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Percutaneous Peripheral nerve stimulation and neurologic disorders

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264 papers 25 to 100 followers Use of Percutaneous Peripheral nerve and motor point stimulation to modulate the neuroplastic changes ocurred in the peripheral and central nervous Systems in cronic and acute pain patients
By Hugo Silva Pinto Sports medicine MD, neuromuscular pain and dysfunctions private practice
https://www.readbyqxmd.com/read/29666777/injury-of-the-radial-nerve-in-the-arm-a-review
#1
REVIEW
Taroob J Latef, Muhammad Bilal, Marc Vetter, Joe Iwanaga, Rod J Oskouian, R Shane Tubbs
Compression of the radial nerve is most commonly described at the supinator muscle (i.e., arcade of Frohse). However, radial nerve compression can occur in the arm. Therefore, the purpose of this article is to review both etiologies of radial nerve entrapment and the sites at which this can occur in the arm. The clinical presentation of radial nerve entrapment in the arm and how it differs from that of entrapment at other sites is reviewed and the conditions potentially predisposing to nerve entrapment are described...
February 16, 2018: Curēus
https://www.readbyqxmd.com/read/29608974/pain-neuroimaging-in-humans-a-primer-for-beginners-and-non-imagers
#2
Massieh Moayedi, Tim V Salomons, Lauren Y Atlas
The field of human pain neuroimaging has exploded in the last two decades. During this time, the broader neuroimaging community has continued to investigate and refine methods. Another key to progress is exchange with clinicians and pain scientists working with other model systems and approaches. These collaborative efforts require that non-imagers be able to evaluate and assess the evidence provided in these papers. Likewise, new trainees must design rigorous and reliable pain imaging experiments. Here, we provide a guideline for designing, reading, evaluating, analyzing, and reporting results of a pain neuroimaging experiment, with a focus on functional and structural MRI...
March 30, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29600889/transcranial-direct-current-stimulation-in-the-modulation-of-neuropathic-pain-a-systematic-review
#3
Mírian Celly Medeiros Miranda David, Alexa Alves de Moraes, Maíra Lopes da Costa, Carlúcia Ithamar Fernandes Franco
Objective To investigate the neuromodulating effect of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Pain (NP). Method A systematic review of articles published in the past five years in MEDLINE, LILACS, Cochrane, Scopus, ScienceDirect, and PEDro. The search was carried out from February to May 2017 using the keywords: neuropathic pain, neuralgia, nerve pain, central pain, peripheral nerve pain, tDCS. The selected studies were full articles written in Portuguese, English, or Spanish with at least one control group, and no less than one pre- or post-intervention variable, with the exclusion of case studies or case series, animal model studies, and studies with combined therapy...
March 30, 2018: Neurological Research
https://www.readbyqxmd.com/read/29608807/long-term-effect-of-peripheral-nerve-field-stimulation-as-add-on-therapy-to-spinal-cord-stimulation-to-treat-low-back-pain-in-failed-back-surgery-syndrome-patients-a-12-month-follow-up-of-a-randomized-controlled-study
#4
Eric-Jan J A A van Gorp, Onno Teernstra, Hans J Aukes, Tanja Hamm-Faber, Katja Bürger, Jan Willem Kallewaard, Geert Spincemaille, Johannes W L C Schapendonk, Leon Vonhögen, Ewald Bronkhorst, Kris C P Vissers
OBJECTIVE: Different approaches in neuromodulation have been used to treat chronic low back pain in failed back surgery syndrome (FBSS) patients. We previously randomized 52 FBSS patients to be treated with spinal cord stimulation (SCS) and additional peripheral nerve field stimulation (PNFS) or SCS alone. At three months, we found a significant reduction of back pain in the PNFS-SCS group compared to the SCS group. In the subsequent open phase part of the study, all patients received optimal SCS and PNFS simultaneously...
