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Lung cancer

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https://www.readbyqxmd.com/read/24922462/effectiveness-of-the-buccal-mucosa-route-for-methadone-administration-at-the-end-of-life
#1
Donna Spaner
BACKGROUND: Methadone is a useful analgesic for neuropathic and nociceptive pain. However, there is little information about the use of methadone in the final days of life when a patient cannot swallow, discouraging its use by many palliative care physicians. OBJECTIVE: The purpose of this study was to investigate the effectiveness of switching patients on oral methadone at the end of life to methadone by the buccal mucosa route. METHODS: This is a case series comprising 36 patients on the Toronto Grace Palliative Care Unit (PCU) who took methadone between 2010 and 2012...
November 2014: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/20818875/early-palliative-care-for-patients-with-metastatic-non-small-cell-lung-cancer
#2
RANDOMIZED CONTROLLED TRIAL
Jennifer S Temel, Joseph A Greer, Alona Muzikansky, Emily R Gallagher, Sonal Admane, Vicki A Jackson, Constance M Dahlin, Craig D Blinderman, Juliet Jacobsen, William F Pirl, J Andrew Billings, Thomas J Lynch
BACKGROUND: Patients with metastatic non-small-cell lung cancer have a substantial symptom burden and may receive aggressive care at the end of life. We examined the effect of introducing palliative care early after diagnosis on patient-reported outcomes and end-of-life care among ambulatory patients with newly diagnosed disease. METHODS: We randomly assigned patients with newly diagnosed metastatic non-small-cell lung cancer to receive either early palliative care integrated with standard oncologic care or standard oncologic care alone...
August 19, 2010: New England Journal of Medicine
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