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Colorectal cancer

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6 papers 100 to 500 followers
By Faye Kehler Family Physician and GP Anesthetist since 1987 interested in all aspects of Medicine
https://www.readbyqxmd.com/read/23910411/recommended-intervals-between-screening-and-surveillance-colonoscopies
#1
REVIEW
Todd H Baron, Thomas C Smyrk, Douglas K Rex
Colonoscopy has become the mainstay for screening and surveillance of colorectal cancer. The guidelines for screening and surveillance colonoscopy have recently been updated, particularly in light of greater recognition of the importance of sessile serrated lesions in the role of cancer. It is important for practitioners to be aware of and understand the recommendations for screening and surveillance to optimize patient safety and to decrease health care use. We searched PubMed for articles and guidelines related to screening and surveillance of colonic polyps and serrated adenomas...
August 2013: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/25472702/predicting-the-risk-of-recurrent-adenoma-and-incident-colorectal-cancer-based-on-findings-of-the-baseline-colonoscopy
#2
Kimberly J Fairley, Jinhong Li, Michael Komar, Nancy Steigerwalt, Porat Erlich
OBJECTIVES: The decision tree underlying current practice guidelines for post polypectomy surveillance relies on risk stratification based on predictive attributes gleaned from adenomas removed on screening colonoscopy examination. Our primary aim was to estimate the magnitude of association between baseline adenoma attributes and the risk of adenoma recurrence and invasive colorectal adenocarcinoma (CRC). Our secondary aims were to estimate the adenoma detection rate (ADR) of surveillance compared with screening colonoscopies and describe time trends in preventive colonoscopy utilization...
2014: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/24693890/adenoma-detection-rate-and-risk-of-colorectal-cancer-and-death
#3
Douglas A Corley, Christopher D Jensen, Amy R Marks, Wei K Zhao, Jeffrey K Lee, Chyke A Doubeni, Ann G Zauber, Jolanda de Boer, Bruce H Fireman, Joanne E Schottinger, Virginia P Quinn, Nirupa R Ghai, Theodore R Levin, Charles P Quesenberry
BACKGROUND: The proportion of screening colonoscopic examinations performed by a physician that detect one or more adenomas (the adenoma detection rate) is a recommended quality measure. However, little is known about the association between this rate and patients' risks of a subsequent colorectal cancer (interval cancer) and death. METHODS: Using data from an integrated health care delivery organization, we evaluated the associations between the adenoma detection rate and the risks of colorectal cancer diagnosed 6 months to 10 years after colonoscopy and of cancer-related death...
April 3, 2014: New England Journal of Medicine
https://www.readbyqxmd.com/read/25367179/oncological-outcomes-of-local-excision-compared-with-radical-surgery-after-neoadjuvant-chemoradiotherapy-for-rectal-cancer-a-systematic-review-and-meta-analysis
#4
REVIEW
Irshad Shaikh, Alan Askari, Suzana Ourû, Janindra Warusavitarne, Thanos Athanasiou, Omar Faiz
BACKGROUND: Low rectal cancer is conventionally managed with neoadjuvant chemoradiotherapy (CRT) followed by radical surgery (RS). In patients who refuse a stoma or are unfit for RS, an alternative approach may be the use of pre-op CRT and local excision (LE) where tumours are responsive. The aim of this systematic review is to determine whether differences exist in local recurrence (LR), overall survival (OS) and disease-free (DFS) survival between patients treated with CRT + LE and CRT + RS...
January 2015: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/23414648/computed-tomographic-colonography-versus-barium-enema-for-diagnosis-of-colorectal-cancer-or-large-polyps-in-symptomatic-patients-siggar-a-multicentre-randomised-trial
#5
RANDOMIZED CONTROLLED TRIAL
Steve Halligan, Kate Wooldrage, Edward Dadswell, Ines Kralj-Hans, Christian von Wagner, Rob Edwards, Guiqing Yao, Clive Kay, David Burling, Omar Faiz, Julian Teare, Richard J Lilford, Dion Morton, Jane Wardle, Wendy Atkin
BACKGROUND: Barium enema (BE) is widely available for diagnosis of colorectal cancer despite concerns about its accuracy and acceptability. Computed tomographic colonography (CTC) might be a more sensitive and acceptable alternative. We aimed to compare CTC and BE for diagnosis of colorectal cancer or large polyps in symptomatic patients in clinical practice. METHODS: This pragmatic multicentre randomised trial recruited patients with symptoms suggestive of colorectal cancer from 21 UK hospitals...
April 6, 2013: Lancet
https://www.readbyqxmd.com/read/25255883/false-elevations-of-carcinoembryonic-antigen-levels-are-common-in-patients-under-surveillance-for-colorectal-cancer-recurrence
#6
COMMENT
Mary Kay Barton
No abstract text is available yet for this article.
November 2014: CA: a Cancer Journal for Clinicians
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