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STOPP/START

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191 papers 25 to 100 followers
By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
https://www.readbyqxmd.com/read/29969992/identifying-drug-substances-of-screening-tool-for-older-persons-appropriate-prescriptions-for-japanese
#1
Kaori Nomura, Taro Kojima, Shinya Ishii, Takuto Yonekawa, Masahiro Akishita, Manabu Akazawa
BACKGROUND: In 2015, the Japan Geriatric Society (JGS) updated "the Guidelines for Medical Treatment and its Safety in the elderly," accompanied with the Screening Tool for Older Persons' Appropriate Prescriptions for Japanese (STOPP-J): "drugs to be prescribed with special caution" and "drugs to consider starting." The JGS proposed the STOPP-J to contribute to improving prescribing quality; however, each decision should be carefully based on medical knowledge...
July 3, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29916139/contribution-of-patient-interviews-as-part-of-a-comprehensive-approach-to-the-identification-of-drug-related-problems-on-geriatric-wards
#2
Dominik Stämpfli, Fabienne Boeni, Andy Gerber, Victor A D Bättig, Kurt E Hersberger, Markus L Lampert
BACKGROUND: Inappropriate prescribing is linked to increased risks for adverse drug reactions and hospitalisation. Combining explicit and implicit criteria of inappropriate prescribing with the information obtained in patient interviews seems beneficial with regard to the identification of drug-related problems (DRPs) in hospitalised patients. OBJECTIVE: We aimed to investigate the inclusion of pharmacist interviews as part of medication reviews (including the use of explicit and implicit criteria of inappropriate prescribing) to identify DRPs in older inpatients...
June 19, 2018: Drugs & Aging
https://www.readbyqxmd.com/read/29915131/medication-safety-principles-and-practice-in-ckd
#3
Chanel F Whittaker, Margaret A Miklich, Roshni S Patel, Jeffrey C Fink
Ensuring patient safety is a priority of medical care because iatrogenic injury has been a primary concern. Medications are an important source of medical errors, and kidney disease is a thoroughfare of factors threatening safe administration of medicines. Principal among these is reduced kidney function because almost half of all medications used are eliminated via the kidney. Additionally, kidney patients often suffer from multimorbidity, including diabetes, hypertension, and heart failure, with a range of prescribers who often do not coordinate treatments...
June 18, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29903667/-the-most-common-stopp-start-criteria-in-spain-a-review-of-the-literature
#4
Esther Salgueiro, Bryana Candelaria Elizarde, Ana Isabel Elola, Beatriz García-Pulido, María Luisa Nicieza-García, Gloria Manso
OBJECTIVE: To analyse STOPP/START criteria found most frequently in the studies carried out in Spain, in order to identify the main areas of potentially inappropriate prescribing. METHODS: A literature review was carried out on the original studies performed in Spain that applied the original version of the STOPP/START criteria and that described the most common STOPP and/or START criteria found. In each study, a weighted analysis was performed on the criteria found, by assigning 5 points to the criterion in first position, 4 points to the criterion in second position, and so on to fifth criterion...
June 11, 2018: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29898484/-drug-prescribing-for-patients-with-chronic-kidney-disease-in-general-practice-a-cross-sectional-study
#5
Maria Mahner, Christina Raus, Fabian Ludwig, Gesine Weckmann, Sylvia Stracke, Jean-François Chenot
BACKGROUND:  Many drugs require dose adjustment or are contraindicated in patients with chronic kidney disease (CKD) to avoid adverse events. The aims of this study were to assess if medication was appropriately dose adjusted in patients with CKD in primary care, to identify medications that were frequently prescribed inappropriately and to identify factors predicting mal-prescription. METHODS:  We conducted a cross-sectional observational study in 34 general practioners' offices, assessing the medication of patients with CKD stage ≥ 3 according to the corresponding pharmaceutical product information...
June 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29895004/can-emergency-department-visits-for-adverse-drug-reactions-in-dialysis-patients-be-reduced
#6
EDITORIAL
Simit Doshi, Jay B Wish
No abstract text is available yet for this article.
2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29895030/national-trends-in-emergency-room-visits-of-dialysis-patients-for-adverse-drug-reactions
#7
Lili Chan, Aparna Saha, Priti Poojary, Kinsuk Chauhan, Nidhi Naik, Steven Coca, Pranav S Garimella, Girish N Nadkarni
BACKGROUND: Various medications are cleared by the kidneys, therefore patients with impaired renal function, especially dialysis patients are at risk for adverse drug events (ADEs). There are limited studies on ADEs in maintenance dialysis patients. METHODS: We utilized a nationally representative database, the Nationwide Emergency Department Sample, from 2008 to 2013, to compare emergency department (ED) visits for dialysis and propensity matched non-dialysis patients...
