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https://www.readbyqxmd.com/read/15888698/radical-prostatectomy-versus-watchful-waiting-in-early-prostate-cancer
#1
RANDOMIZED CONTROLLED TRIAL
Anna Bill-Axelson, Lars Holmberg, Mirja Ruutu, Michael Häggman, Swen-Olof Andersson, Stefan Bratell, Anders Spångberg, Christer Busch, Stig Nordling, Hans Garmo, Juni Palmgren, Hans-Olov Adami, Bo Johan Norlén, Jan-Erik Johansson
BACKGROUND: In 2002, we reported the initial results of a trial comparing radical prostatectomy with watchful waiting in the management of early prostate cancer. After three more years of follow-up, we report estimated 10-year results. METHODS: From October 1989 through February 1999, 695 men with early prostate cancer (mean age, 64.7 years) were randomly assigned to radical prostatectomy (347 men) or watchful waiting (348 men). The follow-up was complete through 2003, with blinded evaluation of the causes of death...
May 12, 2005: New England Journal of Medicine
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