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16 papers 0 to 25 followers
https://www.readbyqxmd.com/read/21247782/perioperative-use-of-arginine-supplemented-diets-a-systematic-review-of-the-evidence
#1
REVIEW
John W Drover, Rupinder Dhaliwal, Lindsay Weitzel, Paul E Wischmeyer, Juan B Ochoa, Daren K Heyland
No abstract text is available yet for this article.
March 2011: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/8948561/effect-on-the-duration-of-mechanical-ventilation-of-identifying-patients-capable-of-breathing-spontaneously
#2
RANDOMIZED CONTROLLED TRIAL
E W Ely, A M Baker, D P Dunagan, H L Burke, A C Smith, P T Kelly, M M Johnson, R W Browder, D L Bowton, E F Haponik
BACKGROUND: Prompt recognition of the reversal of respiratory failure may permit earlier discontinuation of mechanical ventilation, without harm to the patient. METHODS: We conducted a randomized, controlled trial in 300 adult patients receiving mechanical ventilation in medical and coronary intensive care units. In the intervention group, patients underwent daily screening of respiratory function by physicians, respiratory therapists, and nurses to identify those possibly capable of breathing spontaneously; successful tests were followed by two-hour trials of spontaneous breathing in those who met the criteria...
December 19, 1996: New England Journal of Medicine
https://www.readbyqxmd.com/read/2023603/a-prospective-study-of-indexes-predicting-the-outcome-of-trials-of-weaning-from-mechanical-ventilation
#3
K L Yang, M J Tobin
BACKGROUND: The traditional predictors of the outcome of weaning from mechanical ventilation--minute ventilation (VE) and maximal inspiratory pressure (Plmax)--are frequently inaccurate. We developed two new indexes: the first quantitates rapid shallow breathing as the ratio of respiratory frequency to tidal volume (f/VT), and the second is termed CROP, because it integrates thoracic compliance, respiratory rate, arterial oxygenation, and Plmax. METHODS: The threshold values for each index that discriminated best between a successful and an unsuccessful outcome of weaning were determined in 36 patients, and the predictive accuracy of these values was then tested prospectively in an additional 64 patients...
May 23, 1991: New England Journal of Medicine
https://www.readbyqxmd.com/read/10816184/daily-interruption-of-sedative-infusions-in-critically-ill-patients-undergoing-mechanical-ventilation
#4
RANDOMIZED CONTROLLED TRIAL
J P Kress, A S Pohlman, M F O'Connor, J B Hall
BACKGROUND: Conous infusions of sedative drugs in the intensive care unit may prolong the duration of mechanical ventilation, prolong the length of stay in the intensive care unit and the hospital, impede efforts to perform daily neurologic examinations, and increase the need for tests to assess alterations in mental status. Whether regular interruption of such infusions might accelerate recovery is not known. METHODS: We conducted a randomized, controlled trial involving 128 adult patients who were receiving mechanical ventilation and continuous infusions of sedative drugs in a medical intensive care unit...
May 18, 2000: New England Journal of Medicine
https://www.readbyqxmd.com/read/23269131/clinical-practice-guidelines-for-the-management-of-pain-agitation-and-delirium-in-adult-patients-in-the-intensive-care-unit
#5
REVIEW
Juliana Barr, Gilles L Fraser, Kathleen Puntillo, E Wesley Ely, Céline Gélinas, Joseph F Dasta, Judy E Davidson, John W Devlin, John P Kress, Aaron M Joffe, Douglas B Coursin, Daniel L Herr, Avery Tung, Bryce R H Robinson, Dorrie K Fontaine, Michael A Ramsay, Richard R Riker, Curtis N Sessler, Brenda Pun, Yoanna Skrobik, Roman Jaeschke
OBJECTIVE: To revise the "Clinical Practice Guidelines for the Sustained Use of Sedatives and Analgesics in the Critically Ill Adult" published in Critical Care Medicine in 2002. METHODS: The American College of Critical Care Medicine assembled a 20-person, multidisciplinary, multi-institutional task force with expertise in guideline development, pain, agitation and sedation, delirium management, and associated outcomes in adult critically ill patients. The task force, divided into four subcommittees, collaborated over 6 yr in person, via teleconferences, and via electronic communication...
January 2013: Critical Care Medicine
https://www.readbyqxmd.com/read/24476433/sedation-and-delirium-in-the-intensive-care-unit
#6
REVIEW
Michael C Reade, Simon Finfer
No abstract text is available yet for this article.
