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Human papillomaviruses (HPV)

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44 papers 25 to 100 followers
By EFRAIN PAEZ Internal Medicine since 1988. Interested in all aspects of Medicine.
https://www.readbyqxmd.com/read/30160386/human-papilloma-virus-hpv-and-genitourinary-cancers-a-narrative-review
#1
Tommaso Cai, Tommaso Di Vico, Jacopo Durante, Alessio Tognarelli, Riccardo Bartoletti
INTRODUCTION: Human papilloma virus (HPV) is the most common sexually transmitted pathogen and its potential role in the genesis of several diseases such as cervical, head and neck, anal and penile cancers, is now largely recognized. Aim of this review article is evaluate and summarize the state of the art of HPV-related uro-genital cancers, focusing on the potentially innovative methods for the diagnosis of infection that should be used to improve viral causative detection and prevent its diffusion through sexual intercourses...
August 29, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29849799/a-rapidly-growing-human-papillomavirus-positive-oral-tongue-squamous-cell-carcinoma-in-a-21-year-old-female-a-case-report
#2
Ebenezer O Appah, Billy Ray Ballard, Michael G Izban, Cassandra Jolin, Philip E Lammers, Dwight D Parrish, Dana R Marshall
Oral tongue squamous cell carcinoma (OTSCC) has a median age at diagnosis of 62 years. The incidence of OTSCC in young adults has been increasing, and the reason is unclear. The present study describes a case, and molecular analysis, of OTSCC in a 21-year-old female. Clinical and pathological information were collected from medical records. Formalin-fixed paraffin-embedded biopsy tissue from the patient was reassessed using standard hematoxylin & eosin staining, and immunohistochemistry was used to assess the expression of cellular p16, MutL homolog (MLH)1, MLH2, MutS homolog 6 (MSH6) and PMS1 homolog 2 (PMS2)...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29914057/human-papilloma-virus-and-autophagy
#3
REVIEW
Domenico Mattoscio, Alessandro Medda, Susanna Chiocca
Human papilloma viruses (HPVs) are a group of double-stranded DNA viruses known to be the primary cause of cervical cancer. In addition, evidence has now established their role in non-melanoma skin cancers, head and neck cancer (HNC), and the development of other anogenital malignancies. The prevalence of HPV-related HNC, in particular oropharyngeal cancers, is rapidly increasing, foreseeing that HPV-positive oropharyngeal cancers will outnumber uterine cervical cancers in the next 15⁻20 years. Therefore, despite the successful advent of vaccines originally licensed for cervical cancer prevention, HPV burden is still very high, and a better understanding of HPV biology is urgently needed...
June 15, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29927817/the-human-papilloma-vaccine-a-time-for-np-leadership
#4
Robin L Hardwicke, Laura J Benjamins, Richard M Grimes
The human papilloma virus (HPV) causes approximately 30,700 annual cancer cases of the cervix, vulva, vagina, penis, oral cavity, and anus. Nurse practitioners can use their unique relationships with patients to advocate for the HPV vaccine. The purpose of this article is to update NPs on current knowledge regarding the HPV vaccine while providing appropriate information necessary for counseling patients and parents.
July 2018: Nurse Practitioner
https://www.readbyqxmd.com/read/29928139/impact-of-multiple-extragenital-warts-on-quality-of-life-in-immune-competent-egyptian-adults-a-comparative-cross-sectional-study
#5
Eman Salah
Background: Extragenital warts (E-GWs) are common benign skin lesions caused by human papilloma virus. Surprisingly, there is no clear data about the impact of multiple E-GWs on quality of life in immune-competent adult patients in comparison to GWs, which have been frequently reported to exhibit a strong negative impact on life quality. Patients and methods: This cross-sectional study investigated the impact of multiple E-GWs on quality of life in immune-competent adults as they are more commonly encountered in daily practice than their genital counterpart in the Egyptian population...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29728850/liquid-based-cytology-do-ancillary-techniques-enhance-detection-of-epithelial-abnormalities
#6
Sridhar Mishra, Nuzhat Husain, Namrata P Awasthi, Yashodhara Pradeep, Roohi Roohi, Sarita Saxena
PURPOSE: Cervical cancer is the fourth most common cancer in women worldwide with very high incidence in India. Liquid-based cytology (LBC) provides the use of ancillary techniques in addition to a good morphology and detection of cytologic abnormalities. The current study was designed to assess the diagnostics of P16INK4a immunoexpression, p16 promoter hypermethylation, human papilloma virus (HPV), and DNA ploidy in LBC samples with cervical precancer and cancer. METHODS: A series of LBC samples categorised by Bethesda system including 22 atypical squamous cells of undetermined significance (ASC-US), 21 low-grade squamous intraepithelial lesion (LSIL), 41 high-grade squamous intraepithelial lesion (HSIL), 54 squamous cell carcinoma (SCC), and 26 controls with normal cytology were included...
