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35 papers 25 to 100 followers
By Oswaldo Vargas Health system pharmacist currently working on Medication Safety as a part of Patient Safety work task force group
https://www.readbyqxmd.com/read/27705091/guillain-barr%C3%A3-syndrome-associated-with-zika-virus-infection-in-colombia
#1
Beatriz Parra, Jairo Lizarazo, Jorge A Jiménez-Arango, Andrés F Zea-Vera, Guillermo González-Manrique, José Vargas, Jorge A Angarita, Gonzalo Zuñiga, Reydmar Lopez-Gonzalez, Cindy L Beltran, Karen H Rizcala, Maria T Morales, Oscar Pacheco, Martha L Ospina, Anupama Kumar, David R Cornblath, Laura S Muñoz, Lyda Osorio, Paula Barreras, Carlos A Pardo
Background Zika virus (ZIKV) infection has been linked to the Guillain-Barré syndrome. From November 2015 through March 2016, clusters of cases of the Guillain-Barré syndrome were observed during the outbreak of ZIKV infection in Colombia. We characterized the clinical features of cases of Guillain-Barré syndrome in the context of this ZIKV infection outbreak and investigated their relationship with ZIKV infection. Methods A total of 68 patients with the Guillain-Barré syndrome at six Colombian hospitals were evaluated clinically, and virologic studies were completed for 42 of the patients...
October 5, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27355913/role-of-diet-in-inflammatory-bowel-disease
#2
Frank M Ruemmele
The incidence of inflammatory bowel disease (IBD) is steadily in the rise in Western as well as in developing countries paralleling the increase of westernized diets, characterized by high protein and fat as well as excessive sugar intake, with less vegetables and fiber. An interesting hypothesis is that environmental (food-) triggered changes of the intestinal microbiome might cause a proinflammatory state preceding the development of IBD. Indeed, an intact intestinal epithelial barrier assuring a normal bacterial clearance of the intestinal surface is crucial to guarantee intestinal homeostasis...
2016: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/26919165/cardiotoxicity-of-anticancer-treatments-epidemiology-detection-and-management
#3
REVIEW
Giuseppe Curigliano, Daniela Cardinale, Susan Dent, Carmen Criscitiello, Olexiy Aseyev, Daniel Lenihan, Carlo Maria Cipolla
Answer questions and earn CME/CNE Cancer and heart disease are the leading causes of morbidity and mortality in the industrialized world. Modern treatment strategies have led to an improvement in the chances of surviving a diagnosis of cancer; however, these gains can come at a cost. Patients may experience adverse cardiovascular events related to their cancer treatment or as a result of an exacerbation of underlying cardiovascular disease. With longer periods of survival, late effects of cancer treatment may become clinically evident years or decades after completion of therapy...
July 2016: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/27213016/the-risk-of-intra-urethral-foley-catheter-balloon-inflation-in-spinal-cord-injured-patients-lessons-learned-from-a-retrospective-case-series
#4
Vaidyanathan Subramanian, Bakul M Soni, Peter L Hughes, Gurpreet Singh, Tun Oo
BACKGROUND: Inflating the balloon of Foley catheter in urethra is a complication of urethral catheterisation. We report five patients in whom this complication occurred because of unskilled catheterisation. Due to lack of awareness, the problem was not recognised promptly and patients came to harm. CASE SERIES: A tetraplegic patient developed pain in lower abdomen and became unwell after transurethral catheterisation. CT pelvis revealed full bladder with balloon of Foley catheter in dilated urethra...
2016: Patient Safety in Surgery
https://www.readbyqxmd.com/read/27568310/drug-therapy-management-in-patients-with-renal-impairment-how-to-use-creatinine-based-formulas-in-clinical-practice
#5
Willemijn L Eppenga, Cornelis Kramers, Hieronymus J Derijks, Michel Wensing, Jack F M Wetzels, Peter A G M De Smet
PURPOSE: The use of estimated glomerular filtration rate (eGFR) in daily clinical practice. METHODS: eGFR is a key component in drug therapy management (DTM) in patients with renal impairment. eGFR is routinely reported by laboratories whenever a serum creatinine testing is ordered. In this paper, we will discuss how to use eGFR knowing the limitations of serum creatinine-based formulas. RESULTS: Before starting a renally excreted drug, an equally effective drug which can be used more safely in patients with renal impairment should be considered...
December 2016: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27578562/oral-nifedipine-vs-intravenous-labetalol-for-treatment-of-pregnancy-induced-severe-pre-eclampsia
#6
D-D Shi, F-Z Yang, L Zhou, N Wang
WHAT IS KNOWN AND OBJECTIVE: Pre-eclampsia is one of the most challenging diseases of pregnancy. Both nifedipine and labetalol have been used for treatment of pregnancy-induced severe pre-eclampsia. METHODS: In the present study, the efficacy and safety of oral nifedipine and intravenous labetalol for severe pre-eclampsia therapy were compared. Eligible pregnant women with severe pre-eclampsia (n = 147) were allocated to receive either oral nifedipine or intravenous labetalol...