April 2, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29618971/novel-neurostimulation-of-autonomic-pelvic-nerves-overcomes-bladder-sphincter-dyssynergia
#5
Wendy Yen Xian Peh, Roshini Mogan, Xin Yuan Thow, Soo Min Chua, Astrid Rusly, Nitish V Thakor, Shih-Cheng Yen
The disruption of coordination between smooth muscle contraction in the bladder and the relaxation of the external urethral sphincter (EUS) striated muscle is a common issue in dysfunctional bladders. It is a significant challenge to overcome for neuromodulation approaches to restore bladder control. Bladder-sphincter dyssynergia leads to undesirably high bladder pressures, and poor voiding outcomes, which can pose life-threatening secondary complications. Mixed pelvic nerves are potential peripheral targets for stimulation to treat dysfunctional bladders, but typical electrical stimulation of pelvic nerves activates both the parasympathetic efferent pathway to excite the bladder, as well as the sensory afferent pathway that causes unwanted sphincter contractions...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29623108/electrical-neuromodulation-in-the-management-of-lower-urinary-tract-dysfunction-evidence-experience-and-future-prospects
#6
REVIEW
Alejandro Abello, Anurag K Das
Lower urinary tract dysfunction (LUTD) is common and causes a spectrum of morbidity and decreased quality of life (QoL) for patients. LUTD can range from urinary retention to urge incontinence, and includes a variety of syndromes, with the most common and widely recognized being overactive bladder (OAB). The classic treatments of LUTD and OAB comprise different strategies including behavioral therapies, medications and minimally invasive or invasive surgical procedures. Generally, once patients have tried behavioral modifications and oral medical therapy, and have not experienced adequate relief of their symptoms, the next step is to consider minimally invasive therapies...
May 2018: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29628873/combined-rtms-fmri-studies-an-overlooked-resource-in-animal-models
#7
REVIEW
Bhedita J Seewoo, Sarah J Etherington, Kirk W Feindel, Jennifer Rodger
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique, which has brain network-level effects in healthy individuals and is also used to treat many neurological and psychiatric conditions in which brain connectivity is believed to be abnormal. Despite the fact that rTMS is being used in a clinical setting and animal studies are increasingly identifying potential cellular and molecular mechanisms, little is known about how these mechanisms relate to clinical changes. This knowledge gap is amplified by non-overlapping approaches used in preclinical and clinical rTMS studies: preclinical studies are mostly invasive, using cellular and molecular approaches, while clinical studies are non-invasive, including functional magnetic resonance imaging (fMRI), TMS electroencephalography (EEG), positron emission tomography (PET), and behavioral measures...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29116936/neurophysiological-aspects-of-the-trigeminal-sensory-system-an-update
#8
Frederic Van der Cruyssen, Constantinus Politis
The trigeminal system is one of the most complex cranial nerve systems of the human body. Research on it has vastly grown in recent years and concentrated more and more on molecular mechanisms and pathophysiology, but thorough reviews on this topic are lacking, certainly on the normal physiology of the trigeminal sensory system. Here we review the current literature on neurophysiology of the trigeminal nerve from peripheral receptors up to its central projections toward the somatosensory cortex. We focus on the most recent scientific discoveries and describe historical relevant research to substantiate further...
February 23, 2018: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/29572165/using-recent-bci-literature-to-deepen-our-understanding-of-clinical-neurofeedback-a-short-review
#9
REVIEW
Camille Jeunet, Fabien Lotte, Jean-Marie Batail, Pierre Philip, Jean-Arthur Micoulaud Franchi
In their recent paper, Alkoby et al. (2017) provide the readership with an extensive and very insightful review of the factors influencing NeuroFeedback (NF) performance. These factors are drawn from both the NF literature and the Brain-computer interface (BCI) literature. Our short review aims to complement Alkoby et al.'s review by reporting recent additions to the BCI literature. The object is to highlight this literature and discuss its potential relevance and usefulness to better understand the processes underlying NF and further improve the design of clinical trials assessing NF efficacy...
March 20, 2018: Neuroscience
https://www.readbyqxmd.com/read/29513044/pain-chronification-what-should-a-non-pain-medicine-specialist-know
#10
Bart Morlion, Flaminia Coluzzi, Dominic Aldington, Magdalena Kocot-Kepska, Joseph Pergolizzi, Ana Cristina Mangas, Karsten Ahlbeck, Eija Kalso
OBJECTIVE: Pain is one of the most common reasons for an individual to consult their primary care physician, with most chronic pain being treated in the primary care setting. However, many primary care physicians/non-pain medicine specialists lack enough awareness, education and skills to manage pain patients appropriately, and there is currently no clear, common consensus/formal definition of "pain chronification". METHODS: This article, based on an international Change Pain Chronic Advisory Board meeting which was held in Wiesbaden, Germany, in October 2016, provides primary care physicians/non-pain medicine specialists with a narrative overview of pain chronification, including underlying physiological and psychosocial processes, predictive factors for pain chronification, a brief summary of preventive strategies, and the role of primary care physicians and non-pain medicine specialists in the holistic management of pain chronification...
