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Via biliar y páncreas

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132 papers 25 to 100 followers
By Alejandro Peñarrieta Daher Residente de Cirugía Pediatrica en Hospital Infantil de México Federico Gómez
Steven M Strasberg, L Michael Brunt
No abstract text is available yet for this article.
October 14, 2016: Annals of Surgery
Max Bolun Liu, Thuy Bui Huong, Xuyen Hoang, Lan Doan, Shauna Trinh, Hoa Pham Anh Nguyen, Hai Thanh Le, Ai-Xuan Holterman
BACKGROUND: Biliary atresia is an idiopathic, neonatal liver disease of the bile ducts. The natural evolution of biliary atresia is known in developed countries. This study describes the clinical course of biliary atresia in Vietnam, a developing country. METHODS: Chart reviews were undertaken of patients treated with or without the Kasai procedure between January 2010 and July 2013 at a children's hospital in Vietnam. RESULTS: Of 287 children with biliary atresia, 149 (52%) were treated without the Kasai procedure and 138 (48%) were treated with the Kasai procedure...
October 12, 2016: Surgery
Zhen Shen, Shan Zheng, Rui Dong, Gong Chen
PURPOSE: We aimed to study whether saturation in HSV color model could be a parameter for acholic stool and utilized for designing a mobile application for screening biliary atresia (BA). METHODS: Saturations of the colors in the three validated stool color cards (Taiwan, Japan, Britain) were read using PHOTOSHOP. Stools from 40 BA patients and 40 in-hospital neonates with pneumonia were photographed and analyzed with color-analyzing mobile applications. RESULTS: Saturations of normal colors in the published stool cards were all >50% (67%~99%, median 85%) and were all <50% (7~47%, median 25%) for abnormal colors...
September 16, 2016: Journal of Pediatric Surgery
Masaki Nio, Motoshi Wada, Hideyuki Sasaki, Takuro Kazama, Hiromu Tanaka, Hironori Kudo
BACKGROUND: The purpose of this study was to assess the clinical outcome of patients treated with the current technique of Kasai procedure compared with that of those treated with previous procedures. METHODS: We retrospectively assessed the outcomes of 256 patients with biliary atresia who underwent Kasai portoenterostomy at our hospital between 1972 and 2014. Patients were divided into four groups: group 1 (1972-1981, double Roux-en Y, n=91), group 2 (1982-1991, Suruga II, n=80), group 3 (1992-2000, double-valve Roux-en Y, n=46), and group 4 (2001-2014, total removal of the extrahepatic biliary remnants at hepatic capsule and Roux-en Y reconstruction with a spur valve, n=39)...
September 16, 2016: Journal of Pediatric Surgery
Augusto Zani, Mark Davenport
INTRODUCTION: Infants with biliary atresia (BA) develop a degree of hepatic fibrosis as a consequence of their cholangiopathy. Some of them present clinically evident ascites that might predispose to inguinal hernias. We aimed to investigate whether infants with BA have a higher incidence of inguinal hernias. METHODS: Single-center retrospective review of all BA infants diagnosed between January 2006 and December 2010. Infants with a clinical diagnosis of inguinal hernia were identified and compared with those without...
April 2012: European Journal of Pediatric Surgery
Michael W Wandling, Eric S Hungness, Emily S Pavey, Jonah J Stulberg, Ben Schwab, Anthony D Yang, Michael B Shapiro, Karl Y Bilimoria, Clifford Y Ko, Avery B Nathens
Importance: There are currently 2 widely accepted treatment strategies for patients presenting to the hospital with choledocholithiasis. However, the rate of use for each strategy in the United States has not been evaluated, and their trends over time have not been described. Furthermore, an optimal management strategy for choledocholithiasis has yet to be defined. Objective: To evaluate secular trends in the management of choledocholithiasis in the United States and to compare hospital length of stay between patients with choledocholithiasis treated with endoscopic retrograde cholangiopancreatography with laparoscopic cholecystectomy (ERCP+LC) vs laparoscopic common bile duct exploration with laparoscopic cholecystectomy (LCBDE+LC)...
August 24, 2016: JAMA Surgery
Kensuke Yokoyama, Hisashi Hatanaka, Mikihiro Inoue, Tomonori Yano, Norikatsu Numao, Jun Ushio, Alan Kawarai Lefor, Kiichi Tamada, Hironori Yamamoto
A 21-year-old female underwent a Kasai hepatoportoenterostomy with Roux-en-Y reconstruction for typeIII biliary atresia at age 63 days. At the age of 19 years, she developed cholangitis and CT scan revealed hepatolithiasis. She presented for treatment of the intrahepatic stone and the hepatportoenterostomy was directly visualized with double-balloon endoscopy (DBE). Endoscopic findings showed multiple intrahepatic bile ducts open to the jejunum through multiple orifices. Cholangiography showed narrowing of intrahepatic bile duct branches with a "fire-like" appearance...
