Read by QxMD icon Read

Decision analysis

shared collection
84 papers 0 to 25 followers
By Jamie Jarmul Md / PhD student at UNC - Chapel Hill, PhD in Health Policy and Management
Douglas K Owens, Evelyn P Whitlock, Jillian Henderson, Michael P Pignone, Alex H Krist, Kirsten Bibbins-Domingo, Susan J Curry, Karina W Davidson, Mark Ebell, Matthew W Gillman, David C Grossman, Alex R Kemper, Ann E Kurth, Michael Maciosek, Albert L Siu, Michael L LeFevre
The U.S. Preventive Services Task Force (USPSTF) develops evidence-based recommendations about preventive care based on comprehensive systematic reviews of the best available evidence. Decision models provide a complementary, quantitative approach to support the USPSTF as it deliberates about the evidence and develops recommendations for clinical and policy use. This article describes the rationale for using modeling, an approach to selecting topics for modeling, and how modeling may inform recommendations about clinical preventive services...
October 4, 2016: Annals of Internal Medicine
Kaleb Michaud, Vibeke Strand, Nancy A Shadick, Irina Degtiar, Kerri Ford, Steven N Michalopoulos, John Hornberger
OBJECTIVE: The multibiomarker disease activity (MBDA) blood test has been clinically validated as a measure of disease activity in patients with RA. We aimed to estimate the effect of the MBDA test on physical function for patients with RA (based on HAQ), quality-adjusted life years and costs over 10 years. METHODS: A decision analysis was conducted to quantify the effect of using the MBDA test on RA-related outcomes and costs to private payers and employers. Results of a clinical management study reporting changes to anti-rheumatic drug recommendations after use of the MBDA test informed clinical utility...
September 2015: Rheumatology
Brian Custer, Mart P Janssen
Analytical methods appropriate for health economic assessments of transfusion safety interventions have not previously been described in ways that facilitate their use. Within the context of risk-based decision-making (RBDM), health economics can be important for optimizing decisions among competing interventions. The objective of this review is to address key considerations and limitations of current methods as they apply to blood safety. Because a voluntary blood supply is an example of a public good, analyses should be conducted from the societal perspective when possible...
August 2015: Transfusion
Deborah J Lightner
No abstract text is available yet for this article.
May 1, 2015: International Journal of Cardiology
Jennifer Mason Lobo, Adam P Dicker, Christine Buerki, Elai Daviconi, R Jeffrey Karnes, Robert B Jenkins, Nirav Patel, Robert B Den, Timothy N Showalter
BACKGROUND: Currently there is controversy surrounding the optimal way to treat patients with prostate cancer in the post-prostatectomy setting. Adjuvant therapies carry possible benefits of improved curative results, but there is uncertainty in which patients should receive adjuvant therapy. There are concerns about giving toxicity to a whole population for the benefit of only a subset. We hypothesized that making post-prostatectomy treatment decisions using genomics-based risk prediction estimates would improve cancer and quality of life outcomes...
2015: PloS One
Jeffrey D Stone, Lisa M Vaccaro, R Colin Brabender, Alfred V Hess
PURPOSE: To evaluate the utility of radiographs taken 2 weeks following plate fixation of distal radius fractures. METHODS: A retrospective review of patients requiring operative fixation of distal radius fractures was performed with the objective of determining the utility of a 2-week postoperative radiograph in patient management. RESULTS: Three out of 268 (1%) patients had loss of fixation noted radiographically at the 2-week visit that resulted in a reoperation...
June 2015: Journal of Hand Surgery
JoAnn Mick
This column shares the best evidence-based strategies and innovative ideas on how to facilitate the learning of EBP principles and processes by clinicians as well as nursing and interprofessional students. Guidelines for submission are available at
June 2015: Worldviews on Evidence-based Nursing
Kelly Yamasato, Bliss Kaneshiro, Jennifer Salcedo
AIM: Neuraxial blockade (epidural or spinal anesthesia/analgesia) with external cephalic version increases the external cephalic version success rate. Hospitals and insurers may affect access to neuraxial blockade for external cephalic version, but the costs to these institutions remain largely unstudied. The objective of this study was to perform a cost analysis of neuraxial blockade use during external cephalic version from hospital and insurance payer perspectives. Secondarily, we estimated the effect of neuraxial blockade on cesarean delivery rates...
