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Pediatrics

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429 papers 500 to 1000 followers Articles to know about/Full Review Articles - Downloadable Full Articles
https://www.readbyqxmd.com/read/28120042/recent-advances-in-epilepsy
#1
Mark Manford
This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy's broader comorbidity, especially depression...
January 24, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28183838/autoimmune-encephalitis-pathophysiology-and-imaging-review-of-an-overlooked-diagnosis
#2
REVIEW
B P Kelley, S C Patel, H L Marin, J J Corrigan, P D Mitsias, B Griffith
Autoimmune encephalitis is a relatively new category of immune-mediated disease involving the central nervous system that demonstrates a widely variable spectrum of clinical presentations, ranging from the relatively mild or insidious onset of cognitive impairment to more complex forms of encephalopathy with refractory seizure. Due to its diverse clinical features, which can mimic a variety of other pathologic processes, autoimmune encephalitis presents a diagnostic challenge to clinicians. Imaging findings in patients with these disorders can also be quite variable, but recognizing characteristic findings within limbic structures suggestive of autoimmune encephalitis can be a key step in alerting clinicians to the potential diagnosis and ensuring a prompt and appropriate clinical work-up...
February 9, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28276062/ilae-classification-of-the-epilepsies-position-paper-of-the-ilae-commission-for-classification-and-terminology
#3
Ingrid E Scheffer, Samuel Berkovic, Giuseppe Capovilla, Mary B Connolly, Jacqueline French, Laura Guilhoto, Edouard Hirsch, Satish Jain, Gary W Mathern, Solomon L Moshé, Douglas R Nordli, Emilio Perucca, Torbjörn Tomson, Samuel Wiebe, Yue-Hua Zhang, Sameer M Zuberi
The International League Against Epilepsy (ILAE) Classification of the Epilepsies has been updated to reflect our gain in understanding of the epilepsies and their underlying mechanisms following the major scientific advances that have taken place since the last ratified classification in 1989. As a critical tool for the practicing clinician, epilepsy classification must be relevant and dynamic to changes in thinking, yet robust and translatable to all areas of the globe. Its primary purpose is for diagnosis of patients, but it is also critical for epilepsy research, development of antiepileptic therapies, and communication around the world...
April 2017: Epilepsia
https://www.readbyqxmd.com/read/27979889/2-classification-and-diagnosis-of-diabetes
#4
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Diabetes Care
https://www.readbyqxmd.com/read/27754180/ed-08-4-diagnosis-and-treatment-of-hypertensive-emergency-in-children
#5
Lin Shi
According to the seventh report of Joint National Committee (JNC 7), hypertensive emergency (HE), a kind of hypertensive crisis, is defined as a sudden and abrupt elevation in blood pressure so as to cause acute target organ dysfunctions, including central nervous system, cardiovascular system or kidneys. Patients with HE require immediate reduction in markedly elevated blood pressure. Currently, there are no international guidelines for children HE, so the JNC definition is commonly used. Hypertensive emergency in children is rare but a life-threatening emergency...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27604932/how-to-raise-a-genius-lessons-from-a-45-year-study-of-super-smart-children
#6
Tom Clynes
No abstract text is available yet for this article.
September 8, 2016: Nature
https://www.readbyqxmd.com/read/27349388/pfapa-syndrome-a-review-on-treatment-and-outcome
#7
REVIEW
Federica Vanoni, Katerina Theodoropoulou, Michaël Hofer
The syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA syndrome) is the most common cause of periodic fever in childhood. The current pharmacological treatment includes corticosteroids, which usually are efficacious in the management of fever episodes, colchicine, for the prophylaxis of febrile episodes, and other medication for which efficacy has not been proven so far. Tonsillectomy is an option for selected patients. Usually PFAPA syndrome resolves during adolescence, but there is increasing evidence that this condition may persist into adulthood...
June 27, 2016: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/26289061/recent-advances-in-paediatric-respiratory-medicine
#8
REVIEW
Andrew Turnbull, Ian M Balfour-Lynn
This review highlights important advances in paediatric respiratory medicine since 2014, excluding cystic fibrosis. It focuses mainly on the more common conditions, bronchopulmonary dysplasia, bronchiolitis and preschool wheezing, asthma, pneumonia and sleep, and highlights some of the rarer conditions such as primary ciliary dyskinesia and interstitial lung disease (ILD).
February 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27252178/cytomegalovirus-and-epstein-barr-virus-infections
#9
REVIEW
Swetha Pinninti, Catherine Hough-Telford, Sunil Pati, Suresh Boppana
No abstract text is available yet for this article.
June 2016: Pediatrics in Review
https://www.readbyqxmd.com/read/27287728/the-didactic-makeover-keep-it-short-active-relevant
#10
REVIEW
Molly Rideout, Melissa Held, Alison Volpe Holmes
No abstract text is available yet for this article.
