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Lithium

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5 papers 0 to 25 followers
By Abraham Nunes Psychiatry resident interested in computational neuroscience, forensic psychiatry, and neuropsychiatry.
https://www.readbyqxmd.com/read/26183461/the-suicide-prevention-effect-of-lithium-more-than-20%C3%A2-years-of-evidence-a-narrative-review
#1
U Lewitzka, E Severus, R Bauer, P Ritter, B Müller-Oerlinghausen, M Bauer
The management and treatment of patients with suicidal behavior is one of the most challenging tasks for health-care professionals. Patients with affective disorders are at high risk for suicidal behavior, therefore, should be a target for prevention. Numerous international studies of lithium use have documented anti-suicidal effects since the 1970s. Despite the unambiguous evidence of lithium's anti-suicidal effects and recommendations in national and international guidelines for its use in acute and maintenance therapy of affective disorders, the use of lithium is still underrepresented...
December 2015: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/26003379/long-term-effects-of-lithium-on-renal-thyroid-and-parathyroid-function-a-retrospective-analysis-of-laboratory-data
#2
Brian Shine, Rebecca F McKnight, Laurence Leaver, John R Geddes
BACKGROUND: Lithium is a widely used and highly effective treatment for mood disorders, but causes poorly characterised adverse effects in kidney and endocrine systems. We aimed to analyse laboratory information system data to determine the incidence of renal, thyroid, and parathyroid dysfunction associated with lithium use. METHODS: In a retrospective analysis of laboratory data from Oxford University Hospitals National Health Service Trust (Oxfordshire, UK), we investigated the incidence of renal, thyroid, and parathyroid dysfunction in patients (aged ≥18 years) who had at least two creatinine, thyrotropin, calcium, glycated haemoglobin, or lithium measurements between Oct 1, 1982, and March 31, 2014, compared with controls who had not had lithium measurements taken...
August 1, 2015: Lancet
https://www.readbyqxmd.com/read/25700119/low-risk-of-male-suicide-and-lithium-in-drinking-water
#3
Nobuyoshi Ishii, Takeshi Terao, Yasuo Araki, Kentaro Kohno, Yoshinori Mizokami, Ippei Shiotsuki, Koji Hatano, Mayu Makino, Kensuke Kodama, Noboru Iwata
OBJECTIVE: Recently, several epidemiologic studies reported that lithium in drinking water may be associated with lower rates of suicide mortality at the population level, but other studies failed to confirm the association. The objective of the present study is to determine whether lithium in drinking water is associated with lower suicide rate after adjustment of potential confounding factors. METHOD: From 2010 to 2013, 274 mean lithium levels of 434 lithium samples in drinking water were examined in relation to suicide standardized mortality ratios (SMRs) in 274 municipalities of Kyushu Island in Japan...
March 2015: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/25553494/hypercalcemia-and-primary-hyperparathyroidism-during-lithium-therapy
#4
Howard I Shapiro, Karina A Davis
No abstract text is available yet for this article.
January 2015: American Journal of Psychiatry
https://www.readbyqxmd.com/read/16061763/suicide-risk-in-patients-treated-with-lithium
#5
COMPARATIVE STUDY
Lars Vedel Kessing, Lars Søndergård, Kajsa Kvist, Per Kragh Andersen
CONTEXT: Prior observational studies suggest that treatment with lithium may be associated with reduced risk of suicide in bipolar disorder. However, these studies are biased toward patients with the most severe disorders, and the relation to sex and age has seldom been investigated. OBJECTIVE: To investigate whether treatment with lithium reduces the risk of suicide in a nationwide study. DESIGN: An observational cohort study with linkage of registers of all prescribed lithium and recorded suicides in Denmark during a period from January 1, 1995, to December 31, 1999...
August 2005: Archives of General Psychiatry
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