July 2015: Journal of Obstetrics and Gynaecology Research
Mehdi Najafzadeh, Sebastian Schneeweiss, Niteesh Choudhry, Katsiaryna Bykov, Kristijan H Kahler, Diane P Martin, Joshua J Gagne
BACKGROUND: Patients, physicians, and other decision makers make implicit but inevitable trade-offs among risks and benefits of treatments. Many methods have been proposed to promote transparent and rigorous benefit-risk analysis (BRA). OBJECTIVE: To propose a framework for classifying BRA methods on the basis of key factors that matter most for patients by using a common mathematical notation and compare their results using a hypothetical example. METHODS: We classified the available BRA methods into three categories: 1) unweighted metrics, which use only probabilities of benefits and risks; 2) metrics that incorporate preference weights and that account for the impact and duration of benefits and risks; and 3) metrics that incorporate weights based on decision makers' opinions...
March 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Zoltán Kaló, Anke-Peggy Holtorf, Rafael Alfonso-Cristancho, Jie Shen, Tamás Ágh, András Inotai, Diana Brixner
Policymakers tend to focus on improving patented drug policies because they are under pressure from patients, physicians, and manufacturers to increase access to novel therapies. The success of pharmaceutical innovation over the last few decades has led to the availability of many off-patent drugs to treat disease areas with the greatest public health need. Therefore, the success of public health programs in improving the health status of the total population is highly dependent on the efficiency of generic drug policies...
March 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Catherine Juillard, Randi Smith, Nancy Anaya, Arturo Garcia, James G Kahn, Rochelle A Dicker
BACKGROUND: Victims of violence are at significant risk for injury recidivism, including fatality. We previously demonstrated that our hospital-based violence intervention program (VIP) resulted in a fourfold reduction in injury recidivism, avoiding trauma care costs of $41,000 per injury. Given limited trauma center resources, assessing cost-effectiveness of interventions is fundamental to inform use of these programs in other institutions. This study examines the cost-effectiveness of hospital-based VIP...
February 2015: Journal of Trauma and Acute Care Surgery
Carlos E Rodríguez-Martínez, Monica P Sossa-Briceño, Elkin Vladimir Lemos
INTRODUCTION: Allergic rhinitis (AR) is one of the most common chronic respiratory diseases observed in the pediatric population, producing a significant morbidity, and an economic burden due to direct medical costs and indirect costs. Despite the high prevalence of AR in children and the importance of the use of topical intranasal corticosteroids for its treatment, comparative analyses of alternative treatments in pediatric patients, in terms of both cost and effectiveness are lacking...
March 2015: Advances in Therapy
Hassan M Ghomrawi, Ashley A Eggman, Andrew D Pearle
BACKGROUND: Trade-offs between upfront benefits and later risk of revision of unicompartmental knee arthroplasty compared with those of total knee arthroplasty are poorly understood. The purpose of our study was to compare the cost-effectiveness of unicompartmental knee arthroplasty with that of total knee arthroplasty across the age spectrum of patients undergoing knee replacement. METHODS: Using a Markov decision analytic model, we compared unicompartmental knee arthroplasty with total knee arthroplasty with regard to lifetime costs, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs) from a societal perspective for patients undergoing surgery at forty-five, fifty-five, sixty-five, seventy-five, or eighty-five years of age...
March 4, 2015: Journal of Bone and Joint Surgery. American Volume
Bernice Tsoi, Ron Goeree, Jathishinie Jegathisawaran, Jean-Eric Tarride, Gord Blackhouse, Daria O'Reilly
When choosing a modeling approach for health economic evaluation, certain criteria are often considered (e.g., population resolution, interactivity, time advancement mechanism, resource constraints). However, whether these criteria and their associated modeling approach impacts results remain poorly understood. A systematic review was conducted to identify cross-validation studies (i.e., modeling a problem using different approaches with the same body of evidence) to offer insight on this topic. With respect to population resolution, reviewed studies suggested that both aggregate- and individual-level models will generate comparable results, although a practical trade-off exists between validity and feasibility...
