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B12 Pathophysiology elevated

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1 papers 0 to 25 followers B12
By Susan Portis Ferguson MD Family physician. Universe sends her a lot of disorders in autoimmune, mitochondrial, neuroendocrine, MTHFR & headache categories.
https://www.readbyqxmd.com/read/23447660/the-pathophysiology-of-elevated-vitamin-b12-in-clinical-practice
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E Andrès, K Serraj, J Zhu, A J M Vermorken
Hypercobalaminemia (high serum vitamin B12 levels) is a frequent and underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, reflecting a functional deficiency linked to qualitative abnormalities, which are related to defects in tissue uptake and action of vitamin B12. The aetiological profile of high serum cobalamin predominantly encompasses severe disease entities for which early diagnosis is critical for prognosis. These entities are essentially comprised of solid neoplasms, haematological malignancies and liver and kidney diseases...
June 2013: QJM: Monthly Journal of the Association of Physicians
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