collection
MENU ▼
Read by QxMD icon Read
search

Cardiovascular risk prediction and prevention

shared collection
490 papers 100 to 500 followers
By Jamie Jarmul Md / PhD student at UNC - Chapel Hill, PhD in Health Policy and Management
https://www.readbyqxmd.com/read/30141213/the-impact-of-clinical-vs-administrative-claims-coding-on-hospital-risk-adjusted-outcomes
#1
MULTICENTER STUDY
Emily C O'Brien, Shuang Li, Laine Thomas, Tracy Y Wang, Matthew T Roe, Eric D Peterson
BACKGROUND: Comorbid condition and hospital risk-adjusted outcomes prevalence were compared based on clinical registry vs administrative claims data. HYPOTHESIS: Risk-adjusted outcomes will vary depending on the source of comorbidity data used. METHODS: Clinical data from hospitalized Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the American College of Cardiology/American Heart Association (ACC/AHA) Guidelines (CRUSADE) non-ST-segment elevation myocardial infarction (NSTEMI) patients ≥65 years was linked to Medicare claims...
September 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29490332/reducing-racial-ethnic-disparities-in-cardiovascular-genetic-testing
#2
Lisa M Dellefave-Castillo, Megan J Puckelwartz, Elizabeth M McNally
No abstract text is available yet for this article.
April 1, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29459468/genetics-lifestyle-and-low-density-lipoprotein-cholesterol-in-young-and-apparently-healthy-women
#3
Jan-Willem Balder, Antoine Rimbert, Xiang Zhang, Martijn Viel, Roan Kanninga, Freerk van Dijk, Peter Lansberg, Richard Sinke, Jan Albert Kuivenhoven
BACKGROUND: Atherosclerosis starts in childhood but low-density lipoprotein cholesterol (LDL-C), a causal risk factor, is mostly studied and dealt with when clinical events have occurred. Women are usually affected later in life than men and are underdiagnosed, undertreated, and understudied in cardiovascular trials and research. This study aims at a better understanding of lifestyle and genetic factors that affect LDL-C in young women. METHODS: We randomly selected for every year of age 8 women with LDL-C ≤1st percentile (≤50 mg/dL) and 8 women with LDL-C ≥99th percentile (≥186 mg/dL) from 28 000 female participants aged between 25 to 40 years of a population-based cohort study...
February 20, 2018: Circulation
https://www.readbyqxmd.com/read/27189013/opportunities-and-challenges-in-developing-risk-prediction-models-with-electronic-health-records-data-a-systematic-review
#4
REVIEW
Benjamin A Goldstein, Ann Marie Navar, Michael J Pencina, John P A Ioannidis
OBJECTIVE: Electronic health records (EHRs) are an increasingly common data source for clinical risk prediction, presenting both unique analytic opportunities and challenges. We sought to evaluate the current state of EHR based risk prediction modeling through a systematic review of clinical prediction studies using EHR data. METHODS: We searched PubMed for articles that reported on the use of an EHR to develop a risk prediction model from 2009 to 2014. Articles were extracted by two reviewers, and we abstracted information on study design, use of EHR data, model building, and performance from each publication and supplementary documentation...
January 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/27436868/moving-beyond-regression-techniques-in-cardiovascular-risk-prediction-applying-machine-learning-to-address-analytic-challenges
#5
REVIEW
Benjamin A Goldstein, Ann Marie Navar, Rickey E Carter
Risk prediction plays an important role in clinical cardiology research. Traditionally, most risk models have been based on regression models. While useful and robust, these statistical methods are limited to using a small number of predictors which operate in the same way on everyone, and uniformly throughout their range. The purpose of this review is to illustrate the use of machine-learning methods for development of risk prediction models. Typically presented as black box approaches, most machine-learning methods are aimed at solving particular challenges that arise in data analysis that are not well addressed by typical regression approaches...