April 12, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29528455/lumbar-sympathetic-plexus-block-as-a-treatment-for-postamputation-pain-methodology-for-a-randomized-controlled-trial
#11
Zachary L McCormick, Andrew Hendrix, David Dayanim, Bryan Clay, Amy Kirsling, Norman Harden
Objective: We present a technical protocol for rigorous assessment of patient-reported outcomes and psychophysical testing relevant to lumbar sympathetic blocks for the treatment of postamputation pain (PAP). This description is intended to inform future prospective investigation. Design: Series of four participants from a blinded randomized sham-controlled trial. Setting: Tertiary, urban, academic pain medicine center. Subjects: Four participants with a single lower limb amputation and associated chronic PAP...
March 8, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29556832/spinal-cord-stimulation-mild-procedure-and-regenerative-medicine-novel-interventional-nonopioid-therapies-in-chronic-pain
#12
REVIEW
Ken P Ehrhardt, Susan M Mothersele, Andrew J Brunk, Jeremy B Green, Mark R Jones, Craig B Billeaud, Alan David Kaye
PURPOSE OF REVIEW: Chronic pain is a highly prevalent condition affecting millions of individuals. RECENT FINDINGS: In recent years, newer treatments have emerged that are changing the way clinicians treat pain pathogenesis, including novel nonopioid strategies. In this regard, spinal cord stimulation, the MILD procedure, and regenerative medicine have shown promise. This review summarizes recent literature on these three emerging treatment strategies. The results of this review suggest that under certain conditions, spinal cord stimulation, the MILD procedure, and regenerative medicine can be effective treatment modalities...
March 19, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29567583/event-related-brain-potentials-elicited-by-high-speed-cooling-of-the-skin-a-robust-and-non-painful-method-to-assess-the-spinothalamic-system-in-humans
#13
Roxane De Keyser, Emanuel N van den Broeke, Arthur Courtin, André Dufour, André Mouraux
OBJECTIVE: To investigate whether cool-evoked potentials (CEP) elicited by brisk innocuous cooling of the skin could serve as an alternative to laser-evoked potentials (LEP), currently considered as the best available neurophysiological tool to assess the spinothalamic tract and diagnose neuropathic pain. METHODS: A novel device made of micro-Peltier elements and able to cool the skin at -300 °C/s was used to record CEPs elicited by stimulation of the hand dorsum in 40 healthy individuals, characterize the elicited responses, and assess their signal-to-noise ratio...
March 8, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29021927/split-femoral-nerve-due-to-psoas-tertius-muscle-a-review-with-other-cases-of-variant-muscles-traversing-the-femoral-nerve
#14
Shehzad Khalid, Joe Iwanaga, Marios Loukas, R Shane Tubbs
Leg pain from lumbar disc herniation is a common presentation. However, certain muscular and peripheral nerve variants may present similarly and represent an unrecognized etiology of femoral nerve dysfunction. Such cases might affect the outcome of specific treatment regimes. Therefore, recognition of these variations in anatomy may be useful to the clinician when treating the patient with medically refractory lower limb pain. Some reports have reported variant slips of the psoas and iliacus muscles, which may split the femoral nerve causing a potential risk for nerve entrapment...
August 9, 2017: Curēus
https://www.readbyqxmd.com/read/29515350/a-pilot-study-of-peripheral-muscle-magnetic-stimulation-as-add-on-treatment-to-repetitive-transcranial-magnetic-stimulation-in-chronic-tinnitus
#15
Veronika Vielsmeier, Martin Schecklmann, Winfried Schlee, Peter M Kreuzer, Timm B Poeppl, Rainer Rupprecht, Berthold Langguth, Astrid Lehner
While brain stimulation techniques have been examined as treatment options for chronic tinnitus for many years, they have recently been extended to multimodal treatment approaches. As chronic tinnitus is often accompanied by comorbid muscular tension in the neck and back, we performed a one-arm pilot study to explore the feasibility of a new multimodal treatment approach. In detail, repetitive peripheral magnetic stimulation (rPMS) of the back was performed before and after each session of repetitive transcranial magnetic stimulation (rTMS) of the brain...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29465328/mechano-and-thermosensitivity-of-injured-muscle-afferents-20-to-80-days-after-nerve-injury
#16
Jan Tode, Irina Kirillova-Woytke, Vanessa H Rausch, Ralf Baron, Wilfrid Jänig
Chronic injury of limb nerves leading to neuropathic pain affects deep somatic nerves. Here the functional properties of injured afferent fibers in the lateral gastrocnemius-soleus nerve were investigated 20 and 80 days after suturing the central stump of this muscle nerve to the distal stump of the sural nerve in anesthetized rats. Neurophysiological recordings were made from afferent axons identified in either the sciatic nerve (87 A-, 63 C-fibers) or the dorsal root L4/L5 (52 A-, 26 C-fibers) by electrical stimulation of the injured nerve...
