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STOPP/START

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180 papers 25 to 100 followers
By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
https://www.readbyqxmd.com/read/29766391/medication-related-problems-among-adult-chronic-kidney-disease-patients-in-a-sub-saharan-tertiary-hospital
#1
Lisper Wangeci Njeri, William Otieno Ogallo, David Gitonga Nyamu, Sylvia Adisa Opanga, Alfred Rugendo Birichi
BACKGROUND: Chronic kidney disease (CKD) patients are prone to medication-related problems (MRPs). Few studies address the clinical relevance of MRPs among CKD patients in sub-Saharan Africa. OBJECTIVE: To investigate the frequency and predictors of MRPs among adult CKD patients treated at a tertiary care facility in an urban sub-Saharan setting. SETTING: Kenyatta National Hospital in Nairobi, Kenya. METHOD: A cross-sectional study involving 60 adult patients with CKD was carried out...
May 15, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29744901/hospital-readmissions-mortality-and-potentially-inappropriate-prescribing-a-retrospective-study-of-older-adults-discharged-from-hospital
#2
David Counter, James W T Millar, James S McLay
AIMS: Applying version 2 of the STOPP/START criteria to discharge prescriptions of older adults discharged from a general medical unit, assess potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs)and their association with hospital readmission and mortality. METHODS: Discharge medications, co-morbidities and patient demographics were recorded over an 8 month period for consecutive emergency admissions aged ≥ 65 years. PIMs and PPOs were identified using version 2 of the STOPP/START criteria...
May 9, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29751840/prevalence-of-the-potentially-inappropriate-kampo-medications-to-be-used-with-caution-among-elderly-patients-taking-any-prescribed-kampo-medications-at-a-single-centre-in-japan-a-retrospective-cross-sectional-study
#3
Junpei Komagamine, Kazuhiko Hagane
BACKGROUND: Few studies have investigated the prevalence and characteristics of potentially inappropriate Kampo medication use among elderly ambulatory patients taking any prescribed Kampo medications. METHODS: A retrospective cross-sectional study was conducted using electronic medical records. All patients aged 65 years or older who continued visiting internal medicine physicians and were prescribed any Kampo medications from January 2015 to March 2015 were included...
May 11, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29674846/costs-of-medication-in-older-patients-before-and-after-comprehensive-geriatric-assessment
#4
Gulcin Done Unutmaz, Pinar Soysal, Busra Tuven, Ahmet Turan Isik
Background: Polypharmacy and inappropriate drug use cause numerous complications, such as cognitive impairment, frailty, falls, and functional dependence. The present study aimed to determine the effect of the comprehensive geriatric assessment (CGA) on polypharmacy, potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), and to evaluate the economic reflections of medication changes. Methods: One thousand five hundred and seventy-nine older patients, who had undergone CGA, were retrospectively evaluated...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29669046/nephrology-comanagement-and-the-quality-of-antibiotic-prescribing-in-primary-care-for-patients-with-chronic-kidney-disease-a-retrospective-cross-sectional-study
#5
Justin X G Zhu, Danielle M Nash, Eric McArthur, Alexandra Farag, Amit X Garg, Arsh K Jain
Background: In primary care, patients with chronic kidney disease (CKD) are frequently prescribed excessive doses of antibiotics relative to their kidney function. We examined whether nephrology comanagement is associated with improved prescribing in primary care. Methods: In a retrospective propensity score-matched cross-sectional study, we studied the appropriateness of antibiotic prescriptions by primary care physicians to Ontarians ≥66 years of age with CKD Stages 4 and 5 (estimated glomerular filtration rate <30 mL/min/1...
April 12, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29665270/european-repository-of-explicit-criteria-of-potentially-inappropriate-medications-in-old-age
#6
Ivana Ivanova, Monique Elseviers, Maarten Wauters, Thierry Christiaens, Robert Vander Stichele
AIM: Lack of electronic assessment of medication lists in electronic health records is a barrier for more generalized use of potentially inappropriate medications (PIM) lists, designed for older adults. The aim was to construct a European repository of explicit criteria on PIM, suitable for electronic assessment. METHODS: PIM description, medication information, clinical information and level of evidence was entered. Criteria with unclear medication specifications were excluded...
April 17, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29635335/risk-profile-quality-of-life-and-care-of-patients-with-moderate-and-advanced-ckd-the-french-ckd-rein-cohort-study
#7
Bénédicte Stengel, Marie Metzger, Christian Combe, Christian Jacquelinet, Serge Briançon, Carole Ayav, Denis Fouque, Maurice Laville, Luc Frimat, Christophe Pascal, Yves-Edouard Herpe, Pascal Morel, Jean-François Deleuze, Joost P Schanstra, Céline Lange, Karine Legrand, Elodie Speyer, Sophie Liabeuf, Bruce M Robinson, Ziad A Massy
Background: The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study was designed to investigate the determinants of prognosis and care of patients referred to nephrologists with moderate and advanced chronic kidney disease (CKD). We examined their baseline risk profile and experience. Methods: We collected bioclinical and patient-reported information from 3033 outpatients with CKD and estimated glomerular filtration rates (eGFRs) of 15-60 mL/min/1...