January 30, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/22287700/medical-management-of-hepatorenal-syndrome
#7
REVIEW
Andrew Davenport, Jawad Ahmad, Ali Al-Khafaji, John A Kellum, Yuri S Genyk, Mitra K Nadim
Hepatorenal syndrome (HRS) is defined as the occurrence of renal dysfunction in a patient with end-stage liver cirrhosis in the absence of another identifiable cause of renal failure. The prognosis of HRS remains poor, with a median survival without liver transplantation of <6 months. However, understanding the pathogenesis of HRS has led to the introduction of treatments designed to increase renal perfusion and mean arterial blood pressure using vasopressors and albumin, which has led to improvement in renal function in ∼50% of patients...
January 2012: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/25495432/american-geriatrics-society-abstracted-clinical-practice-guideline-for-postoperative-delirium-in-older-adults
#8
(no author information available yet)
The abstracted set of recommendations presented here provides essential guidance both on the prevention of postoperative delirium in older patients at risk of delirium and on the treatment of older surgical patients with delirium, and is based on the 2014 American Geriatrics Society (AGS) Guideline. The full version of the guideline, American Geriatrics Society Clinical Practice Guideline for Postoperative Delirium in Older Adults is available at the website of the AGS. The overall aims of the study were twofold: first, to present nonpharmacologic and pharmacologic interventions that should be implemented perioperatively for the prevention of postoperative delirium in older adults; and second, to present nonpharmacologic and pharmacologic interventions that should be implemented perioperatively for the treatment of postoperative delirium in older adults...
January 2015: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/24717459/empiric-antibiotic-treatment-reduces-mortality-in-severe-sepsis-and-septic-shock-from-the-first-hour-results-from-a-guideline-based-performance-improvement-program
#9
COMPARATIVE STUDY
Ricard Ferrer, Ignacio Martin-Loeches, Gary Phillips, Tiffany M Osborn, Sean Townsend, R Phillip Dellinger, Antonio Artigas, Christa Schorr, Mitchell M Levy
OBJECTIVES: Compelling evidence has shown that aggressive resuscitation bundles, adequate source control, appropriate antibiotic therapy, and organ support are cornerstone for the success in the treatment of patients with sepsis. Delay in the initiation of appropriate antibiotic therapy has been recognized as a risk factor for mortality. To perform a retrospective analysis on the Surviving Sepsis Campaign database to evaluate the relationship between timing of antibiotic administration and mortality...
August 2014: Critical Care Medicine
https://www.readbyqxmd.com/read/18596631/early-intensive-care-unit-mobility-therapy-in-the-treatment-of-acute-respiratory-failure
#10
Peter E Morris, Amanda Goad, Clifton Thompson, Karen Taylor, Bethany Harry, Leah Passmore, Amelia Ross, Laura Anderson, Shirley Baker, Mary Sanchez, Lauretta Penley, April Howard, Luz Dixon, Susan Leach, Ronald Small, R Duncan Hite, Edward Haponik
OBJECTIVE: Immobilization and subsequent weakness are consequences of critical illness. Despite the theoretical advantages of physical therapy to address this problem, it has not been shown that physical therapy initiated in the intensive care unit offers benefit. DESIGN AND SETTING: Prospective cohort study in a university medical intensive care unit that assessed whether a mobility protocol increased the proportion of intensive care unit patients receiving physical therapy vs...
August 2008: Critical Care Medicine
https://www.readbyqxmd.com/read/19318384/intensive-versus-conventional-glucose-control-in-critically-ill-patients
#11
RANDOMIZED CONTROLLED TRIAL
Simon Finfer, Dean R Chittock, Steve Yu-Shuo Su, Deborah Blair, Denise Foster, Vinay Dhingra, Rinaldo Bellomo, Deborah Cook, Peter Dodek, William R Henderson, Paul C Hébert, Stephane Heritier, Daren K Heyland, Colin McArthur, Ellen McDonald, Imogen Mitchell, John A Myburgh, Robyn Norton, Julie Potter, Bruce G Robinson, Juan J Ronco
BACKGROUND: The optimal target range for blood glucose in critically ill patients remains unclear. METHODS: Within 24 hours after admission to an intensive care unit (ICU), adults who were expected to require treatment in the ICU on 3 or more consecutive days were randomly assigned to undergo either intensive glucose control, with a target blood glucose range of 81 to 108 mg per deciliter (4.5 to 6.0 mmol per liter), or conventional glucose control, with a target of 180 mg or less per deciliter (10...
