Hideki Fujii, Keiji Kono, Kentaro Nakai, Shunsuke Goto, Riko Kitazawa, Masafumi Fukagawa, Shinichi Nishi
BACKGROUND/AIMS: The purpose of our study was to elucidate the relationship between asymmetric dimethylarginine (ADMA) and intrarenal lesions and to determine the effect of renin-angiotensin system inhibitors (RAS-Is) on serum ADMA levels, nitric oxide (NO) synthesis and oxidative stress in normotensive patients with chronic kidney disease (CKD). METHODS: This study included 23 normotensive patients with chronic glomerulonephritis and normal or mildly impaired renal function who underwent renal biopsy...
January 2014: Nephron Extra