collection
MENU ▼
Read by QxMD icon Read
search

Neurosarcoidosis

shared collection
95 papers 25 to 100 followers
By EFRAIN PAEZ Internal Medicine since 1988. Interested in all aspects of Medicine.
https://www.readbyqxmd.com/read/28975003/nodular-leptomeningeal-enhancement-in-neurosarcoidosis-before-and-after-treatment
#1
J David Avila, Robert C Bucelli
No abstract text is available yet for this article.
October 2017: Neurohospitalist
https://www.readbyqxmd.com/read/29030454/infliximab-for-the-treatment-of-cns-sarcoidosis-a-multi-institutional-series
#2
Jeffrey M Gelfand, Michael J Bradshaw, Barney J Stern, David B Clifford, Yunxia Wang, Tracey A Cho, Laura L Koth, Stephen L Hauser, Jason Dierkhising, NgocHanh Vu, Subramaniam Sriram, Harold Moses, Francesca Bagnato, Jeffrey A Kaufmann, Deidre J Ammah, Tsion H Yohannes, Mark J Hamblin, Nagagopal Venna, Ari J Green, Siddharama Pawate
OBJECTIVE: To describe clinical and imaging responses in neurosarcoidosis to infliximab, a monoclonal antibody against tumor necrosis factor-α. METHODS: Investigators at 6 US centers retrospectively identified patients with CNS sarcoidosis treated with infliximab, including only patients with definite or probable neurosarcoidosis following rigorous exclusion of other causes. RESULTS: Of 66 patients with CNS sarcoidosis (27 definite, 39 probable) treated with infliximab for a median of 1...
November 14, 2017: Neurology
https://www.readbyqxmd.com/read/29061245/neurosarcoidosis
#3
REVIEW
Patompong Ungprasert, Eric L Matteson
Neurosarcoidosis occurs in 3% to 10% of patients with sarcoidosis. Cranial neuropathy and meningeal involvement are the most common manifestations, but any part of the nervous system can be affected. Definite diagnosis requires the presence of noncaseating granuloma in the nervous system, although histopathologic confirmation is often not obtainable. Moderate to high dose of glucocorticoids is the main therapy for neurosarcoidosis. Relapse often occurs after the dose of glucocorticoids is tapered down, often necessitating the use of steroid-sparing immunosuppressive agents...
November 2017: Rheumatic Diseases Clinics of North America
https://www.readbyqxmd.com/read/29052731/demystifying-neurosarcoidosis-and-informing-prognosis
#4
Jeffrey M Gelfand
No abstract text is available yet for this article.
November 1, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29052709/association-of-prognostic-factors-and-immunosuppressive-treatment-with-long-term-outcomes-in-neurosarcoidosis
#5
Bastien Joubert, Catherine Chapelon-Abric, Lucie Biard, David Saadoun, Sophie Demeret, Didier Dormont, Matthieu Resche-Rigon, Patrice Cacoub
Importance: Prognostic factors are lacking in neurosarcoidosis (NS), and the association of immunosuppressive treatments with outcomes are unclear. Objectives: To identify prognostic factors of and analyze the association of immunosuppressive treatment with relapse of NS. Design, Setting, and Participants: In this retrospective study, a cohort of 234 patients fulfilled the diagnostic criteria for NS in a tertiary referral center in Paris, France, from January 1, 1990, through December 31, 2015...
November 1, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28856748/propionibacterium-acnes-associated-neurosarcoidosis-a-case-report-with-review-of-the-literature
#6
Guang Yang, Yoshinobu Eishi, Anwar Raza, Heather Rojas, Adina Achiriloaie, Kenneth De Los Reyes, Ravi Raghavan
A 56-year-old woman with a 3-year history of hydrocephalus and ventriculo-peritoneal shunt placement, presented with worsening altered level of consciousness for 2 days. Imaging studies showed severe ventriculomegaly involving the lateral and third ventricles with multiple septated cysts noted in the lateral ventricles predominantly near the frontal horns. Histopathologic examination of the excised brain lesion revealed choroid plexus tissue and adjacent cerebral parenchyma with several non-caseating granulomas...
