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Antiagregacion-Anticoagulacion

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4 papers 0 to 25 followers
By M. Carmen Martinez Velasco Internal Medicine
https://www.readbyqxmd.com/read/25939012/in-the-clinic-deep-venous-thrombosis
#1
REVIEW
John Spandorfer, Taki Galanis
This issue provides a clinical overview of deep venous thrombosis, focusing on prevention, diagnosis, treatment, and patient information. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including ACP Smart Medicine and MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic from these primary sources in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of science writers and physician writers...
May 5, 2015: Annals of Internal Medicine
https://www.readbyqxmd.com/read/25512338/the-risks-of-thromboembolism-vs-recurrent-gastrointestinal-bleeding-after-interruption-of-systemic-anticoagulation-in-hospitalized-inpatients-with-gastrointestinal-bleeding-a-prospective-study
#2
N Sengupta, J D Feuerstein, V R Patwardhan, E B Tapper, G A Ketwaroo, A M Thaker, D A Leffler
OBJECTIVES: Anticoagulants carry a significant risk of gastrointestinal bleeding (GIB). Data regarding the safety of anticoagulation continuation/cessation after GIB are limited. We sought to determine the safety and risk of continuation of anticoagulation after GIB. METHODS: We conducted a prospective observational cohort study on consecutive patients admitted to the hospital who had GIB while on systemic anticoagulation. Patients were classified into two groups at hospital discharge after GIB: those who resumed anticoagulation and those who had anticoagulation discontinued...
February 2015: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/25262258/reasons-for-warfarin-discontinuation-in-the-outcomes-registry-for-better-informed-treatment-of-atrial-fibrillation-orbit-af
#3
MULTICENTER STUDY
Emily C O'Brien, DaJuanicia N Simon, Larry A Allen, Daniel E Singer, Gregg C Fonarow, Peter R Kowey, Laine E Thomas, Michael D Ezekowitz, Kenneth W Mahaffey, Paul Chang, Jonathan P Piccini, Eric D Peterson
BACKGROUND: Warfarin reduces thromboembolic risks in atrial fibrillation (AF), but therapeutic durability remains a concern. METHODS: We used clinical data from ORBIT-AF, a nationwide outpatient AF registry conducted at 176 sites with follow-up data at 6 and 12 months, to examine longitudinal patterns of warfarin discontinuation. We estimated associations between patient and provider characteristics and report of any warfarin discontinuation using discrete time proportional odds models...
October 2014: American Heart Journal
https://www.readbyqxmd.com/read/23803136/clopidogrel-with-aspirin-in-acute-minor-stroke-or-transient-ischemic-attack
#4
RANDOMIZED CONTROLLED TRIAL
Yongjun Wang, Yilong Wang, Xingquan Zhao, Liping Liu, David Wang, Chunxue Wang, Chen Wang, Hao Li, Xia Meng, Liying Cui, Jianping Jia, Qiang Dong, Anding Xu, Jinsheng Zeng, Yansheng Li, Zhimin Wang, Haiqin Xia, S Claiborne Johnston
BACKGROUND: Stroke is common during the first few weeks after a transient ischemic attack (TIA) or minor ischemic stroke. Combination therapy with clopidogrel and aspirin may provide greater protection against subsequent stroke than aspirin alone. METHODS: In a randomized, double-blind, placebo-controlled trial conducted at 114 centers in China, we randomly assigned 5170 patients within 24 hours after the onset of minor ischemic stroke or high-risk TIA to combination therapy with clopidogrel and aspirin (clopidogrel at an initial dose of 300 mg, followed by 75 mg per day for 90 days, plus aspirin at a dose of 75 mg per day for the first 21 days) or to placebo plus aspirin (75 mg per day for 90 days)...
July 4, 2013: New England Journal of Medicine
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