June 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28418481/comparison-of-recommended-eligibility-for-primary-prevention-statin-therapy-based-on-the-us-preventive-services-task-force-recommendations-vs-the-acc-aha-guidelines
#6
COMPARATIVE STUDY
Neha J Pagidipati, Ann Marie Navar, Hillary Mulder, Allan D Sniderman, Eric D Peterson, Michael J Pencina
Importance: There are important differences among guideline recommendations for using statin therapy in primary prevention. New recommendations from the US Preventive Services Task Force (USPSTF) emphasize therapy based on the presence of 1 or more cardiovascular disease (CVD) risk factors and a 10-year global CVD risk of 10% or greater. Objective: To determine the difference in eligibility for primary prevention statin treatment among US adults, assuming full application of USPSTF recommendations compared with the American College of Cardiology/American Heart Association (ACC/AHA) guidelines...
April 18, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29129260/lipid-management-in-contemporary-community-practice-results-from-the-provider-assessment-of-lipid-management-palm-registry
#7
MULTICENTER STUDY
Ann Marie Navar, Tracy Y Wang, Shuang Li, Jennifer G Robinson, Anne C Goldberg, Salim Virani, Veronique L Roger, Peter W F Wilson, Joseph Elassal, L Veronica Lee, Eric D Peterson
BACKGROUND: The latest cholesterol guidelines have shifted focus from achieving low-density lipoprotein cholesterol (LDL-C) targets toward statin use and intensity guided by atherosclerotic cardiovascular disease (ASCVD) risk. METHODS: Statin use and intensity were evaluated in 5,905 statin-eligible primary or secondary prevention patients from 138 PALM Registry practices. RESULTS: Overall, 74.7% of eligible adults were on statins; only 42...
November 2017: American Heart Journal
https://www.readbyqxmd.com/read/29371200/lipid-testing-and-statin-dosing-after-acute-myocardial-infarction
#8
William T Wang, Anne Hellkamp, Jacob A Doll, Laine Thomas, Ann Marie Navar, Gregg C Fonarow, Howard M Julien, Eric D Peterson, Tracy Y Wang
BACKGROUND: The 2013 American College of Cardiology/American Heart Association cholesterol guidelines recommend high-intensity statins for patients after myocardial infarction (MI) rather than treating to a low-density lipoprotein cholesterol goal, as the previous ATP III (Adult Treatment Panel third report) guidelines had advised. METHODS AND RESULTS: To evaluate the frequency of postdischarge lipid testing and high-intensity statin use among MI patients discharged on a statin during the ATP III guidelines era, we linked ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry data to Medicare claims for 11 046 MI patients aged ≥65 years who were discharged alive on a statin from 347 hospitals (2007-2009)...
January 25, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29326185/enhancing-prescribing-of-guideline-recommended-medications-for-ischaemic-heart-diseases-a-systematic-review-and-meta-analysis-of-interventions-targeted-at-healthcare-professionals
#9
REVIEW
Thang Nguyen, Hoa Q Nguyen, Niken N Widyakusuma, Thao H Nguyen, Tam T Pham, Katja Taxis
OBJECTIVES: Ischaemic heart diseases (IHDs) are a leading cause of death worldwide. Although prescribing according to guidelines improves health outcomes, it remains suboptimal. We determined whether interventions targeted at healthcare professionals are effective to enhance prescribing and health outcomes in patients with IHDs. METHODS: We systematically searched PubMed and EMBASE for studies published between 1 January 2000 and 31 August 2017. We included original studies of interventions targeted at healthcare professionals to enhance prescribing guideline-recommended medications for IHDs...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/28687707/validity-of-cardiovascular-data-from-electronic-sources-the-multi-ethnic-study-of-atherosclerosis-and-healthlnk
#10
Faraz S Ahmad, Cheeling Chan, Marc B Rosenman, Wendy S Post, Daniel G Fort, Philip Greenland, Kiang J Liu, Abel N Kho, Norrina B Allen
BACKGROUND: Understanding the validity of data from electronic data research networks is critical to national research initiatives and learning healthcare systems for cardiovascular care. Our goal was to evaluate the degree of agreement of electronic data research networks in comparison with data collected by standardized research approaches in a cohort study. METHODS: We linked individual-level data from MESA (Multi-Ethnic Study of Atherosclerosis), a community-based cohort, with HealthLNK, a 2006 to 2012 database of electronic health records from 6 Chicago health systems...