August 30, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/28751284/search-for-biomarkers-of-neurosarcoidosis-by-proteomic-analysis-of-cerebrospinal-fluid
#7
Ludmia Taibi, Céline Boursier, Gilles Clodic, Gérard Bolbach, Bénédicte Bénéteau-Burnat, Michel Vaubourdolle, Bruno Baudin
Sarcoidosis is a systemic granulomatous disease, which mostly affects lung. Central nervous system can be affected causing a neurosarcoidosis in 5 to 15% of all sarcoidosis patients. The definitive diagnosis is established on histological examination of brain granulomas. Angiotensin converting enzyme is currently the most relevant biomarker to confirm a probable diagnosis; however, it lacks sensitivity and specificity. We aim to find novel biomarkers of neurosarcoidosis in cerebrospinal fluid (CSF) by proteomic analysis, combining two-dimension electrophoresis (2-DE) and mass spectrometry...
August 1, 2017: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/28750463/neurosarcoidosis
#8
Daniel A Culver, Manuel L Ribeiro Neto, Brandon P Moss, Mary A Willis
No abstract text is available yet for this article.
August 2017: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28716286/neurosarcoidosis-according-to-zajicek-and-scolding-criteria-15-probable-and-definite-cases-their-treatment-and-outcomes
#9
Gonçalo Cação, Ana Branco, Mariana Meireles, José Eduardo Alves, Andrea Mateus, Ana Martins Silva, Ernestina Santos
INTRODUCTION: Neurosarcoidosis occurs in about 5% to 15% of patients with sarcoidosis. The purpose of this study was to identify and characterize a cohort of neurosarcoidosis patients and to review the largest previously reported neurosarcoidosis case series. METHODS: This retrospective study enrolled all patients with the diagnosis of probable or definitive neurosarcoidosis according to Zajicek and Scolding criteria, followed at the neurology department of a tertiary center in Portugal from January 1989 to December 2015...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28761540/neurosarcoidosis-presenting-as-an-incidental-solitary-cranial-ring-enhancing-lesion
#10
Michael Thambuswamy, Ashish H Shah, Mai Tran, Joanne T Thambuswamy, Amade Bregy, Michael D Norenberg, Ricardo J Komotar
Isolated neurosarcoidosis without prior systemic symptoms is extremely rare, occurring in approximately 2% of patients with neurosarcoidosis. Due to its rarity, mistakes in diagnosis and treatment occur commonly. We present a case of a 47-year-old female who was found to have an incidentally discovered solitary intracranial lesion that mimicked a high-grade neoplasm, but was later confirmed to be neurosarcoidosis. Incidental solitary neurosarcoid granulomas are difficult to diagnose due to its nonspecific clinical and imaging presentations...
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28749553/myelopathy-in-beh%C3%A3-et-s-disease-the-bagel-sign
#11
Ugur Uygunoglu, Burcu Zeydan, Yesim Ozguler, Serdal Ugurlu, Emire Seyahi, Naci Kocer, Civan Islak, Kejal Kantarci, Sabahattin Saip, Aksel Siva, Orhun H Kantarci
OBJECTIVE: To describe the clinical and distinctive imaging features of myelopathy associated with Behçet's disease (BD). METHODS: We evaluated the records of patients meeting the following criteria: (1) fulfillment of the International Study Group criteria for BD; (2) clinically suggestive of myelopathy; (3) simultaneous spinal cord and brain magnetic resonance images (MRIs) within 1 month of acute worsening of myelopathy; and (4) follow-up duration ≥ 1 year after initial MRI evaluation...
August 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28598872/many-faces-of-neurosarcoidosis-from-chronic-meningitis-to-myelopathy
#12
Daan Fritz, Mareye Voortman, Diederik van de Beek, Marjolein Drent, Matthijs C Brouwer
PURPOSE OF REVIEW: Neurosarcoidosis occurs in 5% of patients with sarcoidosis and can be difficult to diagnose. In this review we discuss the most recent advances in our understanding of the disease, describing clinical characteristics, diagnostic process, treatment, and prognosis. RECENT FINDINGS: Clinical presentation is heterogeneous with most patients presenting with cranial nerve palsy, headache, or sensory abnormalities. Patients are classified according to probability of the diagnosis with the Zajicek criteria...
