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17 papers 25 to 100 followers
https://www.readbyqxmd.com/read/26926851/computer-assisted-diagnostic-checklist-in-clinical-neurology
#1
Pasquale F Finelli, Andrew L McCabe
Considering computers are more efficient at processing large amounts of information than the human brain, speaks to the need to explore more intelligent computer-assisted diagnostic approaches. Two diagnostic checklist programs, one for single key term entry (NeurologyINDEX), and another, with more advanced algorithms to process multiple key terms and perform additional functions (NeurologicDx) are discussed. Both programs are internet based, access the same database, and are designed to generate diagnostic checklists and disease profiles accessible with hand-held or other computer device...
March 2016: Neurologist
https://www.readbyqxmd.com/read/26906964/a-clinical-approach-to-diagnosis-of-autoimmune-encephalitis
#2
REVIEW
Francesc Graus, Maarten J Titulaer, Ramani Balu, Susanne Benseler, Christian G Bien, Tania Cellucci, Irene Cortese, Russell C Dale, Jeffrey M Gelfand, Michael Geschwind, Carol A Glaser, Jerome Honnorat, Romana Höftberger, Takahiro Iizuka, Sarosh R Irani, Eric Lancaster, Frank Leypoldt, Harald Prüss, Alexander Rae-Grant, Markus Reindl, Myrna R Rosenfeld, Kevin Rostásy, Albert Saiz, Arun Venkatesan, Angela Vincent, Klaus-Peter Wandinger, Patrick Waters, Josep Dalmau
Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a complex differential diagnosis. Advances in autoimmune encephalitis research in the past 10 years have led to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to these disorders. However, existing criteria for autoimmune encephalitis are too reliant on antibody testing and response to immunotherapy, which might delay the diagnosis. We reviewed the literature and gathered the experience of a team of experts with the aims of developing a practical, syndrome-based diagnostic approach to autoimmune encephalitis and providing guidelines to navigate through the differential diagnosis...
April 2016: Lancet Neurology
https://www.readbyqxmd.com/read/26370690/acute-heart-failure-and-cardiogenic-shock-a-multidisciplinary-practical-guidance
#3
REVIEW
A Mebazaa, H Tolppanen, C Mueller, J Lassus, S DiSomma, G Baksyte, M Cecconi, D J Choi, A Cohen Solal, M Christ, J Masip, M Arrigo, S Nouira, D Ojji, F Peacock, M Richards, N Sato, K Sliwa, J Spinar, H Thiele, M B Yilmaz, J Januzzi
PURPOSE: Acute heart failure (AHF) causes high burden of mortality, morbidity, and repeated hospitalizations worldwide. This guidance paper describes the tailored treatment approaches of different clinical scenarios of AHF and CS, focusing on the needs of professionals working in intensive care settings. RESULTS: Tissue congestion and hypoperfusion are the two leading mechanisms of end-organ injury and dysfunction, which are associated with worse outcome in AHF...
February 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/26376969/myasthenia-gravis-subgroup-classification-and-therapeutic-strategies
#4
REVIEW
Nils Erik Gilhus, Jan J Verschuuren
Myasthenia gravis is an autoimmune disease that is characterised by muscle weakness and fatigue, is B-cell mediated, and is associated with antibodies directed against the acetylcholine receptor, muscle-specific kinase (MUSK), lipoprotein-related protein 4 (LRP4), or agrin in the postsynaptic membrane at the neuromuscular junction. Patients with myasthenia gravis should be classified into subgroups to help with therapeutic decisions and prognosis. Subgroups based on serum antibodies and clinical features include early-onset, late-onset, thymoma, MUSK, LRP4, antibody-negative, and ocular forms of myasthenia gravis...
October 2015: Lancet Neurology
https://www.readbyqxmd.com/read/25908090/status-epilepticus-in-adults
#5
REVIEW
John P Betjemann, Daniel H Lowenstein
Status epilepticus is a common neurological emergency with considerable associated health-care costs, morbidity, and mortality. The definition of status epilepticus as a prolonged seizure or a series of seizures with incomplete return to baseline is under reconsideration in an effort to establish a more practical definition to guide management. Clinical research has focused on early seizure termination in the prehospital setting. The approach of early escalation to anaesthetic agents for refractory generalised convulsive status epilepticus, rather than additional trials of second-line anti-epileptic drugs, to avoid neuronal injury and pharmaco-resistance associated with prolonged seizures is gaining momentum...
June 2015: Lancet Neurology
https://www.readbyqxmd.com/read/26176382/clinical-practice-heparin-induced-thrombocytopenia
#6
REVIEW
Andreas Greinacher
New England Journal of Medicine, Volume 373, Issue 3, Page 252-261, July 2015.
July 16, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/25875259/clostridium-difficile-infection
#7
REVIEW
Daniel A Leffler, J Thomas Lamont
New England Journal of Medicine, Volume 372, Issue 16, Page 1539-1548, April 2015.
April 16, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/26045965/mechanical-ventilation-of-acute-respiratory-distress-syndrome
#8
REVIEW
Ryoichi Ochiai
Acute respiratory distress syndrome (ARDS) has been intensively and continuously studied in various settings, but its mortality is still as high as 30-40 %. For the last 20 years, lung protective strategy has become a standard care for ARDS, but we still do not know the best way to ventilate patients with ARDS. Tidal volume itself does not seem to have an important role to develop ventilator-induced lung injury (VILI), but the driving pressure, which is inspiratory plateau pressure-PEEP, is the most important to predict and affect the outcome of ARDS, though there is no safe limit for the driving pressure...
