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By Caroline Rao MD
Hien T Tran, Robert A Lee, Gagik Oganesyan, S Brian Jiang
BACKGROUND AND OBJECTIVE: Non-melanoma skin cancers are the most common cause of cancer worldwide. Within this grouping, the most common skin cancer is basal cell carcinoma (BCC) followed by squamous cell carcinoma (SCC). Recent evidence has shown that BCCs can be cleared by a pulsed-dye laser after multiple treatments using a single pass setting. Given the necessity for multiple treatments in the prior studies, we sought to determine whether tumor clearance could instead be achieved using a single treatment of the pulsed-dye laser in a stacked pulse setting...
August 2012: Lasers in Surgery and Medicine
Eleni Linos, Steven A Schroeder, Mary-Margaret Chren
No abstract text is available yet for this article.
September 10, 2014: JAMA: the Journal of the American Medical Association
S Karsai, H Friedl, H Buhck, M Jünger, M Podda
BACKGROUND: Pulsed dye laser (PDL) treatments have been suggested to be a safe and effective therapeutic approach for treating basal cell carcinomas (BCCs). However, robust supporting evidence is lacking due to inconsistent design of available studies. OBJECTIVES: To evaluate PDL efficacy and safety in treating superficial BCC (sBCC) at low-risk anatomical sites in an evidence-based study setting. MATERIALS AND METHODS: Thirty-nine patients (27 men and 12 women, 75·9 ± 10 years) with a total of 100 sBCCs were randomized to receive PDL treatment (wavelength 595 nm; fluence 8 J cm(-2) ; pulse duration 0·5 ms; spot size 10 mm) or sham treatment...
March 2015: British Journal of Dermatology
Aimée H M M Arits, Klara Mosterd, Brigitte Ab Essers, Eefje Spoorenberg, Anja Sommer, Michette J M De Rooij, Han P A van Pelt, Patricia J F Quaedvlieg, Gertruud A M Krekels, Pierre A F A van Neer, Joris J Rijzewijk, Adrienne J van Geest, Peter M Steijlen, Patty J Nelemans, Nicole W J Kelleners-Smeets
BACKGROUND: Superficial basal-cell carcinoma is most commonly treated with topical non-surgical treatments, such as photodynamic therapy or topical creams. Photodynamic therapy is considered the preferable treatment, although this has not been previously tested in a randomised control trial. We assessed the effectiveness of photodynamic therapy compared with imiquimod or fluorouracil in patients with superficial basal-cell carcinoma. METHODS: In this single blind, non-inferiority, randomised controlled multicentre trial, we enrolled patients with a histologically proven superficial basal-cell carcinoma at seven hospitals in the Netherlands...
June 2013: Lancet Oncology
Mary Alice Mina, Anthony Picariello, Jessica L Fewkes
BACKGROUND: Superficial basal cell carcinomas (BCC) are often considered a non-aggressive form of skin cancer, most often found on the trunk in younger patients. OBJECTIVE: To determine the characteristics of superficial BCC of the head and neck. MATERIALS AND METHODS: A retrospective review of patients undergoing Mohs micrographic surgery (MMS) for the treatment of a purely superficial BCC on the head and neck region was performed. RESULTS: Superficial BCC occurred more commonly in women (66...
July 2013: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
A Altman, T Rosen, J A Tschen, T Hoffmann, S Bruce, D M Siegel, M L Levy, D Schaefer, L H Goldberg
The occurrence of cutaneous carcinoma in black patients is an unusual phenomenon, with basal cell carcinoma being particularly uncommon. We present five cases of basal cell epithelioma in black patients collected from the Texas Medical Center to graphically illustrate the varied and often atypical clinical presentations of such tumors. This report supports recent series of basal cell epithelioma in black patients derived from retrospective chart reviews.
November 1987: Journal of the American Academy of Dermatology
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