Gabriela Hernández-Molina, Gilberto Vargas-Alarcón, Jose M Rodríguez-Pérez, Nancy Martínez-Rodríguez, Guadalupe Lima, Jorge Sánchez-Guerrero
To compare the distribution of HLA-A, B, DRB1 and DQB1 alleles among Mexican patients with primary Sjögren Syndrome (pSS), secondary SS (sSS), connective tissue disease (CTD) without (w/o) SS and historical ethnically healthy controls. We included 28 pSS, 30 sSS, 96 CTD w/o SS patients and 234 controls. HLA-A, B, DRB1 and DQB1 were amplified and sequenced using the Allele SEQR Sequenced Based Typing Kits and analyzed on the ABI Prism*3130 DNA Analyzer using the Assign software. Gene frequencies were obtained by direct counting...
April 2015: Rheumatology International