June 12, 2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29895031/iatrogenesis-imperfecta-medicamentosa-adverse-drug-events-in-dialysis-patients-are-associated-with-higher-resource-utilization-and-mortality
#8
EDITORIAL
Daniel Blum, Christopher T Chan
No abstract text is available yet for this article.
June 12, 2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29877182/potentially-inappropriate-prescribing-in-elderly-patient-analyze-before-after-hospitalization
#9
Ludovic Argoullon, Marie-Agnès Manciaux, Aude Valance, Amélie Bonneville
In the context of improved medication management in the elderly patient, we were interested in the reevaluation of drug prescription during hospitalization. The aim of this study is to assess the prevalence of inappropriate prescribing in the elderly patient before and after hospitalization. PATIENTS AND METHODS: This is a descriptive and retrospective study of drug prescriptions in a non-geriatric unit. Prescriptions were analyzed using STOPP/START tool. RESULTS: Seventy-two patients over 65 years-old were included...
June 1, 2018: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/29869294/pharmacist-led-medication-assessment-and-deprescribing-intervention-for-older-adults-with-cancer-and-polypharmacy-a-pilot-study
#10
Andrew Whitman, Kathlene DeGregory, Amy Morris, Supriya Mohile, Erika Ramsdale
PURPOSE: The aims of this study were to compare the application of three geriatric medication screening tools to the Beers Criteria alone for potentially inappropriate medication quantification and to determine feasibility of a pharmacist-led polypharmacy assessment in a geriatric oncology clinic. METHODS: Adult patients with cancer aged 65 and older underwent a comprehensive geriatric assessment. A polypharmacy assessment was completed by a pharmacist and included a review of all drug therapies...
June 4, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29780106/a-survey-of-drug-burden-in-patients-undergoing-maintenance-hemodialysis-in-japan
#11
Yuko Iwashita, Masaki Ohya, Satoko Kunimoto, Yu Iwashita, Toru Mima, Shigeo Negi, Takashi Shigematsu
Objective This report presents a part of a survey pertaining to drug burden in maintenance hemodialysis patients in Japan. Methods A patient-reported questionnaire-based survey was conducted from September to November 2016 in six regions in Japan. Patients or Materials A total of 700 patients (50-79 years old) on maintenance hemodialysis for >3 years and members of the Japan Association of Kidney Disease Patients (JAKDP) were provided with the questionnaire. They were randomly selected using stratified sampling according to patient distribution observed from the Japanese Society for Dialysis Therapy Renal Data Registry (JSDT JRDR)...
May 18, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29766391/medication-related-problems-among-adult-chronic-kidney-disease-patients-in-a-sub-saharan-tertiary-hospital
#12
Lisper Wangeci Njeri, William Otieno Ogallo, David Gitonga Nyamu, Sylvia Adisa Opanga, Alfred Rugendo Birichi
BACKGROUND: Chronic kidney disease (CKD) patients are prone to medication-related problems (MRPs). Few studies address the clinical relevance of MRPs among CKD patients in sub-Saharan Africa. OBJECTIVE: To investigate the frequency and predictors of MRPs among adult CKD patients treated at a tertiary care facility in an urban sub-Saharan setting. SETTING: Kenyatta National Hospital in Nairobi, Kenya. METHOD: A cross-sectional study involving 60 adult patients with CKD was carried out...
May 15, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29744901/hospital-readmissions-mortality-and-potentially-inappropriate-prescribing-a-retrospective-study-of-older-adults-discharged-from-hospital
#13
David Counter, James W T Millar, James S McLay
AIMS: Applying version 2 of the STOPP/START criteria to discharge prescriptions of older adults discharged from a general medical unit, the aim of this study is to assess potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) and their association with hospital readmission and mortality. METHODS: Discharge medications, co-morbidities and patient demographics were recorded over an 8-month period for consecutive emergency admissions of patients aged ≥65 years...
May 9, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29751840/prevalence-of-the-potentially-inappropriate-kampo-medications-to-be-used-with-caution-among-elderly-patients-taking-any-prescribed-kampo-medications-at-a-single-centre-in-japan-a-retrospective-cross-sectional-study
#14
Junpei Komagamine, Kazuhiko Hagane
BACKGROUND: Few studies have investigated the prevalence and characteristics of potentially inappropriate Kampo medication use among elderly ambulatory patients taking any prescribed Kampo medications. METHODS: A retrospective cross-sectional study was conducted using electronic medical records. All patients aged 65 years or older who continued visiting internal medicine physicians and were prescribed any Kampo medications from January 2015 to March 2015 were included...
