Katherine R Tuttle, George L Bakris, Rudolf W Bilous, Jane L Chiang, Ian H de Boer, Jordi Goldstein-Fuchs, Irl B Hirsch, Kamyar Kalantar-Zadeh, Andrew S Narva, Sankar D Navaneethan, Joshua J Neumiller, Uptal D Patel, Robert E Ratner, Adam T Whaley-Connell, Mark E Molitch
The incidence and prevalence of diabetes mellitus have grown significantly throughout the world, due primarily to the increase in type 2 diabetes. This overall increase in the number of people with diabetes has had a major impact on development of diabetic kidney disease (DKD), one of the most frequent complications of both types of diabetes. DKD is the leading cause of end-stage renal disease (ESRD), accounting for approximately 50% of cases in the developed world. Although incidence rates for ESRD attributable to DKD have recently stabilized, these rates continue to rise in high-risk groups such as middle-aged African Americans, Native Americans, and Hispanics...
October 2014: American Journal of Kidney Diseases