Mariona Jové, Gerard Mauri-Capdevila, Idalmis Suárez, Serafi Cambray, Jordi Sanahuja, Alejandro Quílez, Joan Farré, Ikram Benabdelhak, Reinald Pamplona, Manuel Portero-Otín, Francisco Purroy
OBJECTIVE: To discover, by using metabolomics, novel candidate biomarkers for stroke recurrence (SR) with a higher prediction power than present ones. METHODS: Metabolomic analysis was performed by liquid chromatography coupled to mass spectrometry in plasma samples from an initial cohort of 131 TIA patients recruited <24 hours after the onset of symptoms. Pattern analysis and metabolomic profiling, performed by multivariate statistics, disclosed specific SR and large-artery atherosclerosis (LAA) biomarkers...
January 6, 2015: Neurology