September 26, 2017: Circulation
https://www.readbyqxmd.com/read/29454784/coronary-artery-calcium-scores-and-atherosclerotic-cardiovascular-disease-risk-stratification-in-smokers-mesa
#11
Adam Leigh, John W McEvoy, Parveen Garg, J Jeffrey Carr, Veit Sandfort, Elizabeth C Oelsner, Matthew Budoff, David Herrington, Joseph Yeboah
OBJECTIVES: This study assessed the utility of the pooled cohort equation (PCE) and/or coronary artery calcium (CAC) for atherosclerotic cardiovascular disease (ASCVD) risk assessment in smokers, especially those who were lung cancer screening eligible (LCSE). BACKGROUND: The U.S. Preventive Services Task Force recommended and the Centers for Medicare & Medicaid Services currently pays for annual screening for lung cancer with low-dose computed tomography scans in a specified group of cigarette smokers...
February 14, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29348251/reducing-cardiovascular-disparities-through-community-engaged-implementation-research-a-national-heart-lung-and-blood-institute-workshop-report
#12
George A Mensah, Richard S Cooper, Anna Maria Siega-Riz, Lisa A Cooper, Justin D Smith, C Hendricks Brown, John M Westfall, Elizabeth O Ofili, LeShawndra N Price, Sonia Arteaga, Melissa C Green Parker, Cheryl R Nelson, Bradley J Newsome, Nicole Redmond, Rebecca A Roper, Bettina M Beech, Jada L Brooks, Debra Furr-Holden, Samson Y Gebreab, Wayne H Giles, Regina Smith James, Tené T Lewis, Ali H Mokdad, Kari D Moore, Joseph E Ravenell, Al Richmond, Nancy E Schoenberg, Mario Sims, Gopal K Singh, Anne E Sumner, Roberto P Treviño, Karriem S Watson, M Larissa Avilés-Santa, Jared P Reis, Charlotte A Pratt, Michael M Engelgau, David C Goff, Eliseo J Pérez-Stable
Cardiovascular disparities remain pervasive in the United States. Unequal disease burden is evident among population groups based on sex, race, ethnicity, socioeconomic status, educational attainment, nativity, or geography. Despite the significant declines in cardiovascular disease mortality rates in all demographic groups during the last 50 years, large disparities remain by sex, race, ethnicity, and geography. Recent data from modeling studies, linked micromap plots, and small-area analyses also demonstrate prominent variation in cardiovascular disease mortality rates across states and counties, with an especially high disease burden in the southeastern United States and Appalachia...
January 19, 2018: Circulation Research
https://www.readbyqxmd.com/read/29284738/comparison-of-risk-factor-control-in-the-year-after-discharge-for-ischemic-stroke-versus-acute-myocardial-infarction
#13
COMPARATIVE STUDY
Dawn M Bravata, Joanne Daggy, Jared Brosch, Jason J Sico, Fitsum Baye, Laura J Myers, Christianne L Roumie, Eric Cheng, Jessica Coffing, Greg Arling
BACKGROUND AND PURPOSE: The Veterans Health Administration has engaged in quality improvement to improve vascular risk factor control. We sought to examine blood pressure (<140/90 mm Hg), lipid (LDL [low-density lipoprotein] cholesterol <100 mg/dL), and glycemic control (hemoglobin A1c <9%), in the year post-hospitalization for acute ischemic stroke or acute myocardial infarction (AMI). METHODS: We identified patients who were hospitalized (fiscal year 2011) with ischemic stroke, AMI, congestive heart failure, transient ischemic attack, or pneumonia/chronic obstructive pulmonary disease...
February 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29367334/2018-guidelines-for-the-early-management-of-patients-with-acute-ischemic-stroke-a-guideline-for-healthcare-professionals-from-the-american-heart-association-american-stroke-association
#14
REVIEW
William J Powers, Alejandro A Rabinstein, Teri Ackerson, Opeolu M Adeoye, Nicholas C Bambakidis, Kyra Becker, José Biller, Michael Brown, Bart M Demaerschalk, Brian Hoh, Edward C Jauch, Chelsea S Kidwell, Thabele M Leslie-Mazwi, Bruce Ovbiagele, Phillip A Scott, Kevin N Sheth, Andrew M Southerland, Deborah V Summers, David L Tirschwell
BACKGROUND AND PURPOSE: The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations for clinicians caring for adult patients with acute arterial ischemic stroke in a single document. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators. These guidelines supersede the 2013 guidelines and subsequent updates. METHODS: Members of the writing group were appointed by the American Heart Association Stroke Council's Scientific Statements Oversight Committee, representing various areas of medical expertise...