July 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29642499/cimetidine-a-safe-treatment-option-for-cutaneous-warts-in-pediatric-heart-transplant-recipients
#7
Bibhuti B Das, Kristin Anton, Nelia Soares, Susan Riojas, Jodi Mcdermott, Leah Knox, Susan Daneman, Bao N Puente
Abstract : Background and Objectives : Immunosuppressed individuals are at particularly increased risk for human papilloma virus-related infections. The primary objective of our study is to determine if there are any adverse effects associated with high-dose cimetidine treatment. A secondary objective is to report our experience with cimetidine in the treatment of cutaneous warts in pediatric heart transplant recipients. Methods and Results : This was a retrospective observational study. A total of 8 pediatric heart transplant recipients diagnosed with multiple recalcitrant warts were the subject of the study...
April 8, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/28450437/solid-lymph-nodes-as-an-imaging-biomarker-for-risk-stratification-in-human-papillomavirus-related-oropharyngeal-squamous-cell-carcinoma
#8
T J Rath, S Narayanan, M A Hughes, R L Ferris, S I Chiosea, B F Branstetter
BACKGROUND AND PURPOSE: Human papillomavirus-related oropharyngeal squamous cell carcinoma is associated with cystic lymph nodes on CT and has a favorable prognosis. A subset of patients with aggressive disease experience treatment failure. Our aim was to determine whether the extent of cystic lymph node burden on staging CT can serve as an imaging biomarker to predict treatment failure in human papillomavirus-related oropharyngeal squamous cell carcinoma. MATERIALS AND METHODS: We identified patients with human papilloma virus-related oropharyngeal squamous cell carcinoma and staging neck CTs...
July 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28466193/efficacy-of-nd-yag-laser-therapy-for-the-treatment-of-verrucae-a-literature-review
#9
REVIEW
Vincent M Hsu, Adam S Aldahan, John P Tsatalis, Marina Perper, Keyvan Nouri
Verrucae are benign epithelial proliferations, characteristically 1-20 mm in diameter, caused by human papilloma virus (HPV) infection occurring on the skin and mucosa (Photomed Laser Surg 33(6):338-42, 2015; Lasers Med Sci 29(3):1111-6, 2014). Prevalence of verrucae is 5-20% in children and young adults with peak incidence reported during teenage years (Lasers Med Sci 29(3):1111-6, 2014; J Am Acad Dermatol 22(4):547-66, 1990; J Korean Med Sci 24(5):889-93, 2009). Patients often express significant displeasure with quality of life due to this cosmetic insecurity, as well as functional problems and physical discomfort when they occur on palms of hands and soles of feet...
July 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28589746/a-review-of-the-use-of-human-papilloma-virus-hpv-in-cervical-screening
#10
B Crossley, J Crossley
Using key words online databases were searched to identify relevant publications to review the use of Human papilloma virus (HPV) in cervical screening. The mode of cervical screening in the UK has been decided but implementation plans have yet to be announced. The protracted uncertainty surrounding the initial announcement to move to HPV primary screening together with the lack of a national steer has resulted in a flight of staff which threatens the provision of the current and future service. The transition will be a challenging time but analysis of data from more than 176,000 women has shown clear evidence of a reduction in the incidence of cancer where HPV testing is used...
July 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28791831/the-role-of-human-papillomavirus-in-oncogenic-transformation-and-its-contribution-to-the-etiology-of-precancerous-lesions-and-cancer-of-the-larynx-a-review
#11
REVIEW
Katarzyna Nowińska, Urszula Ciesielska, Marzenna Podhorska-Okołów, Piotr Dzięgiel
Human papillomavirus (HPV) belongs to the Papillomaviridae family and infects squamous cells and mucous membranes of humans. Various studies conducted over the last years have shown a correlation between HPV infection and carcinogenesis process. The DNA of the virus is detected in approximately 20% of cancers of the upper respiratory tract. The presence of HPV in cancerous lesion of the larynx varies depending on the procedure applied for sample collection and the viral DNA detection method. The high variance in the frequency of HPV detection is observed even among results obtained with the use of PCR reaction...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28888324/a-prize-for-cancer-prevention
#12
Harold Varmus
This year's Lasker-DeBakey Prize for Clinical Research to Douglas Lowy and John Schiller celebrates the science behind one of the greatest advances in the history of cancer research: the development of vaccines that prevent infection and thus prevent tumor induction by pathogenic strains of human papilloma virus (HPV).
September 21, 2017: Cell
https://www.readbyqxmd.com/read/28894500/human-papilloma-virus-hpv-vaccination-questions-and-answers
#13
REVIEW
Allison Mejilla, Emily Li, Cheryl A Sadowski
No abstract text is available yet for this article.
September 2017: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/28926109/role-of-viruses-in-gastrointestinal-cancer
#14
REVIEW
Habibollah Mirzaei, Hossein Goudarzi, Gita Eslami, Ebrahim Faghihloo
Gastrointestinal cancers are a global public health problem, which represent a vast majority of all cancer-caused deaths in both men and women. On the other hand, viral pathogens have been long implicated as etiological factors in the onset of certain human cancers, including gastrointestinal tumors. In this regard, Human Papilloma Virus (HPV), Epstein-Barr Virus (EBV), and John Cunningham Virus (JCV) have been more strongly suggested to be involved in gastrointestinal carcinogenesis; so that, the association of HPV with oropharyngeal and anal cancers and also the association of EBV with gastric cancer have been etiologically confirmed by epidemiological and experimental investigations...