2015: Journal of Intensive Care
https://www.readbyqxmd.com/read/25752308/acute-kidney-injury-in-the-critically-ill-patient-a-current-review-of-the-literature
#9
Andrea M Pakula, Ruby A Skinner
PURPOSE: A comprehensive review of the literature to provide a focused and thorough update on the issue of acute kidney injury (AKI) in the surgical patient. METHODS: A PubMed and Medline search was performed and keywords included AKI, renal failure, critically ill, and renal replacement therapy (RRT). PRINCIPAL FINDINGS: A common clinical problem encountered in critically ill patients is AKI. The recent consensus definitions for the diagnosis and classification of AKI (ie, Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease/Acute Kidney Injury Network) have enabled us to standardize the severity of AKI and facilitate strategies for prevention...
June 2016: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/25583188/evaluation-of-the-utility-of-the-vigileo-flotrac-%C3%A2-lidco-%C3%A2-uscom-and-cardioq-%C3%A2-to-detect-hypovolaemia-in-conscious-volunteers-a-proof-of-concept-study
#10
E O'Loughlin, M Ward, A Crossley, R Hughes, A P Bremner, T Corcoran
It is important to detect and treat hypovolaemia; however, detection is particularly challenging in the conscious, spontaneously breathing patient. Eight healthy male volunteers were monitored using four minimally invasive monitors: Vigileo FloTrac(™) ; LiDCOrapid(™) ; USCOM 1A; and CardioQ(™) oesophageal Doppler. Monitor output and clinical signs were recorded during incremental venesection of 2.5% estimated blood volume aliquots to a total of 20% blood volume removed. A statistically significant difference from baseline stroke volume was detected after 2...
February 2015: Anaesthesia
https://www.readbyqxmd.com/read/25372090/integration-of-acid-base-and-electrolyte-disorders
#11
REVIEW
Julian L Seifter
No abstract text is available yet for this article.
November 6, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/25295509/videos-in-clinical-medicine-ultrasound-guided-insertion-of-a-radial-arterial-catheter
#12
Jonathan Ailon, Ophyr Mourad, Vince Chien, Tomas Saun, Shelly P Dev
New England Journal of Medicine, Volume 371, Issue 15, October 2014.
October 9, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/25213433/acid-base-disturbances-in-intensive-care-patients-etiology-pathophysiology-and-treatment
#13
REVIEW
Mohammed Al-Jaghbeer, John A Kellum
Acid-base disturbances are very common in critically ill and injured patients as well as contribute significantly to morbidity and mortality. An understanding of the pathophysiology of these disorders is vital to their proper management. This review will discuss the etiology, pathophysiology and treatment of acid-base disturbances in intensive care patients--with particular attention to evidence from recent studies examining the effects of fluid resuscitation on acid-base and its consequences.
July 2015: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/25047428/fluid-resuscitation-in-sepsis-a-systematic-review-and-network-meta-analysis
#14
REVIEW
Bram Rochwerg, Waleed Alhazzani, Anees Sindi, Diane Heels-Ansdell, Lehana Thabane, Alison Fox-Robichaud, Lawrence Mbuagbaw, Wojciech Szczeklik, Fayez Alshamsi, Sultan Altayyar, Wang-Chun Ip, Guowei Li, Michael Wang, Anna Wludarczyk, Qi Zhou, Gordon H Guyatt, Deborah J Cook, Roman Jaeschke, Djillali Annane
BACKGROUND: Fluid resuscitation is the cornerstone of sepsis treatment. However, whether balanced or unbalanced crystalloids or natural or synthetic colloids confer a survival advantage is unclear. PURPOSE: To examine the effect of different resuscitative fluids on mortality in patients with sepsis. DATA SOURCES: MEDLINE, EMBASE, ACP Journal Club, CINAHL, HealthSTAR, the Allied and Complementary Medicine Database, and the Cochrane Central Register of Controlled Trials through March 2014...
September 2, 2014: Annals of Internal Medicine
https://www.readbyqxmd.com/read/24758618/icu-acquired-weakness-and-recovery-from-critical-illness
#15
REVIEW
John P Kress, Jesse B Hall
New England Journal of Medicine, Volume 370, Issue 17, Page 1626-1635, April 2014.
April 24, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/24571757/bleeding-and-coagulopathies-in-critical-care
#16
REVIEW
Beverley J Hunt
No abstract text is available yet for this article.
February 27, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/16646987/efficacy-and-safety-of-non-invasive-ventilation-in-the-treatment-of-acute-cardiogenic-pulmonary-edema-a-systematic-review-and-meta-analysis
#17
REVIEW
João C Winck, Luís F Azevedo, Altamiro Costa-Pereira, Massimo Antonelli, Jeremy C Wyatt
INTRODUCTION: Continuous positive airway pressure ventilation (CPAP) and non-invasive positive pressure ventilation (NPPV) are accepted treatments in acute cardiogenic pulmonary edema (ACPE). However, it remains unclear whether NPPV is better than CPAP in reducing the need for endotracheal intubation (NETI) rates, mortality and other adverse events. Our aim was to review the evidence about the efficacy and safety of these two methods in ACPE management. METHODS: We conducted a systematic review and meta-analysis of randomized controlled trials on the effect of CPAP and/or NIPV in the treatment of ACPE, considering the outcomes NETI, mortality and incidence of acute myocardial infarction (AMI)...
2006: Critical Care: the Official Journal of the Critical Care Forum
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