September 2016: Journal of Pediatric Surgery
Xu Sun, Mei Diao, Xuanzhao Wu, Wei Cheng, Mao Ye, Long Li
OBJECTIVE: The objective of the study is to evaluate the outcome of laparoscopic Kasai portoenterostomy for type III biliary atresia in children. METHODS: A total of 95 type III biliary atresia patients were treated at the Capital Institute of Pediatrics between September 2009 and August 2011. The patients were randomized into 2 groups preoperatively: the laparoscopic group (LP group, n=48) and the open group (OP group, n=47). In the LP group, 4 patients were converted to open operations, whereas the remaining 44 patients in the LP group and 47 patients in the OP group were included in the study...
March 2016: Journal of Pediatric Surgery
Sinobol Chusilp, Paiboon Sookpotarom, Kanokan Tepmalai, Prapapan Rajatapiti, Voranush Chongsrisawat, Yong Poovorawan, Paisarn Vejchapipat
BACKGROUND: Biliary atresia (BA) is a serious liver disease with uncertain prognosis. The objective of this study was to investigate prognostic values of the >20 % decrease in serum total bilirubin (TB) at 7th day post-op regarding early outcome and 5-year survival with native liver in BA. METHODS: Biliary atresia patients undergoing Kasai operation between 2000 and 2014 were reviewed. The ratio of serum TB at 7th day post-op to pre-op TB levels (TB7/TB0) was calculated for every patient...
October 2016: Pediatric Surgery International
Neha Santucci, Sunny Z Hussain, Carroll M Harmon, Julie H Schiavo, Paul E Hyman
OBJECTIVES: Cholecystectomy rates for biliary dyskinesia in children are rising in the United States, but not in other countries. Biliary dyskinesia is a validated functional gallbladder disorder in adults, requiring biliary colic in the diagnosis. In contrast, most studies in children require upper abdominal pain, absent gallstones on ultrasound and an abnormal gallbladder ejection fraction (GBEF) on cholecystokinin-stimulated cholescintigraphy for diagnosis. We aimed to systematically review existing literature in biliary dyskinesia in children, determine the validity and reliability of diagnostic criteria, GBEF, and to assess outcomes following cholecystectomy...
July 28, 2016: Journal of Pediatric Gastroenterology and Nutrition
Hideyuki Sasaki, Hiromu Tanaka, Motoshi Wada, Takuro Kazama, Megumi Nakamura, Hironori Kudo, Ryoji Okubo, Tsuyoshi Sakurai, Masaki Nio
PURPOSE: Long-term survivors of biliary atresia (BA) sometimes experience liver dysfunction. We evaluated the prognostic factors for long-term native liver survival (NLS) in BA patients after the Kasai procedure. METHODS: This study included 67 patients with jaundice disappearance after the Kasai procedure performed between 1972 and 1995, and NLS for over 10 years. We retrospectively evaluated the clinical parameters, including the type of BA, age at the Kasai procedure, medical conditions, and treatments...
September 2016: Pediatric Surgery International
Rima Fawaz, Ulrich Baumann, Udeme Ekong, Björn Fischler, Nedim Hadzic, Cara L Mack, Valérie A McLin, Jean P Molleston, Ezequiel Neimark, Vicky Lee Ng, Saul J Karpen
Cholestatic jaundice in infancy affects approximately 1 in every 2500 term infants and is infrequently recognized by primary providers in the setting of physiologic jaundice. Cholestatic jaundice is always pathologic and indicates hepatobiliary dysfunction. Early detection by the primary care physician and timely referrals to the pediatric gastroenterologist/hepatologist are important contributors to optimal treatment and prognosis. The most common causes of cholestatic jaundice in the first months of life are biliary atresia (BA, 25-40%) followed by an expanding list of monogenic disorders (25%), plus many unknown or multifactorial (e...
July 16, 2016: Journal of Pediatric Gastroenterology and Nutrition
Joseph J Palermo, Tom K Lin, Lindsey Hornung, C Alexander Valencia, Abhinav Mathur, Kimberly Jackson, Lin Fei, Maisam Abu-El-Haija
OBJECTIVES: The aim of this study was to determine if comprehensive genetic testing was useful to identify genetic variants that discriminate chronic pancreatitis (CP) from acute recurrent pancreatitis (ARP) in a pediatric population. METHODS: We conducted a retrospective review of 50 patients enrolled in our institutional pancreatitis registry between April 2013 and January 2015. Genetic analysis of PRSS1, CFTR, SPINK1, and CTRC classified variants as mutations or variants of unknown clinical significance and the minor allele frequency of variants in our cohort was obtained...
