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dementia

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299 papers 25 to 100 followers
https://www.readbyqxmd.com/read/28063859/assessing-palliative-care-content-in-dementia-care-guidelines-a-systematic-review
#1
REVIEW
Pamela Durepos, Abigail Wickson-Griffiths, Afeez Abiola Hazzan, Sharon Kaasalainen, Vasilia Vastis, Lisa Battistella, Alexandra Papaioannou
CONTEXT: Families of persons with dementia continue to report unmet needs during end-of-life. Strategies to improve care and quality of life for persons with dementia include development of clinical practice guidelines (CPG) and an integrative palliative approach. OBJECTIVES: We aimed to assess palliative care content in dementia CPGs in order to identify the presence or limitations of recommendations and discussion pertaining to common issues or domains affected by illness as described by the Canadian Hospice Palliative Care 'Square of Care'...
January 4, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28177148/when-walking-becomes-wandering-representing-the-fear-of-the-fourth-age
#2
Katherine Brittain, Cathrine Degnen, Grant Gibson, Claire Dickinson, Louise Robinson
Dementia is linked to behavioural changes that are perceived as challenging to care practices. One such behavioural change is 'wandering', something that is often deeply feared by carers and by people with dementia themselves. Understanding how behavioural changes like wandering are experienced as problematic is critically important in current discussions about the behavioural and psychological symptoms of dementia. In this article we draw on our secondary analysis of qualitative interviews and focus groups with carers of people with dementia to critically question 'when does walking become wandering'? Drawing on theoretical perspectives from anthropology, sociology and human geography to explore experiences of carers and of people with dementia, we argue that a conceptual shift occurs in how pedestrian activity, usually represented as something purposeful, meaningful and healthy (walking) is seen as something threatening that needs managing (wandering)...
February 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28117918/cognitive-impairment-and-charles-bonnet-syndrome-a-prospective-study
#3
Gregor Russell, Robert Harper, Harry Allen, Robert Baldwin, Alistair Burns
OBJECTIVES: Charles Bonnet syndrome (CBS) is a common cause of visual hallucinations in older people. The relationship between CBS and cognitive impairment is unclear, but anecdotal reports exist of dementia emerging in patients diagnosed with CBS. This work set out to determine if there is an increased incidence of dementia, and increased severity of cognitive impairment, in people with CBS compared to controls from the same clinical setting. METHOD: People over 65 attending low-vision and glaucoma clinics, and a cohort of age-matched controls, underwent a psychiatric assessment...
January 24, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28150348/management-of-acute-ischaemic-stroke-in-patients-with-dementia
#4
REVIEW
A Subic, P Cermakova, B Norrving, B Winblad, M von Euler, M G Kramberger, M Eriksdotter, S Garcia-Ptacek
An estimated 10% of stroke patients have an underlying dementia. As a consequence, health professionals often face the challenge of managing patients with dementia presenting with an acute stroke. Patients with dementia are less likely to receive thrombolysis (0.56-10% vs. 1-16% thrombolysis rates in the general population), be admitted to a stroke unit or receive some types of care. Anticoagulation for secondary stroke prevention is sometimes withheld, despite dementia not being listed as an exclusion criterion in current guidelines...
February 2, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28153848/cjd-mimics-and-chameleons
#5
REVIEW
Simon Mead, Peter Rudge
Rapidly progressive dementia mimicking Creutzfeldt-Jakob disease (CJD) is a relatively rare presentation but a rewarding one to become familiar with, as the potential diagnoses range from the universally fatal to the completely reversible. Patients require urgent decisions about assessment and investigation and have quickly evolving needs for treatments and support, through symptom management and end-of-life care in most cases. We have based this pragmatic review on the experiences of a specialist prion referral centre in the UK, which, unsurprisingly, is strongly biased towards seeing patients with CJD...
February 2, 2017: Practical Neurology
https://www.readbyqxmd.com/read/28161989/-it-brings-it-all-back-all-those-good-times-it-makes-me-go-close-to-tears-creating-digital-personalised-stories-with-people-who-have-dementia
#6
Valerie Critten, Natalia Kucirkova
The purpose of these three case studies was to analyse and theoretically explain the contribution of digital multimedia personalisation to stimulate and share long-term memories of people who live with mild to moderate dementia. We investigated how the use of a freely available iPad app can, in a supporting context, facilitate the creation of personalised multimedia stories, including the participants' audio recordings, texts and photos of items, places or people important to them. Three people who were recruited from a club for people living with dementia created personalised multimedia stories using their own photographs and/or pictures downloaded from the internet, with written captions and audio-recorded voiceovers...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28176148/avicenna-s-pharmacological-approach-to-memory-enhancement
#7
REVIEW
Roja Rahimi, Shahrzad Irannejad, Maryam Noroozian
In recent decades, the number of patients with dementia has significantly risen. Current treatments for dementia are not curative and there still is place for development of medications. Throughout the ages, several medical disciplines have systematized and codified medical knowledge acquired throughout centuries of trial and error. Revisiting these disciplines might help in gaining insight for development of medications and other therapeutic strategies. The present study aims to show the possible benefits of an immanent understanding of the approach towards memory and dementias taken by humoral medical discourse in the Islamicate world...
