Inge Mick, Jim Myers, Anna C Ramos, Paul R A Stokes, David Erritzoe, Alessandro Colasanti, Roger N Gunn, Eugenii A Rabiner, Graham E Searle, Adam D Waldman, Mark C Parkin, Alan D Brailsford, José C F Galduróz, Henrietta Bowden-Jones, Luke Clark, David J Nutt, Anne R Lingford-Hughes
Pathological gambling is a psychiatric disorder and the first recognized behavioral addiction, with similarities to substance use disorders but without the confounding effects of drug-related brain changes. Pathophysiology within the opioid receptor system is increasingly recognized in substance dependence, with higher mu-opioid receptor (MOR) availability reported in alcohol, cocaine and opiate addiction. Impulsivity, a risk factor across the addictions, has also been found to be associated with higher MOR availability...
June 2016: Neuropsychopharmacology