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Substance Use Disorders

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181 papers 500 to 1000 followers Substance Related and Addictive Disorders
By Edwin Kim Resident Physician, Aspiring Addiction Psychiatrist
Samuel J House, Jessica L Coker, Zachary N Stowe
No abstract text is available yet for this article.
November 1, 2016: American Journal of Psychiatry
Roger D Weiss, Jennifer Sharpe Potter, Scott E Provost, Zhen Huang, Petra Jacobs, Albert Hasson, Robert Lindblad, Hilary Smith Connery, Kristi Prather, Walter Ling
The National Institute on Drug Abuse Clinical Trials Network launched the Prescription Opioid Addiction Treatment Study (POATS) in response to rising rates of prescription opioid dependence and gaps in understanding the optimal course of treatment for this population. POATS employed a multi-site, two-phase adaptive, sequential treatment design to approximate clinical practice. The study took place at 10 community treatment programs around the United States. Participants included men and women age > or =18 who met Diagnostic and Statistical Manual, 4th Edition criteria for dependence upon prescription opioids, with physiologic features; those with a prominent history of heroin use (according to pre-specified criteria) were excluded...
March 2010: Contemporary Clinical Trials
Karma McKelvey, Johannes Thrul, Danielle Ramo
BACKGROUND: Historically, smoking cessation was thought to negatively impact substance use outcomes among smokers who use other substances. We sought to synthesize recent reports on this association. METHODS: Google Scholar, PubMed, and Cinahl were searched for studies published from 2006 to March 29, 2016 that reported impact of smoking cessation treatment or quitting smoking on substance use or substance use disorder treatment outcomes in the general population and among those in substance abuse treatment...
February 2017: Addictive Behaviors
Deborah S Hasin, Bradley T Kerridge, Tulshi D Saha, Boji Huang, Roger Pickering, Sharon M Smith, Jeesun Jung, Haitao Zhang, Bridget F Grant
OBJECTIVE: Attitudes toward marijuana are changing, the prevalence of DSM-IV cannabis use disorder has increased, and DSM-5 modified the cannabis use disorder criteria. Therefore, updated information is needed on the prevalence, demographic characteristics, psychiatric comorbidity, disability, and treatment for DSM-5 cannabis use disorder. METHOD: In 2012-2013, 36,309 participants ≥18 years old were interviewed in the National Epidemiologic Survey on Alcohol and Related Conditions-III...
June 1, 2016: American Journal of Psychiatry
Judson A Brewer, Sarah Bowen, Joseph T Smith, G Alan Marlatt, Marc N Potenza
Both depression and substance use disorders represent major global public health concerns and are often co-occurring. Although there are ongoing discoveries regarding the pathophysiology and treatment of each condition, common mechanisms and effective treatments for co-occurring depression and substance abuse remain elusive. Mindfulness training has been shown recently to benefit both depression and substance use disorders, suggesting that this approach may target common behavioral and neurobiological processes...
October 2010: Addiction
Joanna M Robinson, Benjamin O Ladd, Kristen G Anderson
The emotion-based domains of impulsivity, positive and negative urgency, are facets that have garnered attention due to their associations with substance use, and mindfulness based strategies have shown promise in reducing substance use in adults. The aim of the current study was to examine relations among urgency, mindfulness, and substance use in adolescence. Cross-sectional data were collected from students (N=1,051) at a large, private high school in the Pacific Northwest. Both positive and negative urgency were uniquely associated with greater likelihood of lifetime and current alcohol use; only positive urgency predicted lifetime marijuana use...
June 2014: Addictive Behaviors
Kenny A Karyadi, J Davis VanderVeen, Melissa A Cyders
BACKGROUND: The relationship between trait mindfulness and substance use behaviors has been inconsistent across studies. The current meta-analysis aimed at quantifying the magnitude of this relationship, and at determining how this relationship varies in context of (1) mindfulness facets, (2) substance type, (3) sample characteristics, and (4) substance use severity. METHODS: Using electronic databases, the literature search yielded 303 articles, but only 39 articles met inclusion criteria to be included in this meta-analysis...
October 1, 2014: Drug and Alcohol Dependence
Annabelle K Simpson, Viktoriya Magid
Cannabis use in the adolescent population poses a significant threat of addiction potential resulting in altered neurodevelopment. There are multiple mechanisms of treatment of cannabis use disorder including behavioral therapy management and emerging data on treatment via pharmacotherapy. Recognizing the diagnostic criteria for cannabis use disorder, cannabis withdrawal syndrome, and mitigating factors that influence adolescent engagement in cannabis use allows for comprehensive assessment and management in the adolescent population...