June 2015: Expert Review of Pharmacoeconomics & Outcomes Research
Huseyin Naci, Gert van Valkenhoef, Julian P T Higgins, Rachael Fleurence, A E Ades
No abstract text is available yet for this article.
September 2014: Circulation. Cardiovascular Quality and Outcomes
Mark H Eckman, Ruth E Wise, Barbara Speer, Megan Sullivan, Nita Walker, Gregory Y H Lip, Brett Kissela, Matthew L Flaherty, Dawn Kleindorfer, Faisal Khan, John Kues, Peter Baker, Robert Ireton, Dave Hoskins, Brett M Harnett, Carlos Aguilar, Anthony Leonard, Rajan Prakash, Lora Arduser, Alexandru Costea
BACKGROUND: Guidelines for anticoagulant therapy in patients with atrial fibrillation are based on stroke risk as calculated by either the CHADS2 or the CHA2DS2VASc scores and do not integrate bleeding risk in an explicit, quantitative manner. Our objective was to quantify the net clinical benefit resulting from improved decision making about antithrombotic therapy. METHODS AND RESULTS: This study is a retrospective cohort study of 1876 adults with nonvalvular atrial fibrillation or flutter seen in primary care settings of an integrated healthcare delivery system between December 2012 and January 2014...
September 2014: Circulation. Cardiovascular Quality and Outcomes
Joyce H S You, Wai-Kit Ming, Paul K S Chan
Trivalent influenza vaccine (TIV) selects one of the 2 co-circulating influenza B lineages whereas quadrivalent influenza vaccine (QIV) includes both lineages. We examined potential cost-effectiveness of QIV versus TIV from perspectives of healthcare provider and society of Hong Kong. A decision tree was designed to simulate the outcomes of QIV vs. TIV in 6 age groups: 0-4 years, 5-9 years, 10-14 years, 15-64 years, 65-79 y and ≥80 years. Direct cost alone, direct and indirect costs, and quality-adjusted life-years (QALYs) loss due to TIV-unmatched influenza B infection were simulated for each study arm...
2015: Human Vaccines & Immunotherapeutics
Francois Dionne, Craig Mitton, Bill Dempster, Larry D Lynd
BACKGROUND: Coverage decisions for a new drug revolve around the balance between perceived value and price. But what is the perceived value of a new drug? Traditionally, the assessment of such value has largely revolved around the estimation of cost-effectiveness. However, very few will argue that the cost-effectiveness ratio presents a fulsome picture of 'value'. Multi-criteria decision analysis (MCDA) has been advocated as an alternative to cost-effectiveness analysis and it has been argued that it better reflects real world decision-making...
2015: Journal of Population Therapeutics and Clinical Pharmacology
Clifton Meals, Meredith Osterman
PURPOSE: To investigate expectations, logistics, and costs relevant to the hand surgery fellowship application process. We sought to discover (1) what both applicants and program directors are seeking, (2) what both parties have to offer, (3) how both parties collect information about each other, and (4) the costs incurred in arranging each match. METHODS: We conducted on-line surveys of hand surgery fellowship applicants for appointment in 2015 and of current fellowship program directors...
April 2015: Journal of Hand Surgery
Benjamin J Shore, Daniel J Hedequist, Patricia E Miller, Peter M Waters, Donald S Bae
PURPOSE: The purpose of this investigation was to determine which of the following methods of fixation, percutaneous pinning (PP) or intramedullary nailing (IMN), was more cost-effective in the treatment of displaced pediatric proximal humeral fractures (PPHF). METHODS: A retrospective cohort of surgically treated PPHF over a 12-year period at a single institution was performed. A decision analysis model was constructed to compare three surgical strategies: IMN versus percutaneous pinning leaving the pins exposed (PPE) versus leaving the pins buried (PPB)...
February 2015: Journal of Children's Orthopaedics
2015-02-26 06:12:56
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"