August 31, 2016: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/27578606/review-of-drug-utilization-patterns-in-nicus-worldwide
#7
N Krzyżaniak, I Pawłowska, B Bajorek
WHAT IS KNOWN AND OBJECTIVES: When considering acute care settings, such as the neonatal intensive care unit (NICU), the inappropriate use of medicines poses a great risk to vulnerable babies at the start of their lives. However, there is limited published literature that explores the current medication management practices in NICUs and where the main misuse issues lie. Therefore, the purpose of this review was to give an overview of medicine use in NICUs worldwide and identify therapeutic areas requiring more targeted pharmaceutical care...
August 31, 2016: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/27049966/united-kingdom-health-system-review
#8
Jonathan Cylus, Erica Richardson, Lisa Findley, Marcus Longley, Ciaran O'Neill, David Steel
This analysis of the United Kingdom health system reviews recent developments in organization and governance, health financing, health care provision, health reforms and health system performance. It provides an overview of how the national health services operate in the four nations that make up the United Kingdom, as responsibility for organizing health financing and services was devolved from 1997. With devolution, the health systems in the United Kingdom have diverged in the details of how services are organized and paid for, but all have maintained national health services which provide universal access to a comprehensive package of services that are mostly free at the point of use...
2015: Health Systems in Transition
https://www.readbyqxmd.com/read/26883737/associations-between-diabetes-self-management-and-microvascular-complications-in-patients-with-type-2-diabetes
#9
Fatemeh Mehravar, Mohammad Ali Mansournia, Kourosh Holakouie-Naieni, Ensie Nasli-Esfahani, Nasrin Mansournia, Amir Almasi-Hashiani
OBJECTIVES: Diabetes is a major public health problem that is approaching epidemic proportions globally. Diabetes self-management can reduce complications and mortality in type 2 diabetic patients. The purpose of this study was to examine associations between diabetes self-management and microvascular complications in patients with type 2 diabetes. METHODS: In this cross-sectional study, 562 Iranian patients older than 30 years of age with type 2 diabetes who received treatment at the Diabetes Research Center of the Endocrinology and Metabolism Research Institute of the Tehran University of Medical Sciences were identified...
2016: Epidemiology and Health
https://www.readbyqxmd.com/read/26775571/comparison-of-economic-evaluation-methods-across-low-income-middle-income-and-high-income-countries-what-are-the-differences-and-why
#10
COMPARATIVE STUDY
Ulla Kou Griffiths, Rosa Legood, Catherine Pitt
There are marked differences in methods used for undertaking economic evaluations across low-income, middle-income, and high-income countries. We outline the most apparent dissimilarities and reflect on their underlying reasons. We randomly sampled 50 studies from each of three country income groups from a comprehensive database of 2844 economic evaluations published between January 2012 and May 2014. Data were extracted on ten methodological areas: (i) availability of guidelines; (ii) research questions; (iii) perspective; (iv) cost data collection methods; (v) cost data analysis; (vi) outcome measures; (vii) modelling techniques; (viii) cost-effectiveness thresholds; (ix) uncertainty analysis; and (x) applicability...
February 2016: Health Economics
https://www.readbyqxmd.com/read/26745969/are-polyphenols-strong-dietary-agents-against-neurotoxicity-and-neurodegeneration
#11
Susana Almeida, Marco G Alves, Mário Sousa, Pedro F Oliveira, Branca M Silva
Life expectancy of most human populations has greatly increased as a result of factors including better hygiene, medical practice, and nutrition. Unfortunately, as humans age, they become more prone to suffer from neurodegenerative diseases and neurotoxicity. Polyphenols can be cheaply and easily obtained as part of a healthy diet. They present a wide range of biological activities, many of which have relevance for human health. Compelling evidence has shown that dietary phytochemicals, particularly polyphenols, have properties that may suppress neuroinflammation and prevent toxic and degenerative effects in the brain...
October 2016: Neurotoxicity Research
https://www.readbyqxmd.com/read/26715801/composing-effective-and-efficient-e-mails-a-primer-for-pharmacy-practitioners
#12
Marc R Summerfield, Agnes Ann Feemster
This primer describes the purpose and importance of e-mail as a key communication medium in the workplace. It emphasizes clarity as a primary modality to enhance efficiency and effectiveness. Finally, the primer reviews elements of grammar, punctuation, and style that contribute to each e-mail's ability to meet language standards, enhance the writer's image, and successfully transmit information.
