collection
https://read.qxmd.com/read/26068897/fluid-therapy-in-2015-and-beyond-the-mini-fluid-challenge-and-mini-fluid-bolus-approach
#21
EDITORIAL
P E Marik
No abstract text is available yet for this article.
September 2015: British Journal of Anaesthesia
https://read.qxmd.com/read/25897036/defining-normal-heart-and-respiratory-rates-in-children
#22
EDITORIAL
Roger C Parslow
No abstract text is available yet for this article.
August 2015: Archives of Disease in Childhood
https://read.qxmd.com/read/25825534/screening-and-routine-supplementation-for-iron-deficiency-anemia-a-systematic-review
#23
REVIEW
Marian S McDonagh, Ian Blazina, Tracy Dana, Amy Cantor, Christina Bougatsos
BACKGROUND AND OBJECTIVES: Supplementation and screening for iron-deficiency anemia (IDA) in young children may improve growth and development outcomes. The goal of this study was to review the evidence regarding the benefits and harms of screening and routine supplementation for IDA for the US Preventive Services Task Force. METHODS: We searched Medline and Cochrane databases (1996-August 2014), as well as reference lists of relevant systematic reviews. We included trials and controlled observational studies regarding the effectiveness and harms of routine iron supplementation and screening in children ages 6 to 24 months conducted in developed countries...
April 2015: Pediatrics
https://read.qxmd.com/read/25635586/developmental-origins-of-health-and-disease-a-paradigm-for-understanding-disease-cause-and-prevention
#24
REVIEW
Jerrold J Heindel, Laura N Vandenberg
PURPOSE OF REVIEW: Although diseases may appear clinically throughout the lifespan, it is clear that many diseases have origins during development. Altered nutrition, as well as exposure to environmental chemicals, drugs, infections, or stress during specific times of development, can lead to functional changes in tissues, predisposing those tissues to diseases that manifest later in life. This review will focus on the role of altered nutrition and exposures to environmental chemicals during development in the role of disease and dysfunction...
April 2015: Current Opinion in Pediatrics
https://read.qxmd.com/read/25689454/therapeutic-hypothermia-for-neonatal-encephalopathy
#25
REVIEW
Seetha Shankaran
PURPOSE OF REVIEW: Hypothermia for neonatal encephalopathy is now the standard of care. The purpose of this review is to evaluate recent publications (during the past 18 months) that impact the practice of hypothermia as neuroprotection for neonatal hypoxic-ischemic encephalopathy. RECENT FINDINGS: The review will examine recent publications that influence clinical care, including committee opinion, meta-analysis, and reports of how this practice has evolved in the clinical arena...
April 2015: Current Opinion in Pediatrics
https://read.qxmd.com/read/25689456/what-is-new-for-patent-ductus-arteriosus-management-in-premature-infants-in-2015
#26
REVIEW
Krystle M Perez, Matthew M Laughon
PURPOSE OF REVIEW: A patent ductus arteriosus (PDA) in premature infants is common and is associated with a number of adverse outcomes. The purpose of this review is to discuss recent literature in PDA diagnosis and management. RECENT FINDINGS: The diagnosis of a 'hemodynamically significant' PDA is challenging and a robust definition is lacking. The risks and benefits of therapies, either medical or surgical, designed to close the PDA, are controversial. Oral acetaminophen has gained increasing attention as an alternative pharmaceutical agent for PDA closure in premature infants, although safety concerns remain...
April 2015: Current Opinion in Pediatrics
https://read.qxmd.com/read/23782686/retinopathy-of-prematurity
#27
REVIEW
Ann Hellström, Lois E H Smith, Olaf Dammann
The immature retinas of preterm neonates are susceptible to insults that disrupt neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors due to hyperoxia and loss of the maternal-fetal interaction result in an arrest of retinal vascularisation (phase 1). Subsequently, the increasingly metabolically active, yet poorly vascularised, retina becomes hypoxic, stimulating growth factor-induced vasoproliferation (phase 2), which can cause retinal detachment. In very premature infants, controlled oxygen administration reduces but does not eliminate retinopathy of prematurity...