May 11, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29674846/costs-of-medication-in-older-patients-before-and-after-comprehensive-geriatric-assessment
#15
Gulcin Done Unutmaz, Pinar Soysal, Busra Tuven, Ahmet Turan Isik
Background: Polypharmacy and inappropriate drug use cause numerous complications, such as cognitive impairment, frailty, falls, and functional dependence. The present study aimed to determine the effect of the comprehensive geriatric assessment (CGA) on polypharmacy, potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), and to evaluate the economic reflections of medication changes. Methods: One thousand five hundred and seventy-nine older patients, who had undergone CGA, were retrospectively evaluated...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29669046/nephrology-comanagement-and-the-quality-of-antibiotic-prescribing-in-primary-care-for-patients-with-chronic-kidney-disease-a-retrospective-cross-sectional-study
#16
Justin X G Zhu, Danielle M Nash, Eric McArthur, Alexandra Farag, Amit X Garg, Arsh K Jain
Background: In primary care, patients with chronic kidney disease (CKD) are frequently prescribed excessive doses of antibiotics relative to their kidney function. We examined whether nephrology comanagement is associated with improved prescribing in primary care. Methods: In a retrospective propensity score-matched cross-sectional study, we studied the appropriateness of antibiotic prescriptions by primary care physicians to Ontarians ≥66 years of age with CKD Stages 4 and 5 (estimated glomerular filtration rate <30 mL/min/1...
April 12, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29665270/european-repository-of-explicit-criteria-of-potentially-inappropriate-medications-in-old-age
#17
Ivana Ivanova, Monique Elseviers, Maarten Wauters, Thierry Christiaens, Robert Vander Stichele
AIM: Lack of electronic assessment of medication lists in electronic health records is a barrier for more generalized use of potentially inappropriate medications (PIM) lists, designed for older adults. The aim was to construct a European repository of explicit criteria on PIM, suitable for electronic assessment. METHODS: PIM description, medication information, clinical information and level of evidence was entered. Criteria with unclear medication specifications were excluded...
April 17, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29635335/risk-profile-quality-of-life-and-care-of-patients-with-moderate-and-advanced-ckd-the-french-ckd-rein-cohort-study
#18
Bénédicte Stengel, Marie Metzger, Christian Combe, Christian Jacquelinet, Serge Briançon, Carole Ayav, Denis Fouque, Maurice Laville, Luc Frimat, Christophe Pascal, Yves-Edouard Herpe, Pascal Morel, Jean-François Deleuze, Joost P Schanstra, Céline Lange, Karine Legrand, Elodie Speyer, Sophie Liabeuf, Bruce M Robinson, Ziad A Massy
Background: The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study was designed to investigate the determinants of prognosis and care of patients referred to nephrologists with moderate and advanced chronic kidney disease (CKD). We examined their baseline risk profile and experience. Methods: We collected bioclinical and patient-reported information from 3033 outpatients with CKD and estimated glomerular filtration rates (eGFRs) of 15-60 mL/min/1...
April 9, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29611727/dose-adjustment-of-metformin-and-dipeptidyl-peptidase-iv-inhibitors-in-diabetic-patients-with-renal-dysfunction
#19
Cheli Melzer-Cohen, Avraham Karasik, Philipp J Leuschner, Joseph Azuri, Varda Shalev, Gabriel Chodick
OBJECTIVES: This analysis of real-world data aimed to (a) determine the proportion of Type II diabetes (T2DM) patients treated with metformin or dipeptidyl peptidase-4 inhibitors (DPP-4i) that require dose adjustment or therapy discontinuation due to chronic kidney disease (CKD), and (b) to assess the time required to dose adjustment from the time of worsening of CKD. METHODS: In this retrospective study, two study populations were defined in a large healthcare organization...
May 3, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29568537/a-province-wide-cross-sectional-study-of-demographics-and-medication-use-of-patients-in-hemodialysis-units-across-ontario
#20
Marisa Battistella, Racquel Jandoc, Jeremy Y Ng, Eric McArthur, Amit X Garg
Background: Hemodialysis patients are at an increased risk of polypharmacy as they have the highest pill burden of all chronically ill patient populations, with an estimated average of 12 medications per day. Objectives: The aim of this study was to evaluate prescribing patterns of outpatient medications in patients receiving in-center hemodialysis. This was done to identify potential candidate medications for future quality improvement initiations to optimize prescribing...
2018: Canadian Journal of Kidney Health and Disease
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