September 2015: Hospital Pharmacy
https://www.readbyqxmd.com/read/26563876/breathing-exercises-for-adults-with-asthma
#13
(no author information available yet)
Asthma is a common long-term condition that remains poorly controlled in many people despite the availability of pharmacological interventions, evidence-based treatment guidelines and care pathways.(1) There is considerable public interest in the use of non-pharmacological approaches for the treatment of asthma.(2) A survey of people with asthma reported that many have used complementary and alternative medicine, often without the knowledge of their clinical team.(3) Such interventions include breathing techniques, herbal products, homeopathy and acupuncture...
November 2015: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/26560957/-novel-therapeutic-interventions-in-guillain-barr%C3%A3-syndrome-review-and-future-perspective
#14
REVIEW
Sonoko Misawa
Intravenous immunoglobulin (IVIg) and plasma exchange (PE) are of proven efficacy and are considered the standard therapy for Guillain Barré syndrome (GBS). However, some patients require artificial ventilation during the acute phase and experience long-lasting neurological deficits or symptoms. Currently, there is no established therapeutic intervention for GBS other than IVIg and PE, even though a number of compounds have been investigated. Clinical trials to investigate the efficacy and safety of a second IVIg or eculizumab are ongoing...
November 2015: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/26266465/pharmaceutical-role-expansion-and-developments-in-pharmacist-physician-communication
#15
Alicia A Bergman, Heather A Jaynes, Jasmine D Gonzalvo, Karen Suchanek Hudmon, Richard M Frankel, Amanda L Kobylinski, Alan J Zillich
Expanded clinical pharmacist professional roles in the team-based patient-centered medical home (PCMH) primary care environment require cooperative and collaborative relationships among pharmacists and primary care physicians (PCPs), but many PCPs have not previously worked in such a direct fashion with pharmacists. Additional roles, including formulary control, add further elements of complexity to the clinical pharmacist-PCP relationship that are not well described. Our objective was to characterize the nature of clinical pharmacist-PCP interprofessional collaboration across seven federally funded hospitals and associated primary care clinics, following pharmacist placement in primary care clinics and incorporation of expanded pharmacist roles...
2016: Health Communication
https://www.readbyqxmd.com/read/26344010/surgical-site-infection-following-cesarean-delivery-patient-provider-and-procedure-specific-risk-factors
#16
Raj Shree, Seo Young Park, Richard H Beigi, Shannon L Dunn, Elizabeth E Krans
OBJECTIVE: This study aims to identify risk factors for cesarean delivery (CD) surgical site infection (SSI). study design: Retrospective analysis of 2,739 CDs performed at the University of Pittsburgh in 2011. CD SSIs were defined using National Healthcare Safety Network (NHSN) criteria. Chi-square test and t-test were used for bivariate analyses and multivariate logistic regression was used to identify SSI risk factors. RESULTS: Of 2,739 CDs, 178 (6.5%) were complicated by SSI...
January 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/26337510/supporting-pharmacists-in-general-practice
#17
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
September 2015: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/25820169/intravenous-imaging-contrast-media-complications-the-basics-that-every-clinician-needs-to-know
#18
REVIEW
Trevor A Rose, Jung W Choi
Intravenous contrast is commonly used in noninvasive imaging procedures such as magnetic resonance imaging and computed tomography and can evaluate blood vessels and better characterize soft-tissue lesions. Although the incidence of adverse events after administration of contrast is low, it is important that clinicians and radiologists minimize risks and respond quickly and effectively when reactions occur. We will discuss a range of adverse events to iodinated and gadolinium-based contrast agents, including allergic-like reactions, nephrotoxicity, extravasation, and nephrogenic systemic fibrosis...
September 2015: American Journal of Medicine
https://www.readbyqxmd.com/read/26150573/ashp-guidelines-minimum-standard-for-ambulatory-care-pharmacy-practice
#19
REVIEW
Jennifer Askew Buxton, RoseMarie Babbitt, Cyndy A Clegg, Sandra F Durley, Kelly T Epplen, Laurel M Marsden, Bridgette A Thomas, Nathan S Thompson
No abstract text is available yet for this article.
July 15, 2015: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/26089046/patient-safety-in-procedural-dermatology-part-ii-safety-related-to-cosmetic-procedures
#20
REVIEW
Margarita Lolis, Scott W Dunbar, David J Goldberg, Timothy J Hansen, Deborah F MacFarlane
Cosmetic procedures are growing in popularity and are associated with unique risks. Considering potential complications and prioritizing patient safety will help practitioners improve outcomes of elective procedures. In part II of this continuing medical education article, we provide a comprehensive review of patient safety in cosmetic procedures, including medical and legal issues surrounding the supervision and training of physician extenders.
July 2015: Journal of the American Academy of Dermatology
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