February 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28177144/ageing-dementia-and-the-social-mind-past-present-and-future-perspectives
#8
Paul Higgs, Chris Gilleard
Accompanying the ageing of contemporary ageing societies is an increase in age associated morbidity, with dementia having an important impact. Mental frailty in later life is a source of fear for many and a major policy concern to all those concerned with health and welfare services. This introduction to the special issue on 'Ageing, dementia and the social mind' situates the selected papers within the context of debates about dementia and its social relations. In particular it draws attention to the importance of the social imaginary of the fourth age and what this means for the issue of personhood, care, social representations of dementia and its social contextualisation...
February 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28168012/nutrition-and-age-ing-focusing-on-alzheimer-s-disease
#9
REVIEW
Giulia Abate, Mariagrazia Marziano, Wiramon Rungratanawanich, Maurizio Memo, Daniela Uberti
Recently, the role of food and nutrition in preventing or delaying chronic disability in the elderly population has received great attention. Thanks to their ability to influence biochemical and biological processes, bioactive nutrients are considered modifiable factors capable of preserving a healthy brain status. A diet rich in vitamins and polyphenols and poor in saturated fatty acids has been recommended. In the prospective of a healthy diet, cooking methods should be also considered. In fact, cooking procedures can modify the original dietary content, contributing not only to the loss of healthy nutrients, but also to the formation of toxins, including advanced glycation end products (AGEs)...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28168970/strategies-to-improve-dental-health-in-elderly-patients-with-cognitive-impairment-a-systematic-review
#10
REVIEW
Natalia S Rozas, June M Sadowsky, Cameron B Jeter
BACKGROUND: Cognitive impairment is the gradual loss of one's ability to learn, remember, pay attention, and make decisions. Cognitively impaired elderly people are a challenging patient population for dental health care professionals and may be at higher risk of developing oral health diseases. The authors systematically reviewed interventions effective at improving dental health in patients with cognitive impairment and described research gaps remaining. TYPES OF STUDIES REVIEWED: In a comprehensive search of multiple databases, the authors identified 2,255 studies published in the English language from 1995 through March 2016...
February 3, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28188439/the-missing-link-between-sleep-disorders-and-age-related-dementia-recent-evidence-and-plausible-mechanisms
#11
REVIEW
Feng Zhang, Rujia Zhong, Song Li, Raymond Chuen-Chung Chang, Weidong Le
Sleep disorders are among the most common clinical problems and possess a significant concern for the geriatric population. More importantly, while around 40% of elderly adults have sleep-related complaints, sleep disorders are more frequently associated with co-morbidities including age-related neurodegenerative diseases and mild cognitive impairment. Recently, increasing evidence has indicated that disturbed sleep may not only serve as the consequence of brain atrophy, but also contribute to the pathogenesis of dementia and, therefore, significantly increase dementia risk...
February 10, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28103749/clinical-practice-with-anti-dementia-drugs-a-revised-third-consensus-statement-from-the-british-association-for-psychopharmacology
#12
John T O'Brien, Clive Holmes, Matthew Jones, Roy Jones, Gill Livingston, Ian McKeith, Peter Mittler, Peter Passmore, Craig Ritchie, Louise Robinson, Elizabeth L Sampson, John-Paul Taylor, Alan Thomas, Alistair Burns
The British Association for Psychopharmacology coordinated a meeting of experts to review and revise its previous 2011 guidelines for clinical practice with anti-dementia drugs. As before, levels of evidence were rated using accepted standards which were then translated into grades of recommendation A-D, with A having the strongest evidence base (from randomised controlled trials) and D the weakest (case studies or expert opinion). Current clinical diagnostic criteria for dementia have sufficient accuracy to be applied in clinical practice (B) and both structural (computed tomography and magnetic resonance imaging) and functional (positron emission tomography and single photon emission computerised tomography) brain imaging can improve diagnostic accuracy in particular situations (B)...
February 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28099083/update-on-alzheimer-s-disease-therapy-and-prevention-strategies
#13
W Vallen Graham, Alessandra Bonito-Oliva, Thomas P Sakmar
Alzheimer's disease (AD) is the primary cause of age-related dementia. Effective strategies to prevent and treat AD remain elusive despite major efforts to understand its basic biology and clinical pathophysiology. Significant investments in therapeutic drug discovery programs over the past two decades have yielded some important insights but no blockbuster drugs to alter the course of disease. Because significant memory loss and cognitive decline are associated with neuron death and loss of gray matter, especially in the frontal cortex and hippocampus, some focus in drug development has shifted to early prevention of cellular pathology...
