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COPD exacerbation executive summary 2014

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3 papers 0 to 25 followers
By Jason Mann No BS pulmonary critical care fellow
https://www.readbyqxmd.com/read/18555912/effect-of-carbocisteine-on-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-peace-study-a-randomised-placebo-controlled-study
#1
RANDOMIZED CONTROLLED TRIAL
Jin-Ping Zheng, Jian Kang, Shao-Guang Huang, Ping Chen, Wan-Zen Yao, Lan Yang, Chun-Xue Bai, Chang-Zheng Wang, Chen Wang, Bao-Yuan Chen, Yi Shi, Chun-Tao Liu, Ping Chen, Qiang Li, Zhen-Shan Wang, Yi-Jiang Huang, Zhi-Yang Luo, Fei-Peng Chen, Jian-Zhang Yuan, Ben-Tong Yuan, Hui-Ping Qian, Rong-Chang Zhi, Nan-Shan Zhong
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation, and has many components including mucus hypersecretion, oxidative stress, and airway inflammation. We aimed to assess whether carbocisteine, a mucolytic agent with anti-inflammatory and antioxidation activities, could reduce the yearly exacerbation rate in patients with COPD. METHODS: We did a randomised, double-blind, placebo-controlled study of 709 patients from 22 centres in China...
June 14, 2008: Lancet
https://www.readbyqxmd.com/read/25321320/prevention-of-acute-exacerbations-of-copd-american-college-of-chest-physicians-and-canadian-thoracic-society-guideline
#2
REVIEW
Gerard J Criner, Jean Bourbeau, Rebecca L Diekemper, Daniel R Ouellette, Donna Goodridge, Paul Hernandez, Kristen Curren, Meyer S Balter, Mohit Bhutani, Pat G Camp, Bartolome R Celli, Gail Dechman, Mark T Dransfield, Stanley B Fiel, Marilyn G Foreman, Nicola A Hanania, Belinda K Ireland, Nathaniel Marchetti, Darcy D Marciniuk, Richard A Mularski, Joseph Ornelas, Jeremy D Road, Michael K Stickland
BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of symptoms of cough, dyspnea, and sputum production) is a major contributor to worsening lung function, impairment in quality of life, need for urgent care or hospitalization, and cost of care in COPD. Research conducted over the past decade has contributed much to our current understanding of the pathogenesis and treatment of COPD...
April 2015: Chest
https://www.readbyqxmd.com/read/25320966/executive-summary-prevention-of-acute-exacerbation-of-copd-american-college-of-chest-physicians-and-canadian-thoracic-society-guideline
#3
REVIEW
Gerard J Criner, Jean Bourbeau, Rebecca L Diekemper, Daniel R Ouellette, Donna Goodridge, Paul Hernandez, Kristen Curren, Meyer S Balter, Mohit Bhutani, Pat G Camp, Bartolome R Celli, Gail Dechman, Mark T Dransfield, Stanley B Fiel, Marilyn G Foreman, Nicola A Hanania, Belinda K Ireland, Nathaniel Marchetti, Darcy D Marciniuk, Richard A Mularski, Joseph Ornelas, Jeremy D Road, Michael K Stickland
No abstract text is available yet for this article.
April 2015: Chest
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