July 2016: Pediatrics
https://www.readbyqxmd.com/read/27139328/pediatric-sedation-management
#11
REVIEW
Sean Barnes, Myron Yaster, Sapna R Kudchadkar
No abstract text is available yet for this article.
May 2016: Pediatrics in Review
https://www.readbyqxmd.com/read/26749112/pediatric-nonalcoholic-fatty-liver-disease-a-report-from-the-expert-committee-on%C3%A2-nonalcoholic-fatty-liver%C3%A2-disease-econ
#12
Rohit Kohli, Shikha Sunduram, Marialena Mouzaki, Sabina Ali, Pushpa Sathya, Stephanie Abrams, Stavra A Xanthakos, Miriam Vos, Jeffrey B Schwimmer
No abstract text is available yet for this article.
May 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27154366/targeted-treatment-in-childhood-epilepsy-syndromes
#13
REVIEW
Katharina Vezyroglou, J Helen Cross
The mainstay of treatment of epilepsy has been antiepileptic drugs; however, despite the emergence of new agents, a consistent proportion remain drug-resistant. Newer AEDs show promise. However, as it becomes clear that the epilepsies are a group of diseases rather than a single disorder the prospect of targeted treatment in some may become a reality.
June 2016: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/27083888/vestibular-migraine-the-most-frequent-entity-of-episodic-vertigo
#14
REVIEW
Marianne Dieterich, Mark Obermann, Nese Celebisoy
Vestibular migraine (VM) is the most common cause of episodic vertigo in adults as well as in children. The diagnostic criteria of the consensus document of the International Bárány Society for Neuro-Otology and the International Headache Society (2012) combine the typical signs and symptoms of migraine with the vestibular symptoms lasting 5 min to 72 h and exclusion criteria. Although VM accounts for 7% of patients seen in dizziness clinics and 9% of patients seen in headache clinics it is still underdiagnosed...
April 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27059727/prevention-of-food-allergy
#15
REVIEW
George du Toit, Teresa Tsakok, Simon Lack, Gideon Lack
The past few decades have witnessed an increase in the prevalence of IgE-mediated food allergy (FA). For prevention strategies to be effective, we need to understand the causative factors underpinning this rise. Genetic factors are clearly important in the development of FA, but given the dramatic increase in prevalence over a short period of human evolution, it is unlikely that FA arises through germline genetic changes alone. A plausible hypothesis is that 1 or more environmental exposures, or lack thereof, induce epigenetic changes that result in interruption of the default immunologic state of tolerance...
April 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/26534956/pediatric-pulmonary-hypertension-guidelines-from-the-american-heart-association-and-american-thoracic-society
#16
Steven H Abman, Georg Hansmann, Stephen L Archer, D Dunbar Ivy, Ian Adatia, Wendy K Chung, Brian D Hanna, Erika B Rosenzweig, J Usha Raj, David Cornfield, Kurt R Stenmark, Robin Steinhorn, Bernard Thébaud, Jeffrey R Fineman, Titus Kuehne, Jeffrey A Feinstein, Mark K Friedberg, Michael Earing, Robyn J Barst, Roberta L Keller, John P Kinsella, Mary Mullen, Robin Deterding, Thomas Kulik, George Mallory, Tilman Humpl, David L Wessel
Pulmonary hypertension is associated with diverse cardiac, pulmonary, and systemic diseases in neonates, infants, and older children and contributes to significant morbidity and mortality. However, current approaches to caring for pediatric patients with pulmonary hypertension have been limited by the lack of consensus guidelines from experts in the field. In a joint effort from the American Heart Association and American Thoracic Society, a panel of experienced clinicians and clinician-scientists was assembled to review the current literature and to make recommendations on the diagnosis, evaluation, and treatment of pediatric pulmonary hypertension...
November 24, 2015: Circulation
https://www.readbyqxmd.com/read/27062475/hospital-management-of-paediatric-functional-somatic-symptoms
#17
EDITORIAL
M Elena Garralda
No abstract text is available yet for this article.
May 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/26819490/clinical-applications-of-hemolytic-markers-in-the-differential-diagnosis-and-management-of-hemolytic-anemia
#18
REVIEW
W Barcellini, B Fattizzo
Several hemolytic markers are available to guide the differential diagnosis and to monitor treatment of hemolytic conditions. They include increased reticulocytes, an indicator of marrow compensatory response, elevated lactate dehydrogenase, a marker of intravascular hemolysis, reduced haptoglobin, and unconjugated hyperbilirubinemia. The direct antiglobulin test is the cornerstone of autoimmune forms, and blood smear examination is fundamental in the diagnosis of congenital membrane defects and thrombotic microangiopathies...
2015: Disease Markers
https://www.readbyqxmd.com/read/26942447/the-definition-of-ards-revisited-20%C3%A2-years-later
#19
EDITORIAL
Gordon R Bernard, Antonio Artigas
No abstract text is available yet for this article.
May 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/26977974/what-is-ecmo
#20
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
March 15, 2016: American Journal of Respiratory and Critical Care Medicine
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