October 26, 2013: Lancet
https://read.qxmd.com/read/25751673/comparison-of-isotonic-and-hypotonic-intravenous-maintenance-fluids-a-randomized-clinical-trial
#28
RANDOMIZED CONTROLLED TRIAL
Jeremy N Friedman, Carolyn E Beck, Julie DeGroot, Denis F Geary, Daniel J Sklansky, Stephen B Freedman
IMPORTANCE: Use of hypotonic intravenous fluids for maintenance requirements is associated with increased risk of hyponatremia that results in morbidity and mortality in children. Clinical trial data comparing isotonic and hypotonic maintenance fluids in nonsurgical hospitalized pediatric patients outside intensive care units are lacking. OBJECTIVE: To compare isotonic (sodium chloride, 0.9%, and dextrose, 5%) with hypotonic (sodium chloride, 0.45%, and dextrose, 5%) intravenous maintenance fluids in a hospitalized general pediatric population...
May 2015: JAMA Pediatrics
https://read.qxmd.com/read/25667239/nonpharmacologic-treatment-of-functional-abdominal-pain-disorders-a-systematic-review
#29
REVIEW
Juliette M T M Rutten, Judith J Korterink, Leonie M A J Venmans, Marc A Benninga, Merit M Tabbers
BACKGROUND AND OBJECTIVE: Various nonpharmacologic treatments are available for pediatric abdominal pain-related functional gastrointestinal disorders (AP-FGIDs). Data on efficacy and safety are scarce. The goal of this study was to summarize the evidence regarding nonpharmacologic interventions for pediatric AP-FGIDs: lifestyle interventions, dietary interventions, behavioral interventions, prebiotics and probiotics, and alternative medicine. METHODS: Searches were conducted of the Medline and Cochrane Library databases...
March 2015: Pediatrics
https://read.qxmd.com/read/25565573/considerations-and-intervention-in-congenital-muscular-torticollis
#30
REVIEW
Maureen C Suhr, Magdalena Oledzka
PURPOSE OF REVIEW: To present the current literature regarding congenital muscular torticollis (CMT) to promote the most effective and evidence-based intervention. CMT is a musculoskeletal deformity observed at birth or in infancy, characterized by persistent head tilt toward the ipsilateral side with the chin rotated toward the contralateral side. The incidence of torticollis is on the rise and as a result there has been a surge in the literature on the topic, however, until recently, there was little consensus on the treatment approach...
February 2015: Current Opinion in Pediatrics
https://read.qxmd.com/read/25472864/140-mmol-l-of-sodium-versus-77-mmol-l-of-sodium-in-maintenance-intravenous-fluid-therapy-for-children-in-hospital-pims-a-randomised-controlled-double-blind-trial
#31
RANDOMIZED CONTROLLED TRIAL
Sarah McNab, Trevor Duke, Mike South, Franz E Babl, Katherine J Lee, Sarah J Arnup, Simon Young, Hannah Turner, Andrew Davidson
BACKGROUND: Use of hypotonic intravenous fluid to maintain hydration in children in hospital has been associated with hyponatraemia, leading to neurological morbidity and mortality. We aimed to assess whether use of fluid solutions with a higher sodium concentration reduced the risk of hyponatraemia compared with use of hypotonic solutions. METHODS: We did a randomised controlled double-blind trial of children admitted to The Royal Children's Hospital (Melbourne, VIC, Australia) who needed intravenous maintenance hydration for 6 h or longer...
March 28, 2015: Lancet
https://read.qxmd.com/read/25304961/pediatric-status-epilepticus-management
#32
REVIEW
Nicholas S Abend, Tobias Loddenkemper
PURPOSE OF REVIEW: This review discusses the management of status epilepticus in children, including both anticonvulsant medications and overall management approaches. RECENT FINDINGS: Rapid management of status epilepticus is associated with a greater likelihood of seizure termination and better outcomes, yet data indicate that there are often management delays. This review discusses an overall management approach aiming to simultaneously identify and manage underlying precipitant causes, administer anticonvulsants in rapid succession until seizures have terminated, and identify and manage systemic complications...
December 2014: Current Opinion in Pediatrics
https://read.qxmd.com/read/25304962/consequences-of-febrile-seizures-in-childhood
#33
REVIEW
Rod C Scott
PURPOSE OF REVIEW: There is a long-standing hypothesis that febrile status epilepticus (FSE) can cause brain injury, particularly to the hippocampus. This review will evaluate recent evidence on the relationships between FSE and later epilepsy and cognitive impairments. Potential strategies for minimizing adverse outcomes will be discussed. RECENT FINDINGS: There are two major longitudinal studies evaluating the outcomes for FSE. These studies provide evidence of acute hippocampal edema that evolves to mesial temporal sclerosis in a small number of children (∼7%)...