October 2016: Pancreas
Flora K Szabo, Lin Fei, Ligia Alfaro Cruz, Maisam Abu-El-Haija
OBJECTIVES: To determine whether recommendations for treatment of acute pancreatitis (AP) in adults impact the outcomes of pediatric AP. STUDY DESIGN: Adult guidelines regarding early management of AP were implemented through an admission order set at Cincinnati Children's Hospital Medical Center at the beginning of the year 2014. Recommendations included administering high rates of intravenous fluid (IVF) within 24 hours of admission and enteral nutrition within 48 hours of admission...
August 2015: Journal of Pediatrics
Flora K Szabo, Lindsey Hornung, Judy-April Oparaji, Rabea Alhosh, Sohail Z Husain, Quin Y Liu, Joseph Palermo, Tom K Lin, Jaimie D Nathan, Daniel J Podberesky, Mark Lowe, Lin Fei, Maisam Abu-El-Haija
BACKGROUND/OBJECTIVES: Approximately 15-20% of pediatric patients with acute pancreatitis (AP) develop severe disease. Severity scoring tools were developed for adult patients, but have limitations when applied in children. We aimed to identify early predictors of severe acute pancreatitis (SAP) on hospital admission for early risk stratification of patients. METHODS: Retrospective review of AP admissions was conducted. The derivation cohort included cases at Cincinnati Children's Hospital Medical Center (CCHMC) between 2009 and 2013...
May 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Maisam Abu-El-Haija, Tom K Lin, Joseph Palermo
Acute pancreatitis is an emerging problem in pediatrics, with an incidence that is rising in the last 2 decades. Data regarding the optimal management and physician practice patterns are lacking. We present a literature review and updates on the management of pediatric pancreatitis. Prospective multicenter studies defining optimal management of pediatric pancreatitis are needed to guide care and improve outcomes for this patient population.
June 2014: Journal of Pediatric Gastroenterology and Nutrition
Tom K Lin, Joseph J Palermo, Jaimie D Nathan, Gregory M Tiao, Lindsey N Hornung, Lin Fei, Maisam Abu-El-Haija
BACKGROUND: Biliary pancreatitis (BP) is common in adults and children. Current standard of care is to perform a cholecystectomy (CCE) to decrease the recurrence risk of pancreatitis. Controversy exists as to the timing of surgery, early versus delayed surgical intervention. Adult literature suggests a greater benefit of early CCE. Comparatively, there is limited pediatric literature as to the optimal timing of a CCE in children. We report a retrospective case series of children with BP who underwent early versus late CCE...
January 2016: Journal of Pediatric Gastroenterology and Nutrition
Maisam Abu-El-Haija, Rebecca Wilhelm, Christie Heinzman, Bruna Nabuco Freire Siqueira, Yuanshu Zou, Lin Fei, Conrad R Cole
Nutrition is an integral part of acute pancreatitis (AP) management and is not adequately studied in pediatrics. The goal from the present study was to evaluate the effect of nutrition and fat content on the length of stay and pain severity in patients with AP. This is a retrospective review of our nutrition database between May 1, 2014 and December 1, 2014. Pain levels were similar between patients who were allowed to feed and patients kept nill per os. Higher fat intake grams per kilogram per day was associated with significantly lower pain scores...
March 2016: Journal of Pediatric Gastroenterology and Nutrition
Soma Kumar, Chee Y Ooi, Steven Werlin, Maisam Abu-El-Haija, Bradley Barth, Melena D Bellin, Peter R Durie, Douglas S Fishman, Steven D Freedman, Cheryl Gariepy, Matthew J Giefer, Tanja Gonska, Melvin B Heyman, Ryan Himes, Sohail Z Husain, Tom K Lin, Mark E Lowe, Veronique Morinville, Joseph J Palermo, John F Pohl, Sarah Jane Schwarzenberg, David Troendle, Michael Wilschanski, M Bridget Zimmerman, Aliye Uc
IMPORTANCE: Pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) are poorly understood. OBJECTIVE: To characterize and identify risk factors associated with ARP and CP in childhood. DESIGN, SETTING, AND PARTICIPANTS: A multinational cross-sectional study of children with ARP or CP at the time of enrollment to the INSPPIRE (International Study Group of Pediatric Pancreatitis: In Search for a Cure) study at participant institutions of the INSPPIRE Consortium...
June 1, 2016: JAMA Pediatrics
Fabao Hao, Hongjie Guo, Qianfu Luo, Chunbao Guo
BACKGROUND: Approximately 10% of patients with acute pancreatitis (AP) progress to chronic pancreatitis. Little is known about the factors that affect recurrence of pancreatitis after an initial episode. We retrospectively investigated patients with AP, focusing on their outcomes and the predictors for disease progression. METHODS: Between July 2003 and June 2015, we retrospectively enrolled first-time AP patients with medical records on disease etiology, severity (according to the Atlanta classifications), and recurrence of AP...
May 15, 2016: Journal of Surgical Research
2016-06-13 01:53:11
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