January 14, 2017: Annual Review of Medicine
https://www.readbyqxmd.com/read/25420446/dextromethorphan-quinidine-a-review-of-its-use-in-adults-with-pseudobulbar-affect
#14
REVIEW
Lily P H Yang, Emma D Deeks
Fixed-dose dextromethorphan/quinidine capsules (Nuedexta(®)) utilize quinidine to inhibit the metabolism of dextromethorphan, enabling high plasma dextromethorphan concentrations to be reached without using a larger dose of the drug. The drug combination is the first treatment to be approved for pseudobulbar affect (PBA), a condition of contextually inappropriate/exaggerated emotional expression that often occurs in adults with neurological damage conditions, such as amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), stroke, traumatic brain injury, Alzheimer's disease or Parkinson's disease...
January 2015: Drugs
https://www.readbyqxmd.com/read/28041588/diagnosing-early-cognitive-decline-when-how-and-for-whom
#15
REVIEW
Charlotte L Allan, Sophie Behrman, Klaus P Ebmeier, Vyara Valkanova
Mild cognitive impairment (MCI) is a term used to describe cognitive impairment in one or more cognitive domains that is greater than any expected age-related changes, but not of the magnitude to warrant a diagnosis of dementia. This review considers how early cognitive decline is diagnosed, focusing on the use of neuropsychological tests and neuroimaging, as well as the differential diagnosis. Potential treatments, including secondary prevention, post-diagnostic support and self-help are discussed. Finally, medico-legal matters such as driving, lasting power of attorney and employment are outlined...
February 2017: Maturitas
https://www.readbyqxmd.com/read/27932869/person-centered-dementia-care-current-perspectives
#16
REVIEW
Jill Manthorpe, Kritika Samsi
Person-centered dementia care is widely accepted as a value-based commitment to supporting people with dementia and is a guiding principle in care services. Policy ambitions to put people at the center of their own care are being developed internationally. These may be seen as part of the evolution of person-centered care which has its origins in critical perspectives on practice and social responses to people with dementia. In England, one further development of person-centered care has been personalization - a government policy to extend individuals' choice and control over their social care and, latterly, ways to meet their health care needs...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28017516/inappropriate-sexual-behaviors-among-community-dwelling-patients-with-dementia
#17
Marco Canevelli, Flaminia Lucchini, Carlo Garofalo, Giuseppina Talarico, Alessandro Trebbastoni, Fabrizia D'Antonio, Letizia Imbriano, Patrizia Velotti, Carlo de Lena, Marina Gasparini, Giuseppe Bruno
OBJECTIVE: Inappropriate sexual behaviors (ISBs) represent challenging and stressful manifestations of dementia and are highly burdening for patients, families, and healthcare providers. Nevertheless, ISBs have so far attracted limited clinical and scientific interest compared with other neuropsychiatric symptoms occurring in dementing illnesses. The authors aimed to systematically investigate the prevalence and characteristics of ISBs in a population of patients with dementia attending a memory clinic...
December 2, 2016: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28024093/oral-hygiene-in-the-elderly-with-different-degrees-of-cognitive-impairment-and-dementia
#18
José Antonio Gil-Montoya, Inés Sánchez-Lara, Cristobal Carnero-Pardo, Francisco Fornieles-Rubio, Juan Montes, Rocío Barrios, Miguel Angel Gonzalez-Moles, Manuel Bravo
The control of bacterial dental plaque through daily oral hygiene is essential to prevent oral diseases such as caries or periodontal disease, especially in at-risk populations, including the elderly with mild cognitive impairment and dementia. The aim of this study was to determine the association between different levels of cognitive impairment and dementia in an elderly population and their capacity to maintain adequate oral hygiene. A case-control study (elderly with versus without mild cognitive impairment or dementia) was performed in Granada, Spain...
December 26, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28025173/does-music-therapy-enhance-behavioral-and-cognitive-function-in-elderly-dementia-patients-a-systematic-review-and-meta-analysis
#19
REVIEW
Yingshi Zhang, Jiayi Cai, Li An, Fuhai Hui, Tianshu Ren, Hongda Ma, Qingchun Zhao
Demographic aging is a worldwide phenomenon, cognitive and behavioral impairment is becoming global burden of nerve damage. However, the effect of pharmacological treatment is not satisfying. Therefore, we analyzed the efficacy of music therapy in elderly dementia patients, and if so, whether music therapy can be used as first-line non-pharmacological treatment. A comprehensive literature search was performed on PubMed, EMbase and the Cochrane Library from inception to September 2016. A total of 34 studies (42 analyses, 1757 subjects) were included; all of them had an acceptable quality based on the PEDro and CASP scale scores...
December 23, 2016: Ageing Research Reviews
https://www.readbyqxmd.com/read/25899711/memantine-extended-release-28-mg-once-daily-a-review-of-its-use-in-alzheimer-s-disease
#20
REVIEW
Greg L Plosker
Memantine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that is a well-established treatment option for moderate to severe dementia of the Alzheimer's type, either alone or in combination with cholinesterase inhibitors. The immediate-release (IR) formulations of memantine (tablets and oral solution) have been available in numerous countries, including the USA, for more than a decade and are administered orally twice daily at a maximum recommended total daily dosage of 20 mg/day. The memantine extended-release (ER) (Namenda XR(®)) 28 mg once-daily capsule formulation was approved in the USA in 2010 and became available more recently...
May 2015: Drugs
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