March 26, 2009: New England Journal of Medicine
https://www.readbyqxmd.com/read/23375419/procalcitonin-as-a-diagnostic-marker-for-sepsis-a-systematic-review-and-meta-analysis
#12
REVIEW
Christina Wacker, Anna Prkno, Frank M Brunkhorst, Peter Schlattmann
BACKGROUND: Procalcitonin is a promising marker for identification of bacterial infections. We assessed the accuracy and clinical value of procalcitonin for diagnosis of sepsis in critically ill patients. METHODS: We searched Medline, Embase, ISI Web of Knowledge, the Cochrane Library, Scopus, BioMed Central, and Science Direct, from inception to Feb 21, 2012, and reference lists of identified primary studies. We included articles written in English, German, or French that investigated procalcitonin for differentiation of septic patients--those with sepsis, severe sepsis, or septic shock--from those with a systemic inflammatory response syndrome of non-infectious origin...
May 2013: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/10793162/ventilation-with-lower-tidal-volumes-as-compared-with-traditional-tidal-volumes-for-acute-lung-injury-and-the-acute-respiratory-distress-syndrome-the-acute-respiratory-distress-syndrome-network
#13
RANDOMIZED CONTROLLED TRIAL
(no author information available yet)
BACKGROUND: Traditional approaches to mechanical ventilation use tidal volumes of 10 to 15 ml per kilogram of body weight and may cause stretch-induced lung injury in patients with acute lung injury and the acute respiratory distress syndrome. We therefore conducted a trial to determine whether ventilation with lower tidal volumes would improve the clinical outcomes in these patients. METHODS: Patients with acute lung injury and the acute respiratory distress syndrome were enrolled in a multicenter, randomized trial...
May 4, 2000: New England Journal of Medicine
https://www.readbyqxmd.com/read/23353941/surviving-sepsis-campaign-international-guidelines-for-management-of-severe-sepsis-and-septic-shock-2012
#14
R Phillip Dellinger, Mitchell M Levy, Andrew Rhodes, Djillali Annane, Herwig Gerlach, Steven M Opal, Jonathan E Sevransky, Charles L Sprung, Ivor S Douglas, Roman Jaeschke, Tiffany M Osborn, Mark E Nunnally, Sean R Townsend, Konrad Reinhart, Ruth M Kleinpell, Derek C Angus, Clifford S Deutschman, Flavia R Machado, Gordon D Rubenfeld, Steven A Webb, Richard J Beale, Jean-Louis Vincent, Rui Moreno
OBJECTIVE: To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. DESIGN: A consensus committee of 68 international experts representing 30 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict of interest policy was developed at the onset of the process and enforced throughout...
February 2013: Critical Care Medicine
https://www.readbyqxmd.com/read/23370917/comparison-of-the-berlin-definition-for-acute-respiratory-distress-syndrome-with-autopsy
#15
COMPARATIVE STUDY
Arnaud W Thille, Andrés Esteban, Pilar Fernández-Segoviano, José-Maria Rodriguez, José-Antonio Aramburu, Oscar Peñuelas, Irene Cortés-Puch, Pablo Cardinal-Fernández, José A Lorente, Fernando Frutos-Vivar
RATIONALE: A revised definition of clinical criteria for acute respiratory distress syndrome (ARDS), the Berlin definition, was recently established to classify patients according to their severity. OBJECTIVE: To evaluate the accuracy of these clinical criteria using diffuse alveolar damage (DAD) at autopsy as the reference standard. METHODS: All patients who died and had a clinical autopsy in our intensive care unit over a 20-year period (1991-2010) were included...
April 1, 2013: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/22357372/acute-respiratory-distress-syndrome-evaluation-and-management
#16
REVIEW
I Cortés, O Peñuelas, A Esteban
Acute respiratory distress syndrome (ARDS) is a life-threatening condition that affects patients admitted in the Intensive Care Units (ICUs) under mechanical ventilation. ARDS is a process of non-hydrostatic pulmonary edema and hypoxemia associated with a variety of conditions, resulting in a direct (e.g., pneumonia) or indirect (e.g., sepsis) lung injury and is associated with a significant morbidity and mortality. A large body of clinical and basic research has focused in ventilatory strategies and novel pharmacological therapies but, nowadays, treatment is mainly supportive...
March 2012: Minerva Anestesiologica
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