March 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29386279/prescription-of-antihypertensive-medication-at-discharge-influences-survival-following-stroke
#15
Nadine E Andrew, Joosup Kim, Amanda G Thrift, Monique F Kilkenny, Natasha A Lannin, Craig S Anderson, Geoffrey A Donnan, Kelvin Hill, Sandy Middleton, Christopher Levi, Steven Faux, Rohan Grimley, Nisal Gange, Richard Geraghty, Sharan Ermel, Dominique A Cadilhac
OBJECTIVE: To investigate the risk of death from cardiovascular disease between patients who were and were not prescribed antihypertensive medication following stroke or TIA. METHODS: This was a large cohort study using routinely collected prospective data from the Australian Stroke Clinical Registry. Patients registered between 2009 and 2013 who were discharged to the community or rehabilitation were included. Cases were linked to the National Death Index to determine the date and cause of death...
February 27, 2018: Neurology
https://www.readbyqxmd.com/read/29341841/redefining-hypertension-assessing-the-new-blood-pressure-guidelines
#16
George Bakris, Matthew Sorrentino
Like physical guidelines designed to ensure that hikers stay on the safest path through tricky terrain, expert medical guidelines aim to steer clinicians toward best practices. The new Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults issued by the..
February 8, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/28505660/prevalence-of-elevated-cardiovascular-risks-in-young-adults-a-cross-sectional-analysis-of-national-health-and-nutrition-examination-surveys
#17
Krishna K Patel, Glen B Taksler, Bo Hu, Michael B Rothberg
Background: The 2013 cholesterol management guidelines from the American College of Cardiology and American Heart Association (ACC/AHA) recommend lipid screening in all adults older than 20 years to identify those at increased risk for atherosclerotic cardiovascular disease (ASCVD). Statins may be considered for patients with elevated 10-year risk (>5%) or a low-density lipoprotein cholesterol (LDL-C) level of 4.92 mmol/L (190 mg/dL) or greater. Objective: To describe the prevalence of elevated ASCVD risk among nondiabetic adults younger than 50 years...
June 20, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29273581/mortality-differences-associated-with-treatment-responses-in-cantos-and-fourier-insights-and-implications
#18
Paul M Ridker
No abstract text is available yet for this article.
April 24, 2018: Circulation
https://www.readbyqxmd.com/read/28616955/niacin-for-primary-and-secondary-prevention-of-cardiovascular-events
#19
REVIEW
Stefan Schandelmaier, Matthias Briel, Ramon Saccilotto, Kelechi K Olu, Armon Arpagaus, Lars G Hemkens, Alain J Nordmann
BACKGROUND: Nicotinic acid (niacin) is known to decrease LDL-cholesterol, and triglycerides, and increase HDL-cholesterol levels. The evidence of benefits with niacin monotherapy or add-on to statin-based therapy is controversial. OBJECTIVES: To assess the effectiveness of niacin therapy versus placebo, administered as monotherapy or add-on to statin-based therapy in people with or at risk of cardiovascular disease (CVD) in terms of mortality, CVD events, and side effects...
June 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28247847/risk-estimates-for-atherosclerotic-cardiovascular-disease-in-adults-with-congenital-heart-disease
#20
George K Lui, Ian S Rogers, Victoria Y Ding, Haley K Hedlin, Kirstie MacMillen, David J Maron, Christy Sillman, Anitra Romfh, Tara C Dade, Christiane Haeffele, Stafford R Grady, Doff B McElhinney, Daniel J Murphy, Susan M Fernandes
The adult with congenital heart disease (CHD) is at risk of developing atherosclerotic cardiovascular disease (ASCVD). We performed a cross-sectional study to describe established ASCVD risk factors and estimate 10-year and lifetime risk of ASCVD in adults over age 18 with CHD of moderate or great complexity using 3 validated risk assessment tools-the Framingham Study Cardiovascular Disease Risk Assessment, the Reynolds Risk Score, and the ASCVD Risk Estimator. We obtained extensive clinical and survey data on 178 enrolled patients, with average age 37...
January 1, 2017: American Journal of Cardiology
label_collection
label_collection
3799
1
2
2017-12-31 00:27:02
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"