May 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28972438/absence-of-association-between-guillain-barr%C3%A3-syndrome-hospitalizations-and-hpv-vaccine
#15
Geneviève Deceuninck, Chantal Sauvageau, Vladimir Gilca, Nicole Boulianne, Gaston De Serres
BACKGROUND: In 2008, a school-based human papilloma virus (HPV) vaccination program was implemented in the province of Québec. Grade 4 girls (9-10 years old) are routinely vaccinated and grade 9 to 12 girls (14-17 years old) were eligible for the catch-up vaccination. Vaccine coverage of the targeted cohorts was estimated at 76-81%. To assess if HPV vaccination is associated with an increase in GBS hospitalisation, we compared the hospitalization rates of GBS in HPV vaccination targeted and non-targeted groups...
January 2018: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28979164/psychiatric-conditions-and-general-practitioner-attendance-prior-to-hpv-vaccination-and-the-risk-of-referral-to-a-specialized-hospital-setting-because-of-suspected-adverse-events-following-hpv-vaccination-a-register-based-matched-case-control-study
#16
Tina Hovgaard Lützen, Bodil Hammer Bech, Jesper Mehlsen, Claus Høstrup Vestergaard, Lene Wulff Krogsgaard, Jørn Olsen, Mogens Vestergaard, Oleguer Plana-Ripoll, Dorte Rytter
AIM: No association between human papilloma virus (HPV) vaccination and numerous diseases has been found. Still, a large number of Danish women are reporting suspected adverse events. Other factors may play a role, and the aim of this study is to examine the association between psychiatric conditions, general practitioner (GP) attendance and indicators of psychological symptoms prior to HPV vaccination and the risk of referral to an HPV center following vaccination. STUDY DESIGN AND SETTING: Register-based, matched case-control study...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28632148/claw-foot-a-case-report
#17
REVIEW
Alessandro Innocenti, Francesco Ciancio, Cecilia Taverna, Sara Tanini, Aurelio Portincasa, Domenico Parisi, Marco Innocenti, Vincenzo De Giorgi
A cutaneous horn could be defined as a conical projection on the surface of skin made of cornified material and resembling an animal horn. These lesions most commonly affect light-skinned men aged between 50 to 89 years and usually appear in sun exposed areas. Radiation, chronic irritation and even human papilloma virus-2 infection may be precipitating factors. More than half of the cases originate from either malignant or premalignant lesions, therefore the base of the lesion must be carefully examined histologically...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/25859081/hpv-vaccine-current-status-and-future-directions
#18
REVIEW
Sushil Kumar, Manash Biswas, Tony Jose
HPV Vaccine was introduced to prevent cervical cancer known to be caused by infection with one or more of the high risk subtypes of the Human papilloma virus (HPV). Since introduction, trials have proven its efficacy in preventing Cervical intraepithelial neoplasia (CIN) beyond doubt and its effectiveness in preventing cervical cancer though presumptive is reasonably certain as per mathematical modelling. It also prevents other HPV related anogenital and oropharyngeal malignancies in both sexes. HPV vaccines have courted many controversies related to its efficacy, safety, ideal age of vaccination, use in HPV infected individuals and use in males...
April 2015: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/25872549/suspected-side-effects-to-the-quadrivalent-human-papilloma-vaccine
#19
Louise Brinth, Ann Cathrine Theibel, Kirsten Pors, Jesper Mehlsen
INTRODUCTION: The quadrivalent vaccine that protects against human papilloma virus types 6, 11, 16 and 18 (Q-HPV vaccine, Gardasil) was included into the Danish childhood vaccination programme in 2009. During the past years, a collection of symptoms primarily consistent with sympathetic nervous system dysfunction have been described as suspected side effects to the Q-HPV vaccine. METHODS: We present a description of suspected side effects to the Q-HPV vaccine in 53 patients referred to our Syncope Unit for tilt table test and evaluation of autonomic nervous system function...
April 2015: Danish Medical Journal
https://www.readbyqxmd.com/read/25883161/review-of-in-situ-and-invasive-penile-squamous-cell-carcinoma-and-associated-non-neoplastic-dermatological-conditions
#20
REVIEW
Michelle R Downes
Penile carcinoma is a rare genitourinary malignancy in North America and Europe with highest rates recorded in South America, Africa and Asia. Recent classifications have refined the terminology used in classifying intraepithelial/in situ lesions and additionally newer entities have been recognised in the invasive category. While increasing recognition of a bimodal pathway of penile carcinogenesis has facilitated understanding and classification of these tumours, handling and subtyping of penile malignancies presents a challenge to the reporting pathologist, in part due to their rarity...
May 2015: Journal of Clinical Pathology
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