April 9, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29611727/dose-adjustment-of-metformin-and-dipeptidyl-peptidase-iv-inhibitors-in-diabetic-patients-with-renal-dysfunction
#8
Cheli Melzer-Cohen, Avraham Karasik, Philipp J Leuschner, Joseph Azuri, Varda Shalev, Gabriel Chodick
OBJECTIVES: This analysis of real-world data aimed to (a) determine the proportion of Type II diabetes (T2DM) patients treated with metformin or dipeptidyl peptidase-4 inhibitors (DPP-4i) that require dose adjustment or therapy discontinuation due to chronic kidney disease (CKD), and (b) to assess the time required to dose adjustment from the time of worsening of CKD. METHODS: In this retrospective study, two study populations were defined in a large healthcare organization...
April 3, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29568537/a-province-wide-cross-sectional-study-of-demographics-and-medication-use-of-patients-in-hemodialysis-units-across-ontario
#9
Marisa Battistella, Racquel Jandoc, Jeremy Y Ng, Eric McArthur, Amit X Garg
Background: Hemodialysis patients are at an increased risk of polypharmacy as they have the highest pill burden of all chronically ill patient populations, with an estimated average of 12 medications per day. Objectives: The aim of this study was to evaluate prescribing patterns of outpatient medications in patients receiving in-center hemodialysis. This was done to identify potential candidate medications for future quality improvement initiations to optimize prescribing...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29567842/prevalence-of-potentially-inappropriate-prescribing-in-a-subpopulation-of-older-european-clinical-trial-participants-a-cross-sectional-study
#10
David O Riordan, Carole Elodie Aubert, Kieran A Walsh, Anette Van Dorland, Nicolas Rodondi, Robert S Du Puy, Rosalinde K E Poortvliet, Jacobijn Gussekloo, Carol Sinnott, Stephen Byrne, Rose Galvin, J Wouter Jukema, Simon P Mooijaart, Christine Baumgartner, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers, Manuel R Blum, Patricia M Kearney
OBJECTIVES: To estimate and compare the prevalence and type of potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) among community-dwelling older adults (≥65 years) enrolled to a clinical trial in three European countries. DESIGN: A secondary analysis of the Thyroid Hormone Replacement for Subclinical Hypothyroidism Trial dataset. PARTICIPANTS: A subset of 48/80 PIP and 22/34 PPOs indicators from the Screening Tool of Older Persons Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP/START) V2 criteria were applied to prescribed medication data for 532/737 trial participants in Ireland, Switzerland and the Netherlands...
March 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29529172/prescription-of-high-risk-medications-among-patients-with-chronic-kidney-disease-a-cross-sectional-study-from-the-washington-wyoming-alaska-montana-and-idaho-region-practice-and-research-network
#11
Janelle Guirguis-Blake, Gina A Keppel, John Holmes, Rex W Force, William Kriegsman, Laura-Mae Baldwin
Background: Patients with chronic kidney disease (CKD) are at high risk for adverse drug events related to medication dosing errors and prescriptions for relatively contraindicated medications, such as non-steroidal anti-inflammatory drugs (NSAIDs). Objectives: To examine the scope of and variation in prescribing relatively contraindicated medications and medications above the recommended dose levels among patients with stage III/IV CKD in primary care practice...
February 26, 2018: Family Practice
https://www.readbyqxmd.com/read/29495567/the-introduction-of-a-full-medication-review-process-in-a-local-hospital-successes-and-barriers-of-a-pilot-project-in-the-geriatric-ward
#12
Lies De Bock, Eline Tommelein, Hans Baekelandt, Wim Maes, Koen Boussery, Annemie Somers
For the majority of Belgian hospitals, a pharmacist-led full medication review process is not standard care and, therefore, challenging to introduce. With this study, we aimed to evaluate the successes and barriers of the implementation of a pharmacist-led full medication review process in the geriatric ward at a local Belgian hospital. To this end, we carried out an interventional study, performing a full medication review on older patients (≥70 years) with polypharmacy (≥5 drugs) who had an unplanned admission to the geriatric ward...
February 28, 2018: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29465873/-what-place-for-therapeutic-education-in-nephrology
#13
Anne Dufey Teso, Pascale Lefuel, Sophie de Seigneux, Aline Lassere-Moutet, Pierre-Yves Martin, Alain Golay
Chronic kidney disease (CKD) usually goes unrecognized for patients until late symptomatic stages. In preterminal CKD, extrarenal substitution methods are usually presented to patients. This is felt like a breakdown, implying major modifications of everyday life. Acquisition of health literacy is necessary for patients with CKD to become autonomous and increase their empowerment toward the disease. Therapeutic education in nephrology plays a major role in improving the care of CKD patients.
