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Postoperative nausea & vomiting (PONV)

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2 papers 0 to 25 followers
By Scott Bentley General Practitioner / GP Anaesthetist in Australia.
Philip J Peyton, Christine Yx Wu
BACKGROUND: Inclusion of nitrous oxide in the gas mixture has been implicated in postoperative nausea and vomiting (PONV) in numerous studies. However, these studies have not examined whether duration of exposure was a significant covariate. This distinction might affect the future place of nitrous oxide in clinical practice. METHODS: PubMed listed journals reporting trials in which patients randomized to a nitrous oxide or nitrous oxide-free anesthetic for surgery were included, where the incidence of PONV within the first 24 postoperative hours and mean duration of anesthesia was reported...
May 2014: Anesthesiology
Christian C Apfel, Alparslan Turan, Kimberly Souza, Joseph Pergolizzi, Cyrill Hornuss
Opioids are a key risk factor for postoperative nausea and vomiting (PONV). As intravenous (i.v.) acetaminophen reduces postoperative pain and opioid requirements, one would expect i.v. acetaminophen to be associated with a lower incidence of opioid-induced side effects, including PONV. We conducted a systematic search using Medline and Cochrane databases supplemented with hand search of abstract proceedings to identify randomized-controlled trials of i.v. acetaminophen. Inclusion criteria were (a) randomized for i...
May 2013: Pain
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