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Identification of a Common Neurobiological Substrate for Mental Illness

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https://www.readbyqxmd.com/read/25651064/identification-of-a-common-neurobiological-substrate-for-mental-illness
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Madeleine Goodkind, Simon B Eickhoff, Desmond J Oathes, Ying Jiang, Andrew Chang, Laura B Jones-Hagata, Brissa N Ortega, Yevgeniya V Zaiko, Erika L Roach, Mayuresh S Korgaonkar, Stuart M Grieve, Isaac Galatzer-Levy, Peter T Fox, Amit Etkin
IMPORTANCE: Psychiatric diagnoses are currently distinguished based on sets of specific symptoms. However, genetic and clinical analyses find similarities across a wide variety of diagnoses, suggesting that a common neurobiological substrate may exist across mental illness. OBJECTIVE: To conduct a meta-analysis of structural neuroimaging studies across multiple psychiatric diagnoses, followed by parallel analyses of 3 large-scale healthy participant data sets to help interpret structural findings in the meta-analysis...
April 2015: JAMA Psychiatry
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