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RANDOMIZED CONTROLLED TRIAL
Andrew W Kirkpatrick, Derek J Roberts, Peter D Faris, Chad G Ball, Paul Kubes, Corina Tiruta, Zhengwen Xiao, Jessalyn K Holodinsky, Paul B McBeth, Christopher J Doig, Craig N Jenne
OBJECTIVE: To determine whether active negative pressure peritoneal therapy with the ABThera temporary abdominal closure device reduces systemic inflammation after abbreviated laparotomy. BACKGROUND: Excessive systemic inflammation after abdominal injury or intra-abdominal sepsis is associated with poor outcomes. METHODS: We conducted a single-center, randomized controlled trial. Forty-five adults with abdominal injury (46.7%) or intra-abdominal sepsis (52...
July 2015: Annals of Surgery
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