September 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28601860/characteristics-and-long-term-outcome-of-neurosarcoidosis-a-population-based-study-from-1976-2013
#13
Patompong Ungprasert, Cynthia S Crowson, Eric L Matteson
BACKGROUND/AIMS: Neurosarcoidosis is a rare condition with serious health consequences. However, little is known about clinical characteristics and outcome of neurosarcoidosis in the community setting. METHODS: Patients with neurosarcoidosis were identified from a previously described cohort of patients with incident sarcoidosis from Olmsted County, Minnesota, United States from 1976 to 2013 using individual medical record review. Data on clinical characteristics, treatment, and outcome were collected...
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28526323/-18-f-fdg-pet-ct-helps-in-unmasking-the-great-mimicker-a-case-of-neurosarcoidosis-with-isolated-involvement-of-the-spinal-cord
#14
A Gholamrezanezhad, L Mehta
A 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The (18)F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord, as well as a mildly hypermetabolic bilateral hilar lymphadenopathy and a mildly hypermetabolic pulmonary nodule, suggestive of sarcoidosis versus metastasis...
May 16, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28484206/a-rare-case-of-neurosarcoidosis-presenting-as-severe-hypothermia
#15
Ribhi Hazin, Diana Saed, Mohammed Salem, Mohamed Zeyara, Mohammed Omar Subei
BACKGROUND Sarcoidosis is a systemic disease of unclear etiology with an estimated prevalence of 10 cases per 100,000 population. Although sarcoidosis primarily affects the pulmonary system, it affects the nervous system in 5-10% of patients with the condition. CASE REPORT This article describes a case of neurosarcoidosis with the primary presenting finding of hypothermia. A 41-year-old African-American man with a past medical history significant for hypertension, asthma, and anemia, presented to the Emergency Department after being found unresponsive at home...
May 9, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28389310/leptomeningeal-infiltration-the-hallmark-of-neurosarcoidosis
#16
Hafid Ait-Oufella, Caroline Gabignon, Jean Capron, Arsene Mekinian
No abstract text is available yet for this article.
August 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28400903/neurosarcoidosis-presenting-with-recurrent-strokes-a-case-report-and-literature-review
#17
Naheed Raza, Karisa C Schreck
Neurosarcoidosis is a rare but important cause of stroke as it is treatable. Cases reported thus far have primarily been in young people who are relatively healthy. Here we report the case of a 73-year-old woman presenting with recurrent strokes and high-grade intracranial stenosis caused by probable neurosarcoidosis. This is unique as neurosarcoidosis is not usually considered as an etiology for recurrent strokes in our patient's age-group. We review and categorize published cases of neurosarcoidosis causing stroke and describe a classification scheme for certainty of diagnosis...
April 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28186582/neurosarcoidosis-leptomeninigeal-cavernous-sinus-and-pituitary-involvement
#18
L Bicart-Sée, M Roriz, H Chabriat, F Buffon-Porcher, E Cognat
No abstract text is available yet for this article.
June 1, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28260120/long-term-outcomes-of-refractory-neurosarcoidosis-treated-with-infliximab
#19
Fleur Cohen Aubart, Diane Bouvry, Damien Galanaud, Caroline Dehais, Guillaume Mathey, Dimitri Psimaras, Julien Haroche, Corinne Pottier, Miguel Hie, Alexis Mathian, Hervé Devilliers, Hilario Nunes, Dominique Valeyre, Zahir Amoura
Central nervous system localizations of sarcoidosis may be refractory to conventional treatment such as steroids and immunosuppressive drugs. Infliximab, a TNF-α antagonist chimeric antibody, has been shown to be effective for treatment of these localizations. The aim of this study was to evaluate the efficacy and safety, in particular the long-term outcomes, of the use of infliximab for the treatment of neurosarcoidosis. We retrospectively reviewed medical records of patients with neurosarcoidosis who had been treated with infliximab between 2009 and 2015...
May 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28219645/-18-f-fdg-pet-ct-guiding-to-diagnosis-of-neurosarcoidosis
#20
P Guglielmo, C Crivellaro, L Marzorati, M Patassini, S Morzenti, C Landoni
No abstract text is available yet for this article.
July 2017: Revista Española de Medicina Nuclear e Imagen Molecular
label_collection
label_collection
3040
1
2
2017-03-11 15:05:26
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"