May 1, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29494416/pathophysiological-mechanisms-of-neuropathic-pain-comparison-of-sensory-phenotypes-in-patients-and-human-surrogate-pain-models
#17
Jan Vollert, Walter Magerl, Ralf Baron, Andreas Binder, Elena K Enax-Krumova, Gerd Geisslinger, Janne Gierthmühlen, Florian Henrich, Philipp Hüllemann, Thomas Klein, Jörn Lötsch, Christoph Maier, Bruno Oertel, Sigrid Schuh-Hofer, Thomas R Tölle, Rolf-Detlef Treede
As an indirect approach to relate previously identified sensory phenotypes of patients suffering from peripheral neuropathic pain to underlying mechanisms, we used a published sorting algorithm to estimate the prevalence of denervation, peripheral and central sensitization in 657 healthy subjects undergoing experimental models of nerve block (NB) (compression block and topical lidocaine), primary hyperalgesia (PH) (sunburn and topical capsaicin), or secondary hyperalgesia (intradermal capsaicin and electrical high-frequency stimulation), and in 902 patients suffering from neuropathic pain...
February 24, 2018: Pain
https://www.readbyqxmd.com/read/29445295/the-effect-of-exercise-frequency-on-neuropathic-pain-and-pain-related-cellular-reactions-in-the-spinal-cord-and-midbrain-in-a-rat-sciatic-nerve-injury-model
#18
Megumi Sumizono, Harutoshi Sakakima, Shotaro Otsuka, Takuto Terashi, Kazuki Nakanishi, Koki Ueda, Seiya Takada, Kiyoshi Kikuchi
Background: Exercise regimens are established methods that can relieve neuropathic pain. However, the relationship between frequency and intensity of exercise and multiple cellular responses of exercise-induced alleviation of neuropathic pain is still unclear. We examined the influence of exercise frequency on neuropathic pain and the intracellular responses in a sciatic nerve chronic constriction injury (CCI) model. Materials and methods: Rats were assigned to four groups as follows: CCI and high-frequency exercise (HFE group), CCI and low-frequency exercise (LFE group), CCI and no exercise (No-Ex group), and naive animals (control group)...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29490076/advancing-simulation-based-education-in-pain-medicine
#19
Naileshni Singh, Alison A Nielsen, David J Copenhaver, Samir J Sheth, Chin-Shang Li, Scott M Fishman
Background: The Accreditation Council for Graduate Medical Education (ACGME) has recently implemented milestones and competencies as a framework for training fellows in Pain Medicine, but individual programs are left to create educational platforms and assessment tools that meet ACGME standards. Objectives: In this article, we discuss the concept of milestone-based competencies and the inherent challenges for implementation in pain medicine. We consider simulation-based education (SBE) as a potential tool for the field to meet ACGME goals through advancing novel learning opportunities, engaging in clinically relevant scenarios, and mastering technical and nontechnical skills...
February 27, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29487504/potential-mechanisms-underlying-centralized-pain-and-emerging-therapeutic-interventions
#20
REVIEW
Olivia C Eller-Smith, Andrea L Nicol, Julie A Christianson
Centralized pain syndromes are associated with changes within the central nervous system that amplify peripheral input and/or generate the perception of pain in the absence of a noxious stimulus. Examples of idiopathic functional disorders that are often categorized as centralized pain syndromes include fibromyalgia, chronic pelvic pain syndromes, migraine, and temporomandibular disorder. Patients often suffer from widespread pain, associated with more than one specific syndrome, and report fatigue, mood and sleep disturbances, and poor quality of life...
2018: Frontiers in Cellular Neuroscience
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