RANDOMIZED CONTROLLED TRIAL
Timothy P Stevens, Neil N Finer, Waldemar A Carlo, Peter G Szilagyi, Dale L Phelps, Michele C Walsh, Marie G Gantz, Abbot R Laptook, Bradley A Yoder, Roger G Faix, Jamie E Newman, Abhik Das, Barbara T Do, Kurt Schibler, Wade Rich, Nancy S Newman, Richard A Ehrenkranz, Myriam Peralta-Carcelen, Betty R Vohr, Deanne E Wilson-Costello, Kimberly Yolton, Roy J Heyne, Patricia W Evans, Yvonne E Vaucher, Ira Adams-Chapman, Elisabeth C McGowan, Anna Bodnar, Athina Pappas, Susan R Hintz, Michael J Acarregui, Janell Fuller, Ricki F Goldstein, Charles R Bauer, T Michael O'Shea, Gary J Myers, Rosemary D Higgins
OBJECTIVE: To explore the early childhood pulmonary outcomes of infants who participated in the National Institute of Child Health and Human Development's Surfactant Positive Airway Pressure and Pulse Oximetry Randomized Trial (SUPPORT), using a factorial design that randomized extremely preterm infants to lower vs higher oxygen saturation targets and delivery room continuous positive airway pressure (CPAP) vs intubation/surfactant. STUDY DESIGN: The Breathing Outcomes Study, a prospective secondary study to the Surfactant Positive Airway Pressure and Pulse Oximetry Randomized Trial, assessed respiratory morbidity at 6-month intervals from hospital discharge to 18-22 months corrected age (CA)...
August 2014: Journal of Pediatrics
https://www.readbyqxmd.com/read/25089718/minimally-invasive-surfactant-administration-in-preterm-infants-a-meta-narrative-review
#4
REVIEW
Kiran More, Pankaj Sakhuja, Prakesh S Shah
IMPORTANCE: Surfactant administration by minimally invasive methods that allow for spontaneous breathing might be safer and more effective than administration with endotracheal intubation and mechanical ventilation; however, the efficacy and safety of minimally invasive methods have not been reviewed. OBJECTIVE: To conduct a meta-narrative review of the efficacy and safety of minimally invasive surfactant administration using a thin catheter, aerosolization, a laryngeal mask airway, and pharyngeal administration in preterm infants with or at risk for respiratory distress syndrome...
October 2014: JAMA Pediatrics
https://www.readbyqxmd.com/read/25550472/sustained-inflation-versus-positive-pressure-ventilation-at-birth-a-systematic-review-and-meta-analysis
#5
REVIEW
Georg M Schmölzer, Manoj Kumar, Khalid Aziz, Gerhard Pichler, Megan O'Reilly, Gianluca Lista, Po-Yin Cheung
CONTEXT: Sustained inflation (SI) has been advocated as an alternative to intermittent positive pressure ventilation (IPPV) during the resuscitation of neonates at birth, to facilitate the early development of an effective functional residual capacity, reduce atelectotrauma and improve oxygenation after the birth of preterm infants. OBJECTIVE: The primary aim was to review the available literature on the use of SI compared with IPPV at birth in preterm infants for major neonatal outcomes, including bronchopulmonary dysplasia (BPD) and death...
July 2015: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/24942746/effects-of-synchronisation-during-sipap-generated-nasal-intermittent-positive-pressure-ventilation-nippv-in-preterm-infants
#6
L S Owen, C J Morley, P G Davis
OBJECTIVE: The SiPAP flow driver (Care Fusion, Dublin, Ohio, USA) offers synchronised nasal intermittent positive pressure ventilation (sNIPPV) using an abdominal capsule. This study aims to describe the accuracy and effects of synchronised NIPPV using SiPAP in preterm infants. DESIGN: Ten infants, born <28 weeks' gestation, receiving synchronised SiPAP-generated NIPPV, in 'biphasic trigger' mode, were observed. Abdominal capsule signals, delivered pressures, respiratory pattern and oxygen saturations were recorded...
January 2015: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/25667244/noninvasive-ventilation-strategies-for-early-treatment-of-rds-in-preterm-infants-an-rct
#7
RANDOMIZED CONTROLLED TRIAL
Vincenzo Salvo, Gianluca Lista, Enrica Lupo, Alberto Ricotti, Luc J I Zimmermann, Antonio W D Gavilanes, Ignazio Barberi, Micaela Colivicchi, Francesca Temporini, Diego Gazzolo
BACKGROUND AND OBJECTIVES: There is evidence that new methods of noninvasive ventilation (NIV) support have significantly changed respiratory distress syndrome (RDS) management in preterm infants. Further perspectives for neonatologists involve the assessment of different NIV strategies in terms of availability, effectiveness, and failure. This study evaluates the efficacy of 2 different NIV strategies for RDS treatment in very low birth weight (VLBW) infants: nasal synchronized intermittent positive pressure ventilation (NSIPPV), which is a modality of conventional ventilation with intermittent peak inspiratory pressure, and bilevel continuous positive airway pressure (BiPAP), not synchronized, with 2 alternate levels of continuous positive airway pressure...
March 2015: Pediatrics
https://www.readbyqxmd.com/read/24812104/ceasing-cpap-at-standard-criteria-cicada-impact-on-weight-gain-time-to-full-feeds-and-caffeine-use
#8
RANDOMIZED CONTROLLED TRIAL
Margaret Broom, Lei Ying, Audrey Wright, Alice Stewart, Mohamed E Abdel-Latif, Bruce Shadbolt, David A Todd
INTRODUCTION: In our previous randomised controlled trial (RCT), we have shown in preterm babies (PBs) <30 weeks gestation that CeasIng Cpap At standarD criteriA (CICADA (method 1)) compared with cycling off continuous positive airway pressure (CPAP) gradually (method 2) or cycling off CPAP gradually with low flow air/oxygen during periods off CPAP (method 3) reduces CPAP cessation time in PBs <30 weeks gestation. METHOD: This retrospective study reviewed weight gain, time to reach full feeds and time to cease caffeine in PBs previously enrolled in the RCT...
September 2014: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/24876196/change-in-practice-after-the-surfactant-positive-pressure-and-oxygenation-randomised-trial
#9
MULTICENTER STUDY
Jaclyn M LeVan, Luc P Brion, Lisa A Wrage, Marie G Gantz, Myra H Wyckoff, Pablo J Sánchez, Roy Heyne, Mambarambath Jaleel, Neil N Finer, Waldemar A Carlo, Abhik Das, Barbara J Stoll, Rosemary D Higgins
OBJECTIVE: To test the hypothesis that the proportion of endotracheal intubation (ETI) in the delivery room (DR) decreased in Neonatal Research Network (NRN) centres after the National Institute of Child Health and Human Development NRN Surfactant, Positive Pressure, and Oxygenation Randomised Trial (SUPPORT). DESIGN: Retrospective cohort study using the prospective NRN generic database. SETTING: Eleven centres that participated in the SUPPORT trial and remained part of the NRN...
September 2014: Archives of Disease in Childhood. Fetal and Neonatal Edition
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