July 2016: Child and Adolescent Psychiatric Clinics of North America
George F Koob, Nora D Volkow
Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by a combination of exaggerated incentive salience and habit formation, reward deficits and stress surfeits, and compromised executive function in three stages. The rewarding effects of drugs of abuse, development of incentive salience, and development of drug-seeking habits in the binge/intoxication stage involve changes in dopamine and opioid peptides in the basal ganglia. The increases in negative emotional states and dysphoric and stress-like responses in the withdrawal/negative affect stage involve decreases in the function of the dopamine component of the reward system and recruitment of brain stress neurotransmitters, such as corticotropin-releasing factor and dynorphin, in the neurocircuitry of the extended amygdala...
August 2016: Lancet Psychiatry
David E Marcovitz, R Kathryn McHugh, Julie Volpe, Victoria Votaw, Hilary S Connery
BACKGROUND AND OBJECTIVES: Identifying predictors of early drop out from outpatient treatment of opioid use disorder (OUD) with buprenorphine/naloxone (BN) may improve care for subgroups requiring more intensive engagement to achieve stabilization. However, previous research on predictors of dropout among this population has yielded mixed results. The aim of the present study was to elucidate these mixed findings by simultaneously evaluating a range of putative risk factors that may predict dropout in BN maintenance treatment...
September 2016: American Journal on Addictions
Ghita Dadi, Alain Dervaux, Marie-Odile Krebs, Raphaël Gaillard, Xavier Laqueille, Marion Plaze
No abstract text is available yet for this article.
August 1, 2016: American Journal of Psychiatry
Marc A Schuckit
This article provides an overview of the current treatment of opioid-related conditions, including treatments provided by general practitioners and by specialists in substance-use disorders. The recent dramatic increase in misuse of prescription analgesics, the easy accessibility of opioids such as..
July 28, 2016: New England Journal of Medicine
Steven A Schroeder, Kenneth E Warner
No abstract text is available yet for this article.
July 15, 2010: New England Journal of Medicine
Steven A Schroeder
No abstract text is available yet for this article.
June 2016: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Steven A Schroeder
Smoking among patients with mental illness is a major and underappreciated public health problem. The case of Ms G, a 51-year-old woman with bipolar disorder who wishes to quit smoking, illustrates the importance and feasibility of smoking cessation in patients with psychiatric disorders. Persons with chronic mental illness and/or substance abuse constitute 22% of the US population yet are estimated to consume 44% of cigarettes. As many as 200,000 of the 435,000 annual deaths related to smoking in the United States are estimated to occur in this population...
February 4, 2009: JAMA: the Journal of the American Medical Association
Steven A Schroeder
Everyone knows cigarette smoking is bad for you. Most people in the United States assume that smoking is on its way out. But the grim reality is that smoking still exerts an enormous toll on the health of Americans, as documented in two articles in this issue of the Journal. Both articles review..
January 24, 2013: New England Journal of Medicine
Michael C Fiore, Steven A Schroeder, Timothy B Baker
January 2014 marks the 50th anniversary of the landmark Smoking and Health: Report of the Advisory Committee to the Surgeon General of the Public Health Service — an important moment to take stock of efforts to eliminate the harms of tobacco use. Smoking rates in the United States have decreased..
January 23, 2014: New England Journal of Medicine
Lekshmi Santhosh, Margaret Meriwether, Catherine Saucedo, Reason Reyes, Christine Cheng, Brian Clark, Doug Tipperman, Steven A Schroeder
Smoking is a major contributor to premature mortality among people with mental illness and substance abuse. Historically, the Substance Abuse and Mental Health Services Administration (SAMHSA) did not include smoking cessation in its mission. We describe the development of a unique partnership between SAMHSA and the University of California, San Francisco's Smoking Cessation Leadership Center. Starting with an educational summit in Virginia in 2007, it progressed to a jointly sponsored "100 Pioneers for Smoking Cessation" campaign that provided grants and technical assistance to organizations promoting cessation...
May 2014: American Journal of Public Health
Steven A Schroeder, Chad D Morris
Tobacco use exerts a huge toll on persons with mental illnesses and substance abuse disorders, accounting for 200,000 of the annual 443,000 annual tobacco-related deaths in the United States. Persons with chronic mental illness die 25 years earlier than the general population does, and smoking is the major contributor to that premature mortality. This population consumes 44% of all cigarettes, reflecting very high prevalence rates plus heavy smoking by users. The pattern reflects a combination of biological, psychosocial, cultural, and tobacco industry-related factors...
2010: Annual Review of Public Health
Anita Ram, Margaret S Chisolm
This commentary highlights the growing demand for substance abuse prevention and treatment, summarizes the literature regarding the current insufficiencies in substance abuse training in medical schools, and suggests strategies to address this gap in physician education. The authors describe how the combination of mandated coverage for substance abuse services and expanding treatment needs means that more physicians, regardless of their patient populations, will be faced with addressing the problem of substance use...
June 2016: Academic Psychiatry
2016-07-21 22:00:12
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