December 2014: Current Opinion in Pediatrics
https://read.qxmd.com/read/25506733/comparative-effectiveness-of-intravenous-vs-oral-antibiotics-for-postdischarge-treatment-of-acute-osteomyelitis-in-children
#34
MULTICENTER STUDY
Ron Keren, Samir S Shah, Rajendu Srivastava, Shawn Rangel, Michael Bendel-Stenzel, Nada Harik, John Hartley, Michelle Lopez, Luis Seguias, Joel Tieder, Matthew Bryan, Wu Gong, Matt Hall, Russell Localio, Xianqun Luan, Rachel deBerardinis, Allison Parker
IMPORTANCE: Postdischarge treatment of acute osteomyelitis in children requires weeks of antibiotic therapy, which can be administered orally or intravenously via a peripherally inserted central catheter (PICC). The catheters carry a risk for serious complications, but limited evidence exists on the effectiveness of oral therapy. OBJECTIVE: To compare the effectiveness and adverse outcomes of postdischarge antibiotic therapy administered via the PICC or the oral route...
February 2015: JAMA Pediatrics
https://read.qxmd.com/read/25506783/outpatient-antibiotic-therapy-for-acute-osteomyelitis-in-children-balancing-safety-and-efficacy
#35
EDITORIAL
Pranita D Tamma, Aaron M Milstone
No abstract text is available yet for this article.
February 2015: JAMA Pediatrics
https://read.qxmd.com/read/25361906/spirometry-for-the-primary-care-pediatrician
#36
REVIEW
Robert Kaslovsky, Matthew Sadof
No abstract text is available yet for this article.
November 2014: Pediatrics in Review
https://read.qxmd.com/read/25452661/respiratory-syncytial-virus-infection-and-bronchiolitis
#37
REVIEW
Giovanni Piedimonte, Miriam K Perez
No abstract text is available yet for this article.
December 2014: Pediatrics in Review
https://read.qxmd.com/read/25422009/atopic-dermatitis-skin-directed-management
#38
REVIEW
Megha M Tollefson, Anna L Bruckner
Atopic dermatitis is a common inflammatory skin condition characterized by relapsing eczematous lesions in a typical distribution. It can be frustrating for pediatric patients, parents, and health care providers alike. The pediatrician will treat the majority of children with atopic dermatitis as many patients will not have access to a pediatric medical subspecialist, such as a pediatric dermatologist or pediatric allergist. This report provides up-to-date information regarding the disease and its impact, pathogenesis, treatment options, and potential complications...
December 2014: Pediatrics
https://read.qxmd.com/read/25334626/role-of-transthoracic-ultrasound-in-diagnosis-and-follow-up-of-cap-in-the-emergency-department
#39
Gamal Agmy, Yasser Gad, Sherif Mohamed
Ultrasound and Other Imaging PostersSESSION TYPE: Original Investigation PosterPRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PMPURPOSE: The aim of this prospective study was to define the accuracy of transthoracic ultrasound (TUS) in the diagnosis and follow up of community-acquired pneumonia (CAP) in the emergency department (ED).The role of C-reactive protein in follow up of CAP was evaluated.METHODS: This study included 284 patients with suspected CAP. During admission to ED, history, clinical examination, laboratory testing, and TUS were performed as well as chest radiograph (CXR) in two planes and CT Chest scan...
October 1, 2014: Chest
https://read.qxmd.com/read/25372854/ebola-virus-disease-in-west-africa-clinical-manifestations-and-management
#40
JOURNAL ARTICLE
Daniel S Chertow, Christian Kleine, Jeffrey K Edwards, Roberto Scaini, Ruggero Giuliani, Armand Sprecher
In resource-limited areas, isolation of the sick from the population at large has been the cornerstone of control of Ebola virus disease (EVD) since the virus was discovered in 1976. Although this strategy by itself may be effective in controlling small outbreaks in remote settings, it has offered..
November 27, 2014: New England Journal of Medicine
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