February 21, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29442099/prescribing-or-deprescribing-in-older-persons-what-are-the-real%C3%A2-life-concerns-in-geriatric-practice
#14
Barbara Bień, Katarzyna Bień-Barkowska
INTRODUCTION    Multimorbidity in older adults leads to polypharmacy with all its hazardous outcomes and drug‑related problems. OBJECTIVES    We aimed to assess the difference in the number of drugs between admission to and discharge from a geriatric ward and identified the patient‑related factors associated with changes in the drug regimen. PATIENTS AND METHODS    This retrospective cross‑sectional study included 301 geriatric patients who underwent drug optimization in line with the Beers and STOPP/START criteria...
April 30, 2018: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29384023/prevalence-and-management-of-drug-related-problems-in-chronic-kidney-disease-patients-by-severity-level-a-subanalysis-of-a-cluster-randomized-controlled-trial-in-community-pharmacies
#15
Patricia Quintana-Bárcena, Anne Lord, Annie Lizotte, Djamal Berbiche, Lyne Lalonde
BACKGROUND: Drug-related problems (DRPs) are prevalent among chronic kidney disease (CKD) patients. However, little is known about their severity and management by community pharmacists. OBJECTIVES: To (a) describe the prevalence of DRPs by severity level in CKD patients and (b) assess the effect of a training-and-communication network program in nephrology (ProFiL) on these DRPs. METHODS: This is a secondary analysis of a cluster randomized controlled trial evaluating the effect of the ProFiL-program...
February 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29379953/effect-of-an-in-hospital-multifaceted-clinical-pharmacist-intervention-on-the-risk-of-readmission-a-randomized-clinical-trial
#16
Lene Vestergaard Ravn-Nielsen, Marie-Louise Duckert, Mia Lolk Lund, Jolene Pilegaard Henriksen, Michelle Lyndgaard Nielsen, Christina Skovsende Eriksen, Thomas Croft Buck, Anton Pottegård, Morten Rix Hansen, Jesper Hallas
Importance: Hospital readmissions are common among patients receiving multiple medications, with considerable costs to the patients and society. Objective: To determine whether a multifaceted pharmacist intervention based on medication review, patient interview, and follow-up can reduce the number of readmissions and emergency department (ED) visits. Design, Setting, and Participants: This randomized clinical multicenter study (Odense Pharmacist Trial Investigating Medication Interventions at Sector Transfer [OPTIMIST]) enrolled patients from September 1, 2013, through April 23, 2015, with a follow-up of 6 months completed on October 31, 2015...
March 1, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29360070/-reduction-of-inappropriate-prescriptions-and-adverse-effects-to-medications-in-hospitalized-elderly-patients
#17
Ana Fajreldines, Eduardo Schnitzler, Jorge T Insua, Mariana Valerio, Laura Davide, Marcelo Pellizzari
Together, potentially inappropriate prescribing of medications (PIP) and appropriate prescribing omission (APO) constitute a problem that requires multiple interventions to reduce its size and the occurrence of adverse drug events (ADE). This study aims to assess PIP, APO, ADE before and after the intervention of a clinical pharmacist over medical prescriptions for elderly hospitalized patients. In a before-after study, a total of 16 542 prescriptions for 1262 patients were analyzed applying the criteria defined in both STOPP- START (screening tool of older people's prescriptions and screening tool to alert to right treatment)...
2018: Medicina
https://www.readbyqxmd.com/read/24969386/medication-pitfalls-in-the-ckd-clinic-case-presentations
#18
REVIEW
Anne Marie Liles
The kidney plays a major role in pharmacokinetics and pharmacodynamics of drugs; therefore, medication errors can result from failure to properly adjust medications in patients with CKD. It is the responsibility of all health-care providers to work collectively when reviewing medications, initiating new medications, and adjusting doses of current medications. Awareness of appropriate dosing recommendations can significantly decrease medication error-associated morbidity, mortality, and cost.
July 2014: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/29322470/associations-between-the-drug-burden-index-potentially-inappropriate-medications-and-quality-of-life-in-residential-aged-care
#19
Stephanie L Harrison, Lisa Kouladjian O'Donnell, Clare E Bradley, Rachel Milte, Suzanne M Dyer, Emmanuel S Gnanamanickam, Enwu Liu, Sarah N Hilmer, Maria Crotty
BACKGROUND: Inappropriate polypharmacy may negatively impact the quality of life of residents in aged care facilities, but it remains unclear which medications may influence this reduced quality of life. OBJECTIVE: The objective of this study was to examine whether the Drug Burden Index and potentially inappropriate medications were associated with quality of life in older adults living in residential care with a high prevalence of cognitive impairment and dementia...
January 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29301226/impact-of-pharmacist-conducted-comprehensive-medication-reviews-for-older-adult-patients-to-reduce-medication-related-problems
#20
Whitney J Kiel, Shaun W Phillips
Older adults are demanding increased healthcare attention with regards to prescription use due in large part to highly complex medication regimens. As patients age, medications often have a more pronounced effect on older adults, negatively impacting patient safety and increasing healthcare costs. Comprehensive medication reviews (CMRs) optimize medications for elderly patients and help to avoid inappropriate medication use. Previous literature has shown that such CMRs can successfully identify and reduce the number of medication-related problems and improve acute healthcare utilization...
December 31, 2017